| heparan-α-glucosaminide N- |
[EC 2.3.1.78] a lysosomal enzyme of the transferase class that catalyzes the acetylation of the amino groups of terminal desulfated glucosamine residues in heparan sulfate chains, a step in the degradation of heparan sulfate. Acetyl coenzyme A is the acetyl donor. Deficiency of the enzyme, an autosomal recessive trait, results in Sanfilippo's syndrome, type C. Called also acetyl CoA:α-glucosaminide N-acetyltransferase.
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| heparin c. II |
a member of the serpin (serine proteinase inhibitor) group; it is a single-chain glycoprotein, Mr 65,000, that inhibits thrombin. It resembles antithrombin III in being markedly stimulated by heparin; it differs in that it binds and is activated by dermatan sulfate and in that it does not inhibit any other activated coagulation factors.
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| heparin lock flush s. |
[USP] a sterile preparation of heparin sodium injection with sufficient sodium chloride to make it isotonic with blood, used to maintain patency of indwelling intravascular devices designed for intermittent injection or infusion therapy or blood sampling.
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| heparin r. |
the return of anticoagulant activity following the complete neutralization of heparin in a patient's blood by protamine.
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| heparinate |
any salt of heparin.
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