| Robison ester dehydrogenase | <enzyme> An NADP+ enzyme that catalyses the dehydrogenation (oxidation) of d-glucose-6-phosphate to 6-phospho-d-glucono-d-lactone, this reaction initiating the Dickens shunt. Deficiency of this enzyme is the commonest disease-causing enzyme defect in humans affecting an estimated 400 million people. The gene for this enzyme is on the X chromosome. Males with the enzyme deficiency develop haemolytic anaemia when red blood cells are exposed to oxidant drugs such as the antimalarial primaquine, the sulfonamide antibiotics or sulfones, naphthalene moth balls, or fava beans. Synonym: Robison ester dehydrogenase, Zwischenferment. Acronym: G6PD (12 Sep 2002) |
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| methoxyneurosporene dehydrogenase | <enzyme> From rhodobacter sphaeroides; involved in later stages of carotenoid biosynthesis Registry number: EC 1.- Synonym: crtd gene product (26 Jun 1999) |
| methylamine dehydrogenase | <enzyme> Forms formaldehyde and hydrogen peroxide; paracoccus denitrificans contains covalently bound pyrroloquinoline quinone as prosthetic group Registry number: EC 1.4.99.- Synonym: methylamine oxidase, quinoprotein methylamine dehydrogenase, madh, mau gene product, methylamine utilization gene product (26 Jun 1999) |
| methylenetetrahydrofolate dehydrogenase | <enzyme> Catalyses the oxidation of methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate. Includes EC 1.5.1.15 which uses NAD+. Chemical name: 5,10-Methylenetetrahydrofolate:NADP+ oxidoreductase Registry number: EC 1.5.1.5 (12 Dec 1998) |
| methylene tetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase | <chemical> Bifunctional enzyme which contains mg-nad dependent covalently linked methylenetetrahydrofolate dehydrogenase (EC 1.5.1.15) and methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9); usually found in prokaryotes Synonym: methf dehydrogenase-cyclohydrolase (26 Jun 1999) |
| methylenetetrahydromethanopterin dehydrogenase | <enzyme> Dependent on coenzyme f420; forms methenyltetrahydromethanopterin Registry number: EC 1.5.99.- Synonym: me-h4mpt dehydrogenase, 5,10-methylenetetrahydromethanopterin reductase, n(5),n(10)-methylenetetrahydromethanopterin reductase, coenzyme f(420)-dependent methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase, cof(420)-dependent methylenetetrahydromethanopterin dehydrogenase, mtd protein, h2-dependent methylene-h4mpt dehydrogenase, mth protein, cofactor f420-independent me-h4mpt dehydrogenase (26 Jun 1999) |
| methylglyoxal dehydrogenase | <enzyme> Oxidises methylglyoxal to pyruvate; requires nad Registry number: EC 1.2.1.- (26 Jun 1999) |
| phenylacetaldehyde dehydrogenase | <enzyme> From E coli; catalyses the oxidation of phenylacetaldehyde to phenylacetic acid in the presence of nad+ Registry number: EC 1.2.1.39 Synonym: phenylacetaldehyde-nad+ oxidoreductase (26 Jun 1999) |
| cinnamyl alcohol dehydrogenase | <enzyme> Nadp-dependent Registry number: EC 1.1.1.195 Synonym: cad2 protein (26 Jun 1999) |
| cis-1,2-dihydrobenzene-1,2-diol dehydrogenase | <enzyme> See also EC 1.3.1.20 (trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; both enzymes catalyze the conversion of benzene dihydrodiol to catechol and may also have hydroxysteroid dehydrogenase activity Chemical name: cis-1,2-dihydroxycyclohexa-3,5-diene (nad) oxidoreductase Registry number: EC 1.3.1.19 Synonym: cis-benzene glycol dehydrogenase, cis-diol dehydrogenase, benzene dihydrodiol dehydrogenase, bedd gene product, nad+-dependent cis-benzene dihydrodiol dehydrogenase, todd gene product (26 Jun 1999) |
| phosphogluconate dehydrogenase | <enzyme> An enzyme of the oxidoreductase class that catalyses the reaction 6-phospho-d-gluconate and NADP+ to yield d-ribulose 5-phosphate, carbon dioxide, and NADPH. The reaction is a step in the pentose phosphate pathway of glucose metabolism. Chemical name: 6-Phospho-D-gluconate:NAD(P)+ 2-oxidoreductase Registry number: EC 1.1.1.43 (12 Dec 1998) |
| cis-toluene dihydrodiol dehydrogenase | <enzyme> Nad specific dehydrogenase; reduces ring structure Chemical name: 1,2-dihydroxy-3-methylcyclohexa-3,5-diene dehydrogenase Registry number: EC 1.3.- Synonym: ctd dehydrogenase (26 Jun 1999) |
| phosphoglycerate dehydrogenase | <enzyme> Catalyses the oxidation of 3-phosphoglyceric acid to 3-phosphohydroxy pyruvate, which can be transaminated and then hydrolyzed to give serine; minor descriptor (75-85); on-line and index medicus search alcohol oxidoreductases (75-77) and carbohydrate dehydrogenases (78-85) Registry number: EC 1.1.1.95 Synonym: phosphoglycerate oxidoreductase, 3-phosphoglycerate-nad+ 2-oxidoreductase, 3-phosphoglycerate dehydrogenase, sera gene product (26 Jun 1999) |
| phytoene dehydrogenase | <enzyme> Phytoene is oxidised to phytofluene; has been sequenced; genbank d83514 Registry number: EC 1.- Synonym: phytoene desaturase, carotenoid desaturase, crti gene product, carc gene product, carb gene product (26 Jun 1999) |
| coenzyme F420-dependent alcohol dehydrogenase | <enzyme> From methanogenium liminatans; catalyses oxidation of various secondary and cyclic alcohols to the corresponding ketones and the reverse reaction Registry number: EC 1.1.99.- Synonym: f(420) alcohol dehydrogenase (26 Jun 1999) |