| 영문 | Alzheimer's disease | 한글 | 알츠하이머병 |
|---|---|---|---|
| 설명 | 퇴행성 뇌병. 노인에서의 치매의 원인 중 가장 흔한 형태이다. 병리조직학적으로는 뇌의 전반적인 위축, 뇌실의 확장, 신경섬유의 다발성 병터(신경섬유뒤틀림)와 노인반(neuritic plaque) 등이 특징이다. 임상적인 특징은 점진적인 기억-판단-언어능력 등 지적인 기능의 감퇴와 일상생활능력-인격-행동양상의 장애이다. 병에 걸리면 초기에는 이름-날짜-장소와 같은 것들이 기억에서 사라지고, 심해지면 화장실을 가거나 요리를 하거나 신을 신는 일 등의 일상생활조차도 잊게 된다. 동시에 우울증세나 인격의 황폐, 격한 행동 등의 정신의학적인 증세도 동반된다. 이러한 증세들이 점전적으로 진행되어 결국은 죽음에 이르게 된다. 발병 후 서서히 죽음에 이르는 기간은 6~8년 정도이지만 사람에 따라 20년이 넘는 경우도 있다. |
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| 영문 | Addison disease | 한글 | 애디슨병 |
|---|---|---|---|
| 설명 | 부신겉질의 병터로 인하여 부신겉질의 호르몬이 나오지 못해서 생기는 병. 우리나라에서 가장 많은 원인은 결핵이다. 애디슨병에서는 부신겉질의 파괴에 의해서 부신겉질에서 나오는 호르몬이 없어지므로 콩팥에서 물의 흡수장애로 인해 탈수상태가 지속되며, 스트레스 호르몬의 결핍에 의해서 만성피로, 체중감소 등의 증상이 생기며, 뇌하수체에서 부신겉질의 분비를 높이는 부신겉질자극호르몬의 과다 분비로 인해서 같이 분비되는 멜라닌자극호르몬에 의해 얼굴과 입술에 과도한 색소의 침착을 볼 수 있다. |
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| 영문 | inflammatory bowel disease | 한글 | 염증성창자병 |
|---|---|---|---|
| 설명 | 위장관을 침범하는 정확한 원인이 밝혀지지 않은 만성적인 염증성 질환을 말한다. 크게 ‘궤양성 대장염’(ulcerative colitis)과 ‘크론병’(Crohn's disease)의 두 종류로 구분된다. 백인, 유태인에 많고 흑인이나 동양인에는 드물지만 동양인에서 점차 증가추세에 있다. 호발연령은 15~35세 사이이다. 증상은 ‘궤양성 대장염’의 경우, 설사(혈변 및 점액변), 뒤무직, 복통, 복부압통, 체중감소 등이 주로 나타나며 ‘크론병’에서는 설사와 체중감소, 우하복부 종류, 항문주위 이상, 복부압통 등이 나타난다. 진단은 병력과 방사선학적 검사, 직장경 및 대장 내시경검사, 직장 및 대장의 조직검사로 하며 치료는 내과적인 치료가 원칙이나 내과적 치료에 듣지 않거나 합병증이 생길 경우에는 외과적 치료를 시행한다. ‘궤양성 대장염’의 경우에는 ‘대장암’을 예방하기 위해서 외과적 치료를 하기도 한다. ‘궤양성 대장염’과 ‘크론 병’외에 염증성 창자병에 속하는 ‘베체트 병’은 재발성 구강내 궤양, 피부 병변, 안구부 염증, 외음부 궤양, 관절염 증상, 위창자관 증상(복통, 장출혈), 부고환염 등의 증상을 나타내는데 진단과 치료는 ‘궤양성 대장염’, ‘크론 병’과 비슷하다. |
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| 영문 | Wilson's disease | 한글 | 윌슨병 |
|---|---|---|---|
| 설명 | 간이나 뇌에 구리가 비정상적으로 쌓여 일어나는 유전성 대사병. 간경화증이나 신경 증상이 따르는데, 손 떨림이나 언어 장애가 생기고 눈의 각막 주위에 녹갈색 고리가 나타난다. 영국의 신경과 의사 윌슨(Wilson)이 분류한 병이다. 보통염색체 열성으로 유전된다. 한국에서도 현재까지 50여 예가 보고되어 있다. 이병은 보통염색체 열성으로 유전되며, ATP7B라는 윌슨병 유전자가 13번 염색체에 위치한다. 특징으로 구리가 간, 뇌 및 각막에 축적하여 만성 간염 또는 간경화와 같은 간손상을 일으키고, 뇌 특히 렌즈핵의 퇴행 변화와 각막모서리에 녹갈색의 Kayser-Fleischer 고리를 형성한다. 임상증상의 발현은 보통 5~15세에 시작하는데 30~40세가 되도록 증상이 없을 수도 있다. |
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| 영문 | hyaline membrane disease | 한글 | 유리질막병 |
|---|---|---|---|
| 설명 | 허파 성숙도의 미숙으로 허파꽈리를 팽창시키는 물질(표면활성제)이 부족하여 호흡곤란이 초래되는 병으로서 미숙아에 호발하는데, 출생시 임신기간보다도 허파 성숙 정도가 더 관여된다. 단일 병으로서는 사망률이 가장 높으며(약 30%), 신생아의 대표적인 병이다. 임상적으로는 미숙아, 생후 6~8시간내 호흡곤란증세 출현과 생후 24~48시간의 증상 악화, 생후 2~3일간 인공적으로 산소를 공급하지 않으면 호흡을 계속시킬 수가 없으며 점점더 산소의 공급 의존도가 높아지며, 동맥혈액속의 산소농도가 내려가고 이산화탄소의 농도가 높으며, 흉부 방사선 소견을 참작하여 진단한다. 환아는 숙련된 간호 인력과 첨단 의료 장비가 설치된 신생아 집중 치료실에서 치료하여야 한다. 예후는 증세의 경중에 따라 다르고 사망률은 30~50% 된다. 어떤 아기에 있어서는 치료 후에 눈이나 기관지허파 계통에 장애를 일으키는 산소중독증이 보고되고 있다. |
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| OHD | hydroxyvitamin D; Office of Human Development; Ondine-Hirschsprung disease; organic heart disease |
|---|---|
| RHD | radiological health data; relative hepatic dullness; renal hypertensive disease; rheumatic heart dis... |
| VHD | valvular heart disease; viral hematodepressive disease |
| NYHA | New York Heart Association Heart Disease에 대한 Functional Classification &nbs... |
| AHA | acetohydroxamic acid; acquired hemolytic anemia; acute hemolytic anemia; American Heart Association;... |
| hairy heart | Acute pericarditis with fibrinous exudate. See: bread-and-butter pericardium. Synonym: hairy heart, pericarditis villosa, shaggy pericardium. (05 Mar 2000) |
|---|---|
| premature contraction of the heart | When a single heartbeat occurs earlier than normal. This phenomenon can be within normal limits or represent a medically significant arrhythmia. (12 Dec 1998) |
| sabot heart | <radiology> The radiographic configuration of the heart in the tetralogy of Fallot; the elevated apex gives a silhouette like that of a wooden shoe Synonym: sabot heart, wooden-shoe heart. (05 Mar 2000) |
| heart | To give heart to; to hearten; to encourage; to inspirit. "My cause is hearted; thine hath no less reason." (Shak) To form a compact center or heart; as, a hearting cabbage. 1. <anatomy> A hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. "Why does my blood thus muster to my heart!" (Shak) In adult mammals and birds, the heart is four-chambered, the right auricle and ventricle being completely separated from the left auricle and ventricle; and the blood flows from the systematic veins to the right auricle, thence to the right ventricle, from which it is forced to the lungs, then returned to the left auricle, thence passes to the left ventricle, from which it is driven into the systematic arteries. In fishes there are but one auricle and one ventricle, the blood being pumped from the ventricle through the gills to the system, and thence returned to the auricle. In most amphibians and reptiles, the separation of the auricles is partial or complete, and in reptiles the ventricles also are separated more or less completely. The so-called lymph hearts, found in many amphibians, reptiles, and birds, are contractile sacs, which pump the lymph into the veins. 2. The seat of the affections or sensibilities, collectively or separately, as love, hate, joy, grief, courage, and the like; rarely, the seat of the understanding or will; usually in a good sense, when no epithet is expressed; the better or lovelier part of our nature; the spring of all our actions and purposes; the seat of moral life and character; the moral affections and character itself; the individual disposition and character; as, a good, tender, loving, bad, hard, or selfish heart. "Hearts are dust, hearts' loves remain." (Emerson) 3. The nearest the middle or center; the part most hidden and within; the inmost or most essential part of any body or system; the source of life and motion in any organization; the chief or vital portion; the center of activity, or of energetic or efficient action; as, the heart of a country, of a tree, etc. "Exploits done in the heart of France." (Shak) "Peace subsisting at the heart Of endless agitation." (Wordsworth) 4. Courage; courageous purpose; spirit. "Eve, recovering heart, replied." (Milton) "The expelled nations take heart, and when they fly from one country invade another." (Sir W. Temple) 5. Vigorous and efficient activity; power of fertile production; condition of the soil, whether good or bad. "That the spent earth may gather heart again." (Dryden) 6. That which resembles a heart in shape; especially, a roundish or oval figure or object having an obtuse point at one end, and at the other a corresponding indentation, used as a symbol or representative of the heart. 7. One of a series of playing cards, distinguished by the figure or figures of a heart; as, hearts are trumps. 8. Vital part; secret meaning; real intention. "And then show you the heart of my message." (Shak) 9. A term of affectionate or kindly and familiar address. "I speak to thee, my heart." Heart is used in many compounds, the most of which need no special explanation; as, heart-appalling, heart-breaking, heart-cheering, heart-chilled, heart-expanding, heart-free, heart-hardened, heart-heavy, heart-purifying, heart-searching, heart-sickening, heart-sinking, heart-stirring, heart-touching, heart-wearing, heart-whole, heart-wounding, heart-wringing, etc. After one's own heart, conforming with one's inmost approval and desire; as, a friend after my own heart. "The Lord hath sought him a man after his own heart." (1 Sam. Xiii. 14) at heart, in the inmost character or disposition; at bottom; really; as, he is at heart a good man. By heart, in the closest or most thorough manner; as, to know or learn by heart. "Composing songs, for fools to get by heart" (that is, to commit to memory, or to learn thoroughly). For my heart, for my life; if my life were at stake. "I could not get him for my heart to do it." . Heart bond, any heartshaped, spatangoid sea urchin. See Spatangoid. Heart wheel, a form of cam, shaped like a heart. See Cam. In good heart, in good courage; in good hope. Out of heart, discouraged. Poor heart, an exclamation of pity. To break the heart of. To bring to despair or hopeless grief; to cause to be utterly cast down by sorrow. To bring almost to completion; to finish very nearly; said of anything undertaken; as, he has broken the heart of the task. To find in the heart, to be willing or disposed. "I could find in my heart to ask your pardon." . To have at heart, to desire (anything) earnestly. To have in the heart, to purpose; to design or intend to do. To have the heart in the mouth, to be much frightened. To lose heart, to become discouraged. To lose one's heart, to fall in love. To set the heart at rest, to put one's self at ease. To set the heart upon, to fix the desires on; to long for earnestly; to be very fond of. To take heart of grace, to take courage. To take to heart, to grieve over. To wear one's heart upon one's sleeve, to expose one's feelings or intentions; to be frank or impulsive. With all one's whole heart, very earnestly; fully; completely; devotedly. Origin: OE. Harte, herte, heorte, AS. Heorte; akin to OS. Herta, OFies. Hirte, D. Hart, OHG. Herza, G. Herz, Icel. Hjarta, Sw. Hjerta, Goth. Hairt, Lith. Szirdis, Russ. Serdtse, Ir. Cridhe, L. Cor, Gr, . Cf. Accord, Discord, Cordial, 4th Core, Courage. Source: Websters Dictionary (01 Mar 1998) |
| heart and lung transplant | A surgical procedure which replaces a diseased heart and lungs with a healthy heart and lungs from a donor. They have been used in patients with primary pulmonary hypertension and isolated severe heart and lung disease. They are not recommended for those with associated systemic disorders such as diabetes or autoimmune illness. Those with liver and/or kidney disease are also not candidates. Long-term outcomes are still being studied. (27 Sep 1997) |
| heart aneurysm | An aneurysmal dilatation of a portion of the wall of the ventricle, usually the left, or, rarely, a saccular protrusion through it (false aneurysm of the heart). It is usually consequent to myocardial infarction but other causes such as bacterial endocarditis or trauma have been described. (12 Dec 1998) |
| heart antigen | A diphosphatidyl glycerol that is found in the membrane of Treponema pallidum and is the antigen detected by the Wasserman test for syphilis. (18 Nov 1997) |
| heart arrest | Sudden and usually momentary cessation of cardiac function. This sudden cessation may, but not usually, lead to death, sudden, cardiac. (12 Dec 1998) |
| heart arrest, induced | Arrest of the contraction of the myocardium by the use of cardioplegic chemical compounds (cardioplegic solutions) or of cold during heart surgery. (12 Dec 1998) |
| heart, artificial | A pumping mechanism that duplicates the output, rate, and blood pressure of the natural heart. It may replace the function of the entire heart or a portion of it, and may be an intracorporeal, extracorporeal, or paracorporeal heart. (12 Dec 1998) |
| heart-assist devices | Small pumps, often implantable, designed for temporarily assisting the heart, usually the left ventricle, to pump blood; they consist of a pumping chamber and a power source, which may be partially or totally external to the body and activated by electromagnetic motors; the devices are used after myocardial infarction or to wean the repaired heart from the heart-lung machine after open-heart surgery. (12 Dec 1998) |
| heart atrium | The upper right and left chambers of the heart. (12 Dec 1998) |
| heart attack | This refers to that damage that occurs to the heart when one of the coronary arteries becomes occluded. Common symptoms include crushing, substernal chest pain that may radiate to the jaw or the left arm, accompanied by nausea, sweating and shortness of breath. Fainting is a more uncommon presentation. (27 Sep 1997) |
| heart auscultation | Act of listening for sounds within the heart. (12 Dec 1998) |
| heart beat | A complete cardiac cycle, including spread of the electrical impulse and the consequent mechanical contraction. Synonym: ictus cordis. (05 Mar 2000) |