| BOR | basal optic root; before time of operation; bowels open regularly; branchio-oto-renal [syndrome] |
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| COT | colony overlay test; content of thought; contralateral optic tectum; critical off-time |
| DIDMOA | diabetes insipidus-diabetes mellitus-optic atrophy [syndrome] |
| DIMOAD | diabetes insipidus, diabetes mellitus, optic atrophy, deafness |
| DJOA | dominant juvenile optic atrophy |
| optic neuropathy, ischemic | A severely blinding disease resulting from loss of the arterial blood supply to the optic nerve as a result of occlusive disorders of the nutrient arteries. Optic neuropathy is divided into anterior, which causes a pale oedema of the optic disk, and posterior, in which the optic disk is not swollen and the abnormality occurs between the globe and the optic chiasm. Ischemic anterior optic neuropathy usually causes a loss of vision that may be sudden or occur over several days; ischemic posterior optic neuropathy is uncommon and the diagnosis depends largely upon exclusion of other causes, chiefly stroke and brain tumour. (12 Dec 1998) |
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| optic papilla | The portion of the optic nerve seen in the fundus with the ophthalmoscope. It is formed by the meeting of all the retinal ganglion cell axons as they enter the optic nerve. Because the retina at the optic disk has no photoreceptors there is a corresponding blind spot in the visual field. (12 Dec 1998) |
| optic part of retina | The internal layer of the retina containing the neural elements, as distinguished from the outer leaf of the retina, or pigmented layer. Synonym: pars optica retinae, neural layer of retina, optic part of retina, stratum cerebrale retinae. (05 Mar 2000) |
| optic pit | A congenital structural defect of the optic nerve head. (05 Mar 2000) |
| optic placodes | Paired ectodermal placode's that become invaginated to form the embryonic lens vesicles. Synonym: optic placodes. (05 Mar 2000) |
| optic radiation | The massive, fanlike fibre system passing from the lateral geniculate body of the thalamus to the visual cortex (striate or calcarine cortex, area 17 of Brodmann); the fibres follow the retrolenticular and sublenticular limbs of the internal capsule into the corona radiata but they curve back along the lateral wall of the temporal and occipital horns of the lateral ventricle to the striate cortex on the medial surface and pole of the occipital lobe. Synonym: radiatio optica, geniculocalcarine radiation, geniculocalcarine tract, Gratiolet's fibres, Gratiolet's radiation, occipitothalamic radiation, Wernicke's radiation. (05 Mar 2000) |
| optic recess | A diverticulum extending forward from the anterior part of the third ventricle above the optic chiasm. Synonym: recessus opticus. (05 Mar 2000) |
| optic sign | <microscopy> For uniaxial materials, by definition, the sign is positive if the value epsilon minus omega is positive, and negative if epsilon - omega is negative. For biaxial materials, the sign is positive if gamma is the acute bisectrix, and negative if alpha is the acute bisectrix, or positive if gamma - beta greater than beta - alpha and negative if gamma - beta less than beta - alpha (05 Aug 1998) |
| optic stalk | The constricted proximal portion of the optic vesicle in the embryo; it develops into the optic nerve. Pineal stalk, the attachment of the pineal body to the roof of the third ventricle; it contains the pineal recess of the third ventricle. Pituitary stalk, a process comprising the tuberal part investing the infundibular stem that attaches the hypophysis to the tuber cinereum at the base of the brain. Yolk stalk, the narrowed connection between the intraembryonic gut and the yolk sac; its walls are splanchnopleure. Synonym: umbilical duct, vitelline duct, vitellointestinal duct. (05 Mar 2000) |
| optic tectum | <anatomy> A region of the midbrain in which input from the optic nerve is processed. Because the retinally derived neurons of the optic nerve map onto the optic tectum in a defined way, the question of how this specificity is determined has been a long standing problem in cell biology. Although there is some evidence for adhesion gradients and for some adhesion specificity, the problem is unresolved. (11 Jan 1998) |
| optic tract | The continuation of the optic nerve fibres beyond (behind) the latter's hemidecussation in the optic chiasm; each of the two symmetrical optic tracts is composed of fibres originating from the temporal half of the retina of the ipsilateral eye and a nearly equal number of fibres from the nasal half of the contralateral retina; it forms a compact, somewhat flattened fibre band passing caudolaterally alongside the base of the hypothalamus and over the basal surface of the crus cerebri; most of its fibres terminate in the lateral geniculate body; a smaller number of fibres enter the brachium of the superior colliculus, to terminate in the superior colliculus and the pretectal region. Synonym: tractus opticus. (05 Mar 2000) |
| optic vesicle | In the embryo, one of the paired evaginations from the ventrolateral walls of the forebrain from which the sensory and pigment layers of the retina develop. Synonym: vesicula ophthalmica, ocular vesicle, optic vesicle. (05 Mar 2000) |
| excavation of optic disc | The normally occurring depression or pit in the centre of the optic disc. Synonym: excavatio disci, depression of optic disk, excavatio papillae, physiologic cup, physiologic excavation. (05 Mar 2000) |
| lateral root of optic tract | The larger division of the posterior end of the optic tract that terminates in the lateral geniculate body. Synonym: radix lateralis tractus optici. (05 Mar 2000) |
| Leber's hereditary optic atrophy | Hereditary degeneration of the optic nerve and papillomacular bundle with resulting rapid loss of central vision, progressive for several weeks, then usually stationary with permanent central scotoma; age of onset is variable, most often in the third decade; more males than females are affected and transmission is cytoplasmic and strictly on the female side. Mutation on the mitochondrial chromosome involved, which presumably interacts with an X-linked mutant. This mechanism may explain the bizarre sex ratio, which differs significantly from one country to another. (05 Mar 2000) |