| molecular mimicry | The process in which structural properties of an introduced molecule imitate or simulate molecules of the host. Direct mimicry of a molecule enables a viral protein to bind directly to a normal substrate as a substitute for the homologous normal ligand. Immunologic molecular mimicry generally refers to what can be described as antigenic mimicry and is defined by the properties of antibodies raised against various facets of epitopes on the viral protein. (12 Dec 1998) |
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| molecular modeling | <chemistry> The use of computers to create models of molecules. (14 Nov 1997) |
| molecular movement | Erratic, nondirectional, zigzag movement observed by ultramicroscope in certain colloidal solutions and by microscope in suspensions of light particulate matter that results from the jostling or bumping of the larger particles by the molecules in the suspending medium which are regarded as being in continuous motion. Synonym: brownian motion, brownian-Zsigmondy movement, molecular movement, pedesis. (05 Mar 2000) |
| molecular pathology | The study of biochemical and biophysical cellular mechanisms as the basic factors in disease. (05 Mar 2000) |
| molecular probes | A group of atoms or molecules attached to other molecules or cellular structures and used in studying the properties of these molecules and structures. Radioactive DNA or RNA sequences are used in molecular genetics to detect the presence of a complementary sequence by molecular hybridization. (12 Dec 1998) |
| molecular probe techniques | The use of devices which use detector molecules to detect, investigate, or analyze other molecules, macromolecules, molecular aggregates, or organisms. (12 Dec 1998) |
| molecular sequence data | Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as genbank, european molecular biology laboratory (embl), national biomedical research foundation (nbrf), or other sequence repositories. (12 Dec 1998) |
| molecular sieve | A gel-like material with pore sizes of such ranges as to exclude molecules above certain sizes; used in fractionating or purifying macromolecules. (05 Mar 2000) |
| molecular structure | The location of the atoms, groups or ions relative to one another in a molecule, as well as the number and location of chemical bonds. (12 Dec 1998) |
| molecular weight | The sum of the atomic weight's of all the atoms constituting a molecule; the mass of a molecule relative to the mass of a standard atom, now 12C (taken as 12.000). Relative molecular mass (Mr) is the mass relative to the dalton and has no units. See: atomic weight. Synonym: molecular mass, molecular weight ratio, relative molecular mass. (05 Mar 2000) |
| molecular weight ratio | The sum of the atomic weight's of all the atoms constituting a molecule; the mass of a molecule relative to the mass of a standard atom, now 12C (taken as 12.000). Relative molecular mass (Mr) is the mass relative to the dalton and has no units. See: atomic weight. Synonym: molecular mass, molecular weight ratio, relative molecular mass. (05 Mar 2000) |
| heparin, low-molecular-weight | <chemical> Heparin fractions with a molecular weight usually between 4000 and 6000 kD. These low-molecular-weight fractions are effective antithrombotic agents. Their administration reduces the risk of haemorrhage, they have a longer half-life, and their platelet interactions are reduced in comparison to unfractionated heparin. They also provide an effective prophylaxis against postoperative major pulmonary embolism. Pharmacological action: anticoagulant, fibrinolytic agent. (12 Dec 1998) |
| epidemiology, molecular | The application of molecular biology to the answering of epidemiological questions. The examination of patterns of changes in DNA to implicate particular carcinogens and the use of molecular markers to predict which individuals are at highest risk for a disease are common examples. (12 Dec 1998) |
| european molecular biology lab gene bank | <molecular biology> A large database of DNA sequence data in Heidelberg, Germany, compiled from international sources. It is the European equivalent to the Genbank DNA sequence databank in the United States of America. WWW: EMbase. (09 Oct 1997) |
| kininogen, high-molecular-weight | A plasma protein, molecular weight of 110 kD, that normally exists in plasma in a 1:1 complex with prekallikrein. Hmwk is split by plasma kallikrein to produce bradykinin. The complex is a cofactor in the activation of coagulation factor xii. The product of this reaction, xiia, in turn activates prekallikrein to kallikrein. (12 Dec 1998) |