| BPP | biophysical profile; bovine pancreatic polypeptide; bradykinin potentiating peptide |
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| CGRP | calcitonin gene-related peptide |
| cGRP | calcitonin gene-related peptide |
| CGRPR | calcitonin gene related peptide receptor |
| CLIP | capitolunate instability pattern; corticotropin-like intermediate lobe peptide |
| eosinophil chemotactic peptide | <protein> Tetrapeptides (of which two are identified: VGSE and AGSE) released by mast cells and that are said to both attract and activate eosinophils. (18 Nov 1997) |
|---|---|
| UDP-N-acetylglucosamine-peptide beta-N-acetylglucosaminyltransferase | <enzyme> Responsible for the addition of o-linked n-acetylglucosamine to proteins Registry number: EC 2.4.1.- Synonym: udp-glcnac-peptide-glcnac-transferase, glcnac transferase (26 Jun 1999) |
| formyl peptide | <biochemistry> Informal term for small peptides with a formylated N terminal methionine and usually a hydrophobic amino acid at the carboxy terminal end (fMetLeuPhe is the most commonly used). These peptides stimulate the motor and secretory activities of leucocytes, particularly neutrophils and monocytes, that have a specific receptor (about 60 kD) of high affinity (Kd approximately 10exp 8M). Leucocytes show chemotaxis towards formyl peptides but the term chemotactic peptides understates the range of activities the molecules will trigger. Thought to be synthetic analogues of bacterial signal sequences though this is unproven. The leucocytes of many animals (e.g. Pig, cow, chicken) do not respond. (18 Nov 1997) |
| leader peptide | <molecular biology> In the regulation of gene expression for enzymes concerned with amino acid synthesis in prokaryotes, the leader sequence codes for the leader peptide that contains several residues of the amino acid being regulated. Transcription is closely linked to translation and if translation is retarded by limited supply of amino acyl tRNA for the specific amino acid, the mode of transcription of the leader sequence permits full transcription of the operon genes, otherwise complete transcription of the leader sequence prematurely terminates transcription of the operon. (18 Nov 1997) |
| lysergyl peptide synthetase | <enzyme> Multifunctional enzyme which forms non-cyclol d-lysergyl peptide lactams; consists of two polypeptide chains - lps 1 binds the 3 amino acids (ala, phe and pro) of the peptide nucleus and lps 2 binds d-lysergic acid Registry number: EC 6.3.2.- Synonym: d-lysergylpeptide synthetase (26 Jun 1999) |
| acetyl phosphate | CH3CO-OPO32-;a "high energy" phosphate that acts as an acetate donor in the metabolism of various bacteria. Synonym: acetic phosphoric anhydride. (05 Mar 2000) |
| acidulated phosphate fluoride | <chemical> Phosphoric acid, mixt. With sodium fluoride (naf). A sodium fluoride solution, paste or powder, which has been acidulated to pH 3 to 4 and buffered with a phosphate. It is used in the prevention of dental caries. Pharmacological action: fluorides, topical. Chemical name: Phosphoric acid, mixt. With sodium fluoride (NaF) (12 Dec 1998) |
| acyl dihydroxyacetone phosphate oxidoreductase | <enzyme> Forms acyl-sn-glycerol 3-phosphate; uses NADPH Registry number: EC 1.1.1.- (26 Jun 1999) |
| adenosine 3',5'-cyclic phosphate phosphodiesterase | <enzyme> An enzyme that catalyses the hydrolysis of adenosine 3',5'-cyclic phosphate forming 5'-AMP. A crucial step in the regulation of cellular adenosine 3',5'-cyclic phosphate levels. Inhibited by caffeine. Synonym: cAMP phosphodiesterase. (05 Mar 2000) |
| adenosine 3'-phosphate | 3'-Adenylic acid. See: adenylic acid. (05 Mar 2000) |
| adenosine 3'-phosphate 5'-phosphosulfate | 3'-phosphoadenosine 5'-phosphosulfate;an intermediate in the formation of urinary ethereal sulfates, notable for containing a "high energy" sulfate bond; the 3'-OH of adenosine is replaced by -OPO3H2, the 5'-OH by -OP(O2H)-OSO3H. Synonym: active sulfate. Acronym: PAPS (05 Mar 2000) |
| adenosine 5'-phosphate | 5'-Adenylic acid. See: adenylic acid. (05 Mar 2000) |
| adenosine cyclic phosphate | An activator of phosphorylase kinase and an effector of other enzymes, formed in muscle from ATP by adenylate cyclase and broken down to 5'-AMP by a phosphodiesterase; sometimes referred to as the "second messenger." A related compound (2',3') is also known. Synonym: cyclic adenylic acid, cyclic AMP, cyclic phosphate. Acronym: cAMP (05 Mar 2000) |
| alkyldihydroxyacetone phosphate acyltransferase | <enzyme> Catalyses acylation of alkyl-dhap Registry number: EC 2.3.1.- Synonym: adapat (26 Jun 1999) |
| alkyl dihydroxyacetone phosphate oxidoreductase | <enzyme> Forms alkyl-sn-glycerol 3-phosphate, uses NADPH Registry number: EC 1.1.1.- (26 Jun 1999) |
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