| macroglobulin | <haematology, immunology> Globulin such as IgM that has a high molecular weight 400 kD in the case of IgM, 725 kD in the case of _ 2 macroglobulin. (18 Nov 1997) |
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| macroglobulinaemia | The presence of increased levels of macroglobulins in the circulating blood. Waldenstrom's macroglobulinaemia, macroglobulinaemia occurring in elderly persons, characterised by proliferation of cells resembling lymphocytes or plasma cells in the bone marrow, anaemia, increased sedimentation rate, and hyperglobulinaemia with a narrow peak in gamma-globulin or b2-globulin at about 19 S units. The spleen, liver, or lymph nodes are often enlarged and there is frequently purpura or mucosal bleeding. Synonym: hyperglobulinaemic purpura, Waldenstrom's purpura, Waldenstrom's syndrome. (05 Mar 2000) |
| macroglobulins | Serum globulins with high molecular weight. (12 Dec 1998) |
| macroglossia | Excessively large tongue. (27 Sep 1997) |
| macrognathia | Enlargement or elongation of the jaw. Synonym: megagnathia. Origin: macro-+ G. Gnathos, jaw (05 Mar 2000) |
| macrograph | <microscopy> A close-up photograph at a low magnification up to 40X or thereabouts. (05 Aug 1998) |
| macrography | Rarely used term for writing with very large letters. Synonym: megalographia. Origin: macro-+ G. Grapho, to write (05 Mar 2000) |
| macrogyria | Abnormal coarseness or largeness of the ridgelike folds of the cerebralcortex (the gyri). (09 Oct 1997) |
| macroinfauna | Animals living within aquatic sediments and large enough to be seen with the naked eye. (09 Oct 1997) |
| macroinvertebrate | An invertebrate animal (animal without a backbone) large enough to be seen without magnification. (09 Oct 1997) |
| macrolabia | Synonym: macrocheilia. Origin: macro-+ L. Labium, lip (05 Mar 2000) |
| macroleukoblast | An unusually large leukoblast. (05 Mar 2000) |
| macrolide | <pharmacology> A group of antibiotics produced by various strains of Streptomyces that have a complex macrocyclic structure. They inhibit protein synthesis by blocking the 50S ribosomal subunit. Include erythromycin, carbomycin. Used clinically as broad spectrum antibiotics, particularly against gram-positive bacteria. (18 Nov 1997) |
| macrolide 2'-kinase | <enzyme> Inducible intracellular enzyme which inactivates 14-member ring macrolides at the 2'-oh of the d-desosamine moiety; from an erythromycin-resistant strain of E coli; GTP, itp and ATP can also act as donors; mph(2')i is encoded by mpha and mrx, which have been sequenced Registry number: EC 2.7.1.136 Synonym: oleandomycin 2'-phosphotransferase, macrolide 2'-phosphotransferase, macrolide 2'-phosphotransferase I, mph(2')i (26 Jun 1999) |
| macrolide glycosyltransferase | <enzyme> From streptomyces lividans; utilises udp-glucose as cofactor; substrates include macrolides with 12-, 14-, 15-, or 16-atom cyclic polyketide lactones; enzyme specific for the 2'-oh group of saccharide moieties attached to c-5 of the 16-atom lactone ring Registry number: EC 2.4.1.- Synonym: macrolide glucosyltransferase (26 Jun 1999) |
| macrophage |
A large immune cell that devours invading pathogens and other intruders. Stimulates other immune cells by presenting them with small pieces of the invader. Macrophages can harbor large quantities of HIV without being killed, acting as reservoirs of the virus.
Ãâó: www.amfar.org/cgi-bin/iowa/bridge.html
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| macromolecule |
A large polymer such as DNA, RNA, protein, lipid or polysaccharide.
Ãâó: helios.bto.ed.ac.uk/bto/glossary/lm.htm
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| macrosomia |
Larger-than-normal birth weight (usually more than 9 ?pounds, or 4,500 grams).
Ãâó: www.bdid.com/termsm.htm
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| macrophage |
Large cells found throughout the body, particularly in the spleen, that have the ability to ingest other substances such as "old" red blood cells; also important in the immune response.
Ãâó: www.bdid.com/termsm.htm
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| macrocyclic |
Of rusts: The two primary spore stages are present (telial with teliospores and aecial with aeciospores). (8)
Ãâó: ppathw3.cals.cornell.edu/glossary/Defs_M.htm
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