| Mo-MLV | Moloney murine leukemia virus |
|---|---|
| Mo-MSV | Moloney murine sarcoma virus |
| MOS | medial orbital sulcus; Medical Outcomes Study; microsomal ethanol-oxidizing system; Moloney murine s... |
| MSV | maximum sustained level of ventilation; mean scale value; mean spatial velocity; Moloney sarcoma vir... |
| MuLV, MuLv | murine leukemia virus |
| enteric viruses | Virus's of the genus Enterovirus. (05 Mar 2000) |
|---|---|
| Koongol viruses | A serologic group of the genus Bunyavirus, comprising two species, Koongol (type species) and Wongal virus. (05 Mar 2000) |
| fibrous bacterial viruses | Deoxyribonucleoproteins that "infect" and replicate in Gram-negative bacteria having sex pili and that, unlike bacteriophage, are released from infected bacteria without damage to the cell; they seem to be of two kinds, one of which has a specificity for F pili and the other for I pili. Synonym: fibrous bacterial viruses. (05 Mar 2000) |
| filamentous bacterial viruses | Deoxyribonucleoproteins that "infect" and replicate in Gram-negative bacteria having sex pili and that, unlike bacteriophage, are released from infected bacteria without damage to the cell; they seem to be of two kinds, one of which has a specificity for F pili and the other for I pili. Synonym: fibrous bacterial viruses. (05 Mar 2000) |
| uukuniemi group viruses | A group of viruses in the genus phlebovirus of the family bunyaviridae, infecting vertebrates and vectored by ticks. Its members have not been associated with human disease though antibodies have been isolated from human sera. (12 Dec 1998) |
| foamy viruses | Retroviruses of the subfamily Spumavirinae, found in primates and other mammals; so named because of lacelike changes produced in monkey kidney cells; syncytia are also produced. Synonym: foamy agents. (05 Mar 2000) |
| lcm-lassa complex viruses | One of two groups of viruses in the arenavirus genus and considered part of the old world complex. It includes lassa virus and lymphocytic choriomeningitis virus, although the latter has worldwide distribution now. (12 Dec 1998) |
| abelson leukaemia virus | A defective murine leukaemia virus capable of transforming lymphoid cells and producing a rapidly progressing lymphoid leukaemia after superinfection with friend, moloney, or rauscher virus. (12 Dec 1998) |
| accelerated phase of leukaemia | Refers to chronic myelogenous leukaemia that is progressing. The number of immature, abnormal white blood cells in the bone marrow and blood is higher than in the chronic phase, but not as high as in the blast phase. (12 Dec 1998) |
| acute granulocytic leukaemia | <haematology> A form of leukaemia which is characterised by the proliferation of immature white blood cells (granulocytes) in the bloodstream. Occurs primarily in adults and in infants under 1 year of age. Complications include abnormal bleeding and susceptibility to infections. Symptoms include fatigue, weight loss, fevers, weakness, pallor, bone pains, bleeding gums, nosebleeds, easy bruising, enlarged lymph nodes and joint pains. Treatment includes chemotherapy and/or bone marrow transplant. Origin: Gr. Haima = blood (27 Sep 1997) |
| acute leukaemia | <haematology> A rapidly progressive cancer of the blood of sudden onset and characterised by the uncontrolled proliferation of immature blood cells which take over the bone marrow and spill into the blood stream. If left untreated is fatal within a few weeks or months. See: acute lymphoblastic leukaemia, acute myeloid leukaemia. Origin: Gr. Haima = blood (11 Nov 1997) |
| acute lymphoblastic leukaemia | <haematology> A rapidly progressing cancer of the blood affecting the type of white blood cell known as lymphocytes. Approximately 650 new cases are diagnosed every year in the UK and it is the most common form of childhood leukaemia. Acronym: ALL Origin: Gr. Haima = blood (11 Nov 1997) |
| acute lymphocytic leukaemia | <radiology> 95% of cases of leukaemia in children, bone changes in 50-70% of kids (vs. 10% in adults); seen as early as 1 month after onset of symptoms, wrists and knees most commonly affected, bony defects: metaphyseal radiolucent bands! (similar findings in scurvy, JRA, syphilis), osteolytic lesions, periosteal reaction, osteosclerosis (12 Dec 1998) |
| acute monocytic leukaemia | <haematology> The most common translocation in this disorder of poorly differentiated monocytic cells involves chromosome region 11q in a large percentage of cases. The translocation involves a cellular oncogene, c-ets which is mapped to the 11q23-24 region. The most common translocations reported are t(6;11), t(9;11), t(11;17) and t(11;19), of which t(9;11) (p21-22;q23) is by far the most frequently detected and implicated in acute myeloid leukaemia. The cells express CD14 surface antigen, which is diagnostic of monocytic cells. Acronym: AML Classification: FAB M5 (07 Apr 1998) |
| acute myeloblastic leukaemia | <haematology> A rapidly progressing cancer of the blood affecting immature cells of the bone marrow, usually of the white cell population. It is much more common in adults than in children. Symptoms include fatigue, weight loss, fevers, weakness, pallor, bone pains, bleeding gums, nosebleeds, easy bruising, enlarged lymph nodes and joint pains. Treatment includes chemotherapy and/or bone marrow transplant. This leukaemia demonstrates granulocyte differentiation, eosinophilia and Auer rods and is associated with a reciprocal translocation between 8 and 21 (q22;q22), which is the most common translocation in acute myeloid leukaemia and is found more often in younger patients than in older patients. The oncogene involved in this translocation is AML1, which can be detected by Southern blot. Numerical abnormalities, particularly monosomy-7, trisomy-4, trisomy-8, trisomy-21, -Y, monosomy-7 and deletions of the long arms of chromosomes 5 and 7 are quite common in all acute myeloid leukaemia and not restricted to any one FAB classification. Many of these abnormalities are observed at diagnosis and at later stage disease, particularly after chemotherapy. Prognosis is generally more favorable than in FAB-M2 patients showing no translocation, because the latter patients show better remission rates for longer periods of time. Immunophenotyping is useful in diagnosis and expression of one or more of the myeloid antigens CD13, CD14 or CD33 must be detected to make a diagnosis of acute myeloid leukaemia. Acronym: AML Incidence: 2,000 new cases per year in the UK. Origin: Gr. Haima = blood (07 Apr 1998) |