| immunization, secondary | Any immunization following a primary immunization and involving exposure to the same or a closely related antigen. (12 Dec 1998) |
|---|---|
| immunization, serum hepatitis | See Immunization, hepatitis b. (12 Dec 1998) |
| immunization, varicella zoster | See Immunization, chickenpox. (12 Dec 1998) |
| immuno- | Immune, immunity. Origin: L. Immunis, immune (05 Mar 2000) |
| immunoadjuvant | See: adjuvant. (05 Mar 2000) |
| immunoadsorbent | <chemistry> Any insoluble material for example cellulose, with either an antigen or an antibody bound to it and that will bind its corresponding antibody or antigen thus removing it from a solution. (18 Nov 1997) |
| immunoagglutination | Specific agglutination effected by antibody. (05 Mar 2000) |
| immunoassay | <investigation> A process that measures and identifies a specific biological substance such as an antigen. (09 Oct 1997) |
| immunobiology | The study of the immune factors that affect the growth, development, and health of biological organisms. (05 Mar 2000) |
| immunoblast | An antigenically stimulated lymphocyte; a large cell with well-defined basophilic cytoplasm, a large nucleus with prominent nuclear membrane, distinct nucleoli, and clumped chromatin. See: lymphocyte transformation. Origin: immuno-+ G. Blastos, germ (05 Mar 2000) |
| immunoblastic lymphadenopathy | A disorder characterised by proliferation of arborizing small vessels, prominent immunoblastic proliferations and amorphous acidophilic interstitial material. Clinical manifestations include fever, sweats, weight loss, generalised lymphadenopathy and frequently hepatosplenomegaly. (12 Dec 1998) |
| immunoblastic lymphoma | <tumour> A monomorphous proliferation of immunoblasts involving the lymph nodes; it may develop in some patients with angioimmunoblastic lymphadenopathy. (05 Mar 2000) |
| immunoblastic sarcoma | <tumour> Obsolete term for immunoblastic lymphoma. (05 Mar 2000) |
| immunoblot | Commonly referred to as Western blot because of the similarity to the procedures described above, is used to detect antibodies to specific epitopes of electrophoretically separated subspecies of antigens. Electrophoresis of antigenic material yields separation of the antigenic components by molecular weight. Blotting of the separated antigen to nitrocellulose, retaining the electrophoretic position, and reacting it with patient specimen will result in the binding of specific antibodies, if present, to each antigenic "band". Electrophoresis of known molecular weight standards allows for the determination of the molecular weight of each antigenic band to which antibodies may be produced. These antibodies are then detected using EIA reactions which characterise antibody specificity. This technique is often used to confirm the specificity of antibodies which are detected by ELISA screening procedures. (05 Mar 2000) |
| immunoblotting | <technique> Very small amounts of protein are transferred from gels to nitrocellulose sheets by electrophoresis and then detected by their antibody binding, usually in combination with peroxidase or radioactively labelled IgG. An accurate technique for the specific recognition of very small amounts of protein. (13 Oct 1997) |