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ribovirus <virology> A virus that has RNA as itsgenetic material.
(09 Oct 1997)
ribozyme <molecular biology> Often referred to as RNA with catalytic capacity, an enzyme made of nucleic acid not protein that catalyse chemical reactions, often the breakdown of other RNAs.
Of particular interest because of the implications for self replicating systems in the earliest stages of the evolution of (terrestrial) life.
Their discovery in the mid-1980s refuted the concept that only proteins could be biological catalysts. There is potential for their use as pharmaceuticals and industrial catalysts.
(13 Nov 1997)
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  • Ribosomal Protein S6 - »õâ A ribosomal protein that may play a role in controlling cell growth and proliferation. It is a major substrate of RIBOSOMAL PROTEIN S6 KINASES and plays a role in regulating the translation (TRANSLATION, GENETIC) of RNAs that contain an RNA 5' TERMINAL OLIGOPYRIMIDINE SEQUENCE.
    Synonyms : Protein S6, Ribosomal
  • Ribosomal Protein S6 Kinases - »õâ A family of protein serine/threonine kinases which act as intracellular signalling intermediates. Ribosomal protein S6 kinases are activated through phosphorylation in response to a variety of HORMONES and INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS. Phosphorylation of RIBOSOMAL PROTEIN S6 by enzymes in this class results in increased expression of 5' TOP MRNAS. Although specific for RIBOSOMAL PROTEIN S6 members of this class of kinases can act on a number of substrates within the cell. The immunosuppressant SIROLIMUS inhibits the activation of ribosomal protein S6 kinases.
    Synonyms : Ribosomal Protein S6 Kinase, S6-H4 Kinase, S6 H4 Kinase
  • Ribosomal Protein S6 Kinases, 70-kDa - »õâ A family of ribosomal protein S6 kinases that are considered the major physiological kinases for RIBOSOMAL PROTEIN S6. Unlike RIBOSOMAL PROTEIN S6 KINASES, 90KDa the proteins in this family are sensitive to the inhibitory effects of RAPAMYCIN and contain a single kinase domain. They are referred to as 70kDa proteins, however ALTERNATIVE SPLICING of mRNAs for proteins in this class also results in 85kDa variants being formed.
    Synonyms : Ribosomal Protein S6 Kinases, 70 kDa, S6 Kinase, p70
  • Ribosomal Protein S6 Kinases, 90-kDa - »õâ A family of ribosomal protein S6 kinases that are structurally distinguished from RIBOSOMAL PROTEIN S6 KINASES, 70-KDA by their apparent molecular size and the fact they contain two functional kinase domains. Although considered RIBOSOMAL PROTEIN S6 KINASES, members of this family are activated via the MAP KINASE SIGNALING SYSTEM and have been shown to act on a diverse array of substrates that are involved in cellular regulation such as RIBOSOMAL PROTEIN S6 and CAMP RESPONSE ELEMENT-BINDING PROTEIN.
    Synonyms : MAPKAP Kinase-1, MAPKAP-K1, MAPKAPK1, Ribosomal Protein S6 Kinase, 90-kDa, p90 Ribosomal S6 Kinase, p90(rsk), pp90(rsk), MAP Kinase Activated Kinase 1, MAP Kinase Activated Protein Kinase 1, MAPKAP Kinase 1, Ribosomal Protein S6 Kinase, 90 kDa
  • Ribosomal Proteins - »õâ Proteins found in ribosomes. They are believed to have a catalytic function in reconstituting biologically active ribosomal subunits.
    Synonyms : Ribosomal Protein, Protein, Ribosomal
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ribosome Cellular organelle that is the site of protein synthesis.
Ãâó: science.education.nih.gov/supplements/nih1/genetic...
ribonucleotide one of the building blocks that make up genetic material (DNA and RNA). Nucleotides consist of a base (adenine, cytosine, guanine, thymine, or uracil), a sugar, and a phosphate group.
Ãâó: www.aegis.com/pubs/beta/1999/BE991221.html
ribosome A very small non-membranous cell organelle composed of protein and RNA that is the site of protein synthesis, and is found in the nucleus, cytoplasm, mitochondria and plastids of a cell.
Ãâó: www.botanyvt.com/pages/dictionary.shtml
ribonucleic acid A molecule that carries the genetic message from DNA to a cellular protein-producing mechanisms.
Ãâó: www.nsc.org/ehc/glossar2.htm
ribonucleoprotein a nucleoprotein that contains RNA, or ribonucleic acid; a nucleoprotein is the combination of a protein molecule and a nucleic acid compound; nucleic acids are complex chemical compounds found in all living cells and viruses and are important in the transfer of hereditary information as well as controlling cellular functions
Ãâó: www.kentuckyawake.org/templates/glossary/
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