| hepatitis B core a. |
a core protein antigen of the hepatitis B virus present inside complete virions (Dane particles) and in the nuclei of infected hepatocytes, indicating the presence of replicating hepatitis B virus; the antigen is not present in the blood of infected individuals, but anti-HBc antibodies appear during the acute infection; they do not protect against reinfection.
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| hepatitis B e a. |
an antigen of hepatitis B virus sometimes present in the blood during acute infection, usually disappearing afterward but sometimes persisting in chronic disease. Anti-HBe antibodies appear transiently during convalescence; they do not protect against reinfection.
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| hepatitis B immune g. |
[USP] a specific immune globulin derived from plasma of human donors with high titers of antibodies against hepatitis B surface antigen (HBsAg); used for postexposure prophylaxis following contact with HBsAg-positive materials, also administered to infants of HBsAg-positive mothers.
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| hepatitis B surface a. |
a coat protein antigen of the hepatitis B virus present on complete virions (Dane particles) and smaller spherical and filamentous particles circulating in the blood of individuals with active or chronic infections, being first detectable several weeks prior to clinical disease and peaking with the appearance of symptoms. Anti-HBs antibodies appear in the blood in late convalescence and are protective against reinfection. Originally called Australia or Au antigen because it was first found in an Australian aborigine; also formerly called hepatitis-associated a. (HAA) and serum hepatitis (SH) a. See hepatitis B vaccine inactivated and hepatitis B vaccine (recombinant), under vaccine.
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| hepatitis B v. |
a virus of the genus Orthohepadnavirus that is the etiologic agent of hepatitis B.
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