| lymphocyte function associated antigen | A member of the integrin family that is expressed on all leukocytes and binds to ICAM-1 and ICAM-2 on a variety of cells. (05 Mar 2000) |
|---|---|
| lymphocyte function-associated antigen-1 | A heterodimer molecule widely expressed on cells of haematopoietic origin. Cd11a antigen comprises the alpha chain and the CD18 antigen (antigens, CD18) the beta chain. Lfa-1 is a major receptor of T-cells, B-cells, and granulocytes. It mediates the leukocyte adhesion reactions underlying cytolytic conjugate formation, helper T-cell interactions, and antibody-dependent killing by natural killer cells and granulocytes. Intracellular adhesion molecule-1 (icam-1) has been defined as a ligand for lfa-1. (12 Dec 1998) |
| lymphocyte-oriented kinase | <enzyme> An ste20-like protein kinase; genbank d89728 Registry number: EC 2.7.10.- Synonym: lok gene product (26 Jun 1999) |
| lymphocyte specific protein tyrosine kinase p56(lck) | <enzyme> This enzyme is a lymphoid specific src family tyrosine kinase that is critical for T-cell development and activation. Lck is associated with the cytoplasmic domains of CD4, CD8 and the beta-chain of the il-2 receptor, and is thought to be involved in the earliest steps of tcr-mediated T-cell activation. Registry number: EC 2.7.11.- (12 Dec 1998) |
| lymphocyte subsets | A classification of lymphocytes based on structurally or functionally different populations of cells. (12 Dec 1998) |
| lymphocyte transformation | <haematology> The change in morphology and behaviour of lymphocytes exposed to a mitogen or to an antigen to which they have been primed. The result is the production of lymphoblasts, cells that are actively engaged in protein synthesis and that divide to form effector populations. Should not be confused with transformation of the type associated with oncogenic viruses and activation is therefore perhaps a better term. (18 Nov 1997) |
| lymphocyte transfusion | The transfer of lymphocytes from a donor to a recipient or reinfusion to the donor. (12 Dec 1998) |
| cellular immune theory | A concept, put forth by Elie Metchnikoff, that cells, not antibodies, were responsible for the immune response of an organism. (05 Mar 2000) |
| primary immune response | <immunology> The immune response to the first challenge by a particular antigen. Usually less extensive than the secondary immune response, being slower and shorter lived with smaller amounts of lower affinity antibody being produced. (18 Nov 1997) |
| hemic and immune systems | The organs involved in the production and functions of the blood and the cellular and molecular components providing defense against foreign organisms or substances. (12 Dec 1998) |
| secondary immune response | The response of the immune system to the second or subsequent occasion on which it encounters a specific antigen. (18 Nov 1997) |
| human measles immune serum | Obtained from the blood of a healthy person who has survived an attack of measles. Synonym: measles convalescent serum. (05 Mar 2000) |
| human pertussis immune serum | The sterile serum prepared from the pooled blood of healthy adult human beings who have received repeated courses of phase I pertussis vaccine; administered intravenously or intramuscularly for the prophylaxis or treatment of whooping cough. (05 Mar 2000) |
| human scarlet fever immune serum | Scarlet fever convalescent serum, obtained from healthy persons who have survived an attack of scarlet fever. (05 Mar 2000) |
| humoral immune response | <immunology> Those immune responses mediated by antibody. (06 Mar 1998) |