| idiopathic disease | A disease of unknown cause or mechanism. (05 Mar 2000) |
|---|---|
| idiopathic epilepsy | An epilepsy without evident cause; term often used to describe the genetic epilepsies. Synonym: generalised tonic-clonic seizure. (05 Mar 2000) |
| idiopathic fibrous hyperplasia | A condition of cystic bone growth that results from abnormal bone development. May occur with bone lesions, skin pigmentation and endocrine abnormalities. See: McCune-Albright syndrome. Origin: Gr. Plassein = to form (27 Sep 1997) |
| idiopathic fibrous mediastinitis | <radiology> Histoplasmosis most common cause, can cause superior vena cava obstruction (12 Dec 1998) |
| idiopathic fibrous retroperitonitis | <radiology> Ureters tapered or obstructed, most severe at L4-5, ureters deviated medially, Treatment: symptomatic; steroids have ? long-term benefit Differential diagnosis: malignancy, lymphoma (especially Hodgkin's), metastasis from colon and breast, retroperitoneal sarcoma, drugs, methysergide (Sansert), haemorrhage, aortic aneurysm, trauma or surgery, inflammation, Crohn's disease, diverticulitis, pancreatitis, extravasated urine, radiation (12 Dec 1998) |
| idiopathic gout | Acute episodes of crystal-induced synovitis due to abnormality of purine metabolism; lower than normal urinary excretion of urate leading to hyperuricaemia and acute episodes of joint inflammation. Synonym: primary gout. Interval gout, an asymptomatic phase between acute attacks of gout. Latent gout, hyperuricaemia without symptoms of gout. Often used synonymously with interval gout. Synonym: masked gout. (05 Mar 2000) |
| idiopathic hirsutism | Hirsutism of uncertain origin in women, who may additionally exhibit menstrual abnormalities and infertility. (05 Mar 2000) |
| idiopathic hypercalcaemic sclerosis of infants | See: idiopathic hypercalcaemia of infants. (05 Mar 2000) |
| idiopathic hyperlipaemia | Hyperlipoproteinaemia characterised by the presence of large amounts of chylomicrons and triglycerides in the plasma when the patient has a normal diet, and their disappearance on a fat-free diet; low alpha-and beta-lipoproteins on a normal diet, with increase on fat-free diet; decreased plasma postheparin lipolytic activity; and low tissue lipoprotein lipase activity. It is accompanied by bouts of abdominal pain, hepatosplenomegaly, pancreatitis, and eruptive xanthomas; autosomal recessive inheritance. See: familial lipoprotein lipase inhibitor. Synonym: Burger-Grutz syndrome, familial fat-induced hyperlipaemia, familial hyperchylomicronaemia, familial hypertriglyceridemia, idiopathic hyperlipaemia. (05 Mar 2000) |
| idiopathic hypertension | Hypertension without known cause. Synonym: idiopathic hypertension, primary hypertension. (05 Mar 2000) |
| idiopathic hypertrophic subaortic stenosis | <cardiology> A congenital heart disease that results in abnormal thickening of the ventricular septum and left ventricular wall. Enlargement of the ventricular septum can result in ventricular outflow obstruction (subaortic stenosis) and eventual cardiomyopathy. (27 Sep 1997) |
| idiopathic hypoparathyroidism | <radiology> Rare condition of unknown cause, round face; short dwarf-like; obese, mental retardation, cataracts, dry scaly skin; atrophy of nails, dental hypoplasia (delayed tooth eruption, impaction of teeth, supernumerary teeth) see: hypoparathyroidism (12 Dec 1998) |
| idiopathic infantilism | Dwarfism generally associated with hypogonadism; may be caused by deficient secretion of anterior pituitary hormones. Synonym: Lorain's disease, proportionate infantilism, universal infantilism. (05 Mar 2000) |
| idiopathic interstitial fibrosis | A progressive inflammatory condition starting with diffuse alveolar damage and resulting in fibrosis and honeycombing over a variable time period; also a common feature of collagen-vascular diseases. Synonym: fibrosing alveolitis, Hamman-Rich syndrome, idiopathic interstitial fibrosis. (05 Mar 2000) |
| idiopathic megacolon | An acquired megacolon, found in children and adults, without distal obstruction or absence of ganglion cells; the muscle of the dilated colon is thin. (05 Mar 2000) |