| zonal necrosis | Necrosis predominantly affecting or limited to an anatomical zone, especially parts of the hepatic lobules defined according to proximity to either the portal tracts or central (hepatic) veins. (05 Mar 2000) |
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| femur head necrosis | Aseptic or avascular necrosis of the femoral head. The major types are idiopathic (primary), as a complication of fractures or dislocations, and legg-perthes disease. (12 Dec 1998) |
| fibrinoid necrosis | Necrosis in which the necrotic tissue has some staining reactions resembling fibrin and becomes deeply eosinophilic, homogenous, and refractile. (05 Mar 2000) |
| focal necrosis | Occurrence of numerous, relatively small or tiny, fairly well-circumscribed, usually spheroidal portions of tissue that manifest coagulative, caseous, or gummatous necrosis and are characteristically associated with agents that are haematogenously disseminated; frequently observed only in histologic sections, but the foci may be as large as 1 to 3 mm and macroscopically visible; arbitrarily, foci larger than that are usually not termed focal necrosis. (05 Mar 2000) |
| laminar cortical necrosis | The breaking down of a definite cell layer in the cerebral cortex, encountered typically after temporary cardiac arrest or perinatal hypoxia. (05 Mar 2000) |
| liquefactive necrosis | A type of necrosis characterised by a fairly well-circumscribed, microscopically or macroscopically visible lesion that consists of the dull, opaque or turbid, gray-white to yellow-gray, soft or boggy, partly or completely fluid remains of tissue that became necrotic and was digested by enzymes, especially proteolytic enzymes liberated from disintegrating leukocytes; it is classically observed in abscesses, and frequently in infarcts of the brain. (05 Mar 2000) |
| abdominal wall fat pad biopsy | <investigation, procedure, surgery> The removal of a small specimen of the abdominal wall fat pad for microscopic examination. Often used in the diagnosis of amyloidosis. Performed with a local anaesthetic. (25 Jun 1999) |
| Bichat's fat-pad | An encapsuled mass of fat in the cheek on the outer side of the buccinator muscle, especially marked in the infant; supposed to strengthen and support the cheek during the act of sucking. Synonym: corpus adiposum buccae, Bichat's fat-pad, Bichat's protuberance, fat body of cheek, sucking cushion, sucking pad, suctorial pad. (05 Mar 2000) |
| brown fat | A thermogenic type of adipose tissue containing a dark pigment, and arising during embryonic life in certain specific areas in many mammals, including man. It is prominent in the newborn of all species in which it occurs and remains a distinct and conspicuous tissue in the adults of certain species, especially those that hibernate. It is also called brown adipose tissue. (12 Dec 1998) |
| brown fat cell | <pathology> Brown fat is specialised for heat production and the adipocytes have many mitochondria in which an inner membrane protein can act as an uncoupler of oxidative phosphorylation allowing rapid thermogenesis. (18 Nov 1997) |
| buccal fat-pad | An encapsuled mass of fat in the cheek on the outer side of the buccinator muscle, especially marked in the infant; supposed to strengthen and support the cheek during the act of sucking. Synonym: corpus adiposum buccae, Bichat's fat-pad, Bichat's protuberance, fat body of cheek, sucking cushion, sucking pad, suctorial pad. (05 Mar 2000) |
| chicken fat clot | Clot formed in vitro or postmortem from leukocytes and plasma of sedimented blood. (05 Mar 2000) |
| combined fat-and carbohydrate-induced hyperlipaemia | Hyperlipoproteinaemia characterised by increased plasma levels of chylomicrons, VLDL, pre-beta-lipoproteins, and triglycerides, and slight rise of cholesterol on a normal diet, with beta-lipoproteins normal; may be accompanied by bouts of abdominal pain, hepatosplenomegaly, susceptibility to atherosclerosis, and abnormal glucose tolerance; probably autosomal recessive inheritance. Synonym: combined fat-and carbohydrate-induced hyperlipaemia, familial hyperchylomicronaemia with hyperprebetalipoproteinaemia, mixed hyperlipaemia. (05 Mar 2000) |
| white fat | <anatomy> Connective tissue that has been specialised to store fat. See: adipocyte. (25 Jun 1999) |
| multilocular fat | A thermogenic type of adipose tissue containing a dark pigment, and arising during embryonic life in certain specific areas in many mammals, including man. It is prominent in the newborn of all species in which it occurs and remains a distinct and conspicuous tissue in the adults of certain species, especially those that hibernate. It is also called brown adipose tissue. (12 Dec 1998) |
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