| tolbutamide 4-hydroxylase | <enzyme> Several isoenzymes of cytochrome p-450 catalyze this reaction, including cyp2c8, cyp2c9 and cyp2c10 Registry number: EC 1.14.99.- Synonym: phenytoin hydroxylase (26 Jun 1999) |
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| ent-kaurenoic acid 13-hydroxylase | <enzyme> Forms steviol (ent-kaur-16-en-13-ol-19-oic acid) using NADPH and o2; n-terminal amino acid sequence given in first source Registry number: EC 1.14.13.- Synonym: ent-ka 13-hydroxylase (26 Jun 1999) |
| erythromycin C-12 hydroxylase | <enzyme> Required for the c-12 hydroxylation of the macrolactone ring in erythromycin synthesis; mw 44 kD; from saccharopolyspora erythraea; amino acid sequence given in first source Registry number: EC 1.14.- Synonym: hydroxylase eryk, eryk gene product, cytochrome p-450(eryk) (26 Jun 1999) |
| tryptophan hydroxylase | <enzyme> An enzyme that catalyses the hydroxylation of tryptophan to 5-hydroxytryptophan in the presence of NADPH and molecular oxygen. It is important in the biosynthesis of serotonin. Chemical name: L-tryptophan,tetrahydropteridine:oxygen oxidoreductase (5-hydroxylating) Registry number: EC 1.14.16.4 (12 Dec 1998) |
| estradiol 15 alpha-hydroxylase | <enzyme> Catalyses the conversion of estradiol to 15alpha-hydroxyestradiol Registry number: EC 1.14.99.- Synonym: e15a-hydroxylase (26 Jun 1999) |
| estradiol 16 alpha-hydroxylase | <enzyme> Cyp2c11 is a male-specific cyp isoform Registry number: EC 1.14.99.- Synonym: 16 alpha-hydroxylase, estrone 16 alpha-hydroxylase, 16alpha-hydroxylase, steroid 16 alpha-hydroxylase, estrone 3-sulfate 16 alpha-hydroxylase, cytochrome p450cmf, cytochrome p450 2c, cytochrome p450iic11, cytochrome p450(ut-a), cytochrome p4502c-rml5, cytochrome p450h, cytochrome p450(male), cytochrome p4502c, cytochrome p450 2c3, cytochrome p450 2c9, oestrogen 16-hydroxylase, cyp2c3 gene product, cyp2c11 gene product, cytochrome p450 2c11, cyp 2d-9, cytochrome p450(tb), cyp2c9, cytochrome p-450(m1), cyp2c11 (26 Jun 1999) |
| estrogen 2-hydroxylase | <enzyme> Same enzyme for hydroxylation in 2 or 4 position Registry number: EC 1.14.99.- Synonym: estrogen 4-hydroxylase, ethinylestradiol 2-hydroxylase (26 Jun 1999) |
| juglone hydroxylase | <enzyme> Catalyses the hydroxylation of juglone to 3-hydroxyjuglone; requires o2, but does not incorporate it into juglone; does not require nad or flavin cofactors Registry number: EC 1.10.3.- Synonym: naphthazarin hydroxylase, 1,4-naphthoquinone hydroxylase (26 Jun 1999) |
| tyramine beta-hydroxylase | <enzyme> This enzyme is dopamine beta-hydroxylase in mammals, but is a different enzyme in lobsters Registry number: EC 1.14.- (26 Jun 1999) |
| tyrosine hydroxylase | <enzyme> Enzyme required for the synthesis of the neurotransmitters noradrenaline and dopamine. (18 Nov 1997) |
| ferulic acid hydroxylase | <enzyme> Fah1 from arabidopsis thaliana Registry number: EC 1.14.- Synonym: fah1 gene product (26 Jun 1999) |
| kynurenine 3-hydroxylase | <enzyme> Formerly EC 1.14.1.2 Registry number: EC 1.14.13.9 Synonym: kynurenine hydroxylase, kynurenine 3-hydroxylase (26 Jun 1999) |
| flavonoid 3',5'-hydroxylase | <enzyme> Catalyses the 3',5' hydroxylation of naringenin and eriodictyol to form 5,7-3',4',5'-pentahydroxyflavone and 3',5' hydroxylation of dihydrokaempferol and dihydroquercetin to form dihydromyricetin; controls flower colour Registry number: EC 1.14.13.- (26 Jun 1999) |
| 16-hydroxypalmitic acid hydroxylase | <enzyme> P-450 dependent hydroxylation of 16-hydroxypalmitic acid at the c9 or c10 position in the presence of NADPH and oxygen Registry number: EC 1.14.13.- (26 Jun 1999) |
| 17-hydroxylase deficiency syndrome | <syndrome> Congenital deficiency of adrenocortical, and possibly ovarian, steroid C-17a hydroxylase; the resulting excessive secretion of corticosterone and deoxycorticosterone produces hypertension and hypokalaemic alkalosis; absence of aldosterone secretion in such patients may indicate a multiple enzymic deficiency. (05 Mar 2000) |