| toxic epidermal necrolysis | A syndrome in which a large portion of the skin becomes intensely erythematous with epidermal necrosis, and peels off in the manner of a second-degree burn, often simultaneous with the formation of flaccid bullae, resulting from drug sensitivity or of unknown cause; the level of separation is subepidermal, unlike staphylococcal scalded skin syndrome in which there is subcorneal change. Synonym: Lyell's syndrome. (05 Mar 2000) |
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| toxic equivalent | The amount of toxin or other poison per kilogram of body weight necessary to kill an animal. (05 Mar 2000) |
| toxic haemoglobinuria | Haemoglobinuria occurring after the ingestion of various poisons, in certain blood diseases, and in certain infections. (05 Mar 2000) |
| toxic hydrocephalus | Thrombotic hydrocephalus associated with some general infection or toxic state. (05 Mar 2000) |
| toxic megacolon | <gastroenterology, surgery> An acute nonobstructive dilation of the colon, seen in advanced ulcerative colitis and Crohn's disease. (12 Jan 1998) |
| toxic nephrosis | Acute oliguric renal failure due to chemical poisons, septicaemia, or bacterial toxaemia; frequently associated with extensive necrosis of proximal convoluted tubules. (05 Mar 2000) |
| toxic neuritis | Neuritis caused by an endogenous or exogenous toxin. (05 Mar 2000) |
| toxic psychosis | A psychosis caused by some toxic substance, whether endogenous or exogenous. (05 Mar 2000) |
| toxic retinopathy | Retinal changes due to prolonged administration of various drugs. (05 Mar 2000) |
| toxic shock | See toxic shock syndrome. (12 Dec 1998) |
| toxic shock syndrome | <syndrome> A blood-borne bacterial infection caused by the genus Staphylococcus. Usually effects menstruating females under the age of thirty and was associated in the past with the use of a particular type of tampon (no longer used). Common symptoms include: fever, chills, vomiting, sore throat, headache and decreased urine output. Progression of disease can result in lowering of blood pressure (shock) and renal failure. Treatment includes hospitalisation and intravenous antibiotics emergently. (27 Sep 1997) |
| toxic substances | A chemical or mixture of chemicals that presents a high risk of injury to human health or to the environment. (05 Dec 1998) |
| toxic tetanus | Tonic spasms caused by strychnine or other tetanic. Synonym: toxic tetanus. (05 Mar 2000) |
| toxic unit | A unit formerly synonymous with minimal lethal dose but which, because of the instability of toxins, is now measured in terms of the quantity of standard antitoxin with which the toxin combines. See: L doses, minimal lethal dose. Synonym: toxin unit. (05 Mar 2000) |
| endemic goiter | Goiter, usually of simple type, prevalent in certain regions where dietary intake of iodine is suboptimal. (05 Mar 2000) |