| leukaemia, calla-positive | Acute leukaemia in which lymphocytes are positive for the common acute lymphoblastic leukaemia antigen (calla). (12 Dec 1998) |
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| leukaemia cutis | Yellow-brown, red, blue-red, or purple, sometimes nodular lesions associated with diffuse infiltration of leukaemic cells in the skin; the involvement may be diffuse and generalised, i.e., so-called universal leukaemia cutis, or it may be localised. (05 Mar 2000) |
| leukaemia, erythroblastic, acute | A myeloproliferative disorder characterised by neoplastic proliferation of erythroblastic and myeloblastic elements with atypical erythroblasts and myeloblasts in the peripheral blood. (12 Dec 1998) |
| leukaemia, experimental | Leukaemia induced experimentally by administration of various leukemogenic agents, viruses, radiation or transplantation. (12 Dec 1998) |
| leukaemia, feline | A neoplastic disease of cats frequently associated with feline leukaemia virus infection. (12 Dec 1998) |
| leukaemia, hairy cell | A neoplastic disease of the lymphoreticular cells which is considered to be a rare type of chronic leukaemia; it is characterised by an insidious onset, splenomegaly, anaemia, granulocytopenia, thrombocytopenia, little or no lymphadenopathy, and the presence of "hairy" or "flagellated" cells in the blood and bone marrow. (12 Dec 1998) |
| Leukaemia inhibitory factor | <growth factor> Polypeptide growth factor or cytokine with wide range of activities. Regulates growth and differentiation of primordial germ cells and embryonic stem cells but has effects on peripheral neurons, osteoblasts, adipocytes and various cells of the myeloid lineage. Given to adult animals induces weight loss, behavioural disorders and bone abnormalities. Many of the effects of LIF in vitro can be mimicked by IL-6, oncostatin M and ciliary neurotrophic factor, all of which interact indirectly with gp130, a shared tranducer subunit. (18 Nov 1997) |
| leukaemia l5178 | An experimental lymphocytic leukaemia of mice. (12 Dec 1998) |
| leukaemia, lymphocytic | Leukaemia associated with hyperplasia and overactivity of the lymphoid tissue. There are increased numbers of circulating malignant lymphocytes and lymphoblasts. (12 Dec 1998) |
| leukaemia, masT-cell | A disorder characterised by the presence of large numbers of tissue mast cells in the peripheral blood. (12 Dec 1998) |
| leukaemia, megakaryocytic, acute | Nonlymphocytic leukaemia in which 20-30% of the bone marrow or peripheral blood cells are of megakaryocyte lineage. Myelofibrosis or increased bone marrow reticulin is common. (12 Dec 1998) |
| leukaemia, myelocytic, acute | Progressive, malignant disease of the myeloid tissue in which the granular, polymorphonuclear leukocytes and their precursors predominate. (12 Dec 1998) |
| leukaemia, myeloid | Form of leukaemia characterised by an uncontrolled proliferation of the myeloid lineage and their precursors in the bone marrow and other sites. (12 Dec 1998) |
| leukaemia, nonlymphocytic, acute | Acute leukaemia distinguished from acute lymphocytic leukaemia (all) by the morphology of the marrow and blood leukaemic cells. Cytoplasmic granules are usually present and the nucleus is usually large and irregular. Anll is more common in adults than all and occurs at any age. (12 Dec 1998) |
| leukaemia of fowls | A group of transmissible, virus-induced diseases of chickens, characterised by proliferation of immature erythroid, myeloid, or lymphoid cells. It includes both leukaemic and solid-tumour forms. (12 Dec 1998) |
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