| serum TIBC | <biochemistry, haematology> A test that measures indirectly the transferrin level in the bloodstream. Transferrin is a protein that carries iron in the body. Normal values are 240 to 450 mcg/dl. This test is used to evaluate anaemia. Greater than normal total iron binding capacity can be seen in: iron deficiency anaemia, late pregnancy and polycythaemia vera. Lower than normal total iron binding capacity can be seen in cirrhosis, sickle cell anaemia, hypoproteinaemia, pernicious anaemia and haemolytic anaemia. The use of birth control pills can lead to increased total iron binding capacity measurements. Acronym: TIBC (12 Jan 1998) |
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| serum transferrin | <protein> A protein that carries iron in the bloodstream. The percentage of transferrin that has iron bound to it is increased in situations of iron overdose and in the disease haemochromatosis. Serum transferrin is decreased in cases of protein deficiency. (27 Sep 1997) |
| hyperimmune serum | Serum prepared from animals that have recently received repeated injections or applications of a chosen antigen, thus the serum should contain a very high concentration of polyclonal antibodies against that antigen. (18 Nov 1997) |
| specific serum | A monovalent antiserum, i.e., one obtained by inoculating an animal with one antigen or species or strain of bacteria. (05 Mar 2000) |
| nonimmune serum | <immunology> A serum from a subject that is not immune; a serum that is free of antibodies to a given antigen. (05 Mar 2000) |
| normal horse serum | The sterile and filtered serum of a healthy, unvaccinated horse. (05 Mar 2000) |
| normal human serum | Sterile serum obtained by pooling approximately equal amounts of the liquid portion of coagulated whole blood from eight or more persons who are free from any disease transmissible by transfusion. (05 Mar 2000) |
| normal human serum albumin | A sterile preparation of serum albumin obtained by fractionating blood plasma proteins from healthy persons; used as a transfusion material and to treat oedema due to hypoproteinaemia. Synonym: dried human albumin. (05 Mar 2000) |
| normal serum | A nonimmune serum, usually with reference to a serum obtained prior to immunization. (05 Mar 2000) |
| dried human serum | Serum prepared by drying liquid human serum by freeze-drying or by any other method that will avoid denaturation of the proteins and will yield a product readily soluble in a quantity of water equal to the volume of liquid human serum from which it was prepared. (05 Mar 2000) |
| immune serum | Blood serum containing antibodies. (14 Nov 1997) |
| immune serum globulin | A sterile solution of globulin's that contains many antibodies normally present in adult human blood; a passive immunizing agent frequently used for prophylaxis against hepatitis A. (05 Mar 2000) |
| inactivated serum | <immunology> Serum that has been heated 50캜 for 30 minutes to destroy the lytic activity of complement. (05 Mar 2000) |
| iodinated 125I serum albumin | A sterile, buffered, isotonic solution prepared to contain not less than 10 mg of radioiodinated normal human serum albumin per ml, and adjusted to provide not more than 1 mCi of radioactivity per ml; used as a diagnostic aid in determining blood volume and cardiac output. Synonym: radioiodinated serum albumin. (05 Mar 2000) |
| iodinated 131I human serum albumin | A sterile, buffered, isotonic solution prepared to contain not less than 10 mg of radioiodinated normal human serum albumin per ml, and adjusted to provide not more than 1 mCi of radioactivity per ml; used as a diagnostic aid in the measurement of blood volume and cardiac output. (05 Mar 2000) |