| SGPT | serum glutamate pyruvate transaminase (alanine aminotransferase) |
|---|---|
| SPG | serine phosphoglyceride; spastic paraplegia; splenoportography; sucrose, phosphate, and glutamate; s... |
| ALDH | ALdehyde DeHydrogenase = ADH |
| DH | 1) Diffuse Histiocytic 2) DeHydrogenase |
| G6PD, G6PD, G-6-PD | Glucose 6 Phosphate Dehydrogenase |
| glucose-6-dehydrogenase deficiency | <biochemistry> An inherited condition that results in a deficiency in glucose-6-phosphate dehydrogenase. Particular drugs (sulphonamides) can exacerbate this problem. The result is haemolytic anaemia. (27 Sep 1997) |
|---|---|
| glucose-6-phosphate dehydrogenase | <enzyme> An NADP+ enzyme that catalyses the dehydrogenation (oxidation) of d-glucose-6-phosphate to 6-phospho-d-glucono-d-lactone, this reaction initiating the Dickens shunt. Deficiency of this enzyme is the commonest disease-causing enzyme defect in humans affecting an estimated 400 million people. The gene for this enzyme is on the X chromosome. Males with the enzyme deficiency develop haemolytic anaemia when red blood cells are exposed to oxidant drugs such as the antimalarial primaquine, the sulfonamide antibiotics or sulfones, naphthalene moth balls, or fava beans. Synonym: Robison ester dehydrogenase, Zwischenferment. Acronym: G6PD (12 Sep 2002) |
| glucose-6-phosphate dehydrogenase deficiency | A deficiency of glucose-6-phosphate dehydrogenase, an enzyme important for maintaining cellular concentrations of reduced nucleotides. Deficiency of this enzyme is the commonest disease-causing enzyme defect in humans affecting an estimated 400 million people. The gene for this enzyme is on the X chromosome and there are various polymorphic forms. Males with the enzyme deficiency develop haemolytic anaemia when red blood cells are exposed to oxidant drugs such as the antimalarial primaquine, the sulfonamide antibiotics or sulfones, naphthalene moth balls, or fava beans. It can also cause anaemia of the newborn, and chronic nonspherocytic haemolytic anaemia. Inheritance: X-linked. (12 Sep 2002) |
| glucose dehydrogenase | <enzyme> Converts beta-d-glucose to d-glucono-d-lactone, transferring hydrogen to NAD+ or NADP+. Compare: glucose oxidase. (05 Mar 2000) |
| glucosephosphate dehydrogenase | <enzyme> Chemical name: D-Glucose-6-phosphate:NADP+ 1-oxidoreductase Registry number: EC 1.1.1.49 (12 Dec 1998) |
| glucosephosphate dehydrogenase deficiency | A disease-producing enzyme deficiency subject to many variants, some of which cause a deficiency of enzyme activity in erythrocytes, leading to haemolytic anaemia. (12 Dec 1998) |
| glutamyl tRNA dehydrogenase | <enzyme> Converts alpha carboxyl of glutamyl-trna to glutamate-1-saemialdehyde in the presence of NADPH Registry number: EC 1.2.1.- (26 Jun 1999) |
| glutaryl-CoA dehydrogenase | <enzyme> Glutaric aciduria may be due to deficiency of this enzyme Registry number: EC 1.3.99.7 Synonym: glutaryl CoA dehydrogenase, glutaryl-coenzyme a dehydrogenase (26 Jun 1999) |
| medium-chain acyl-CoA dehydrogenase | <enzyme> Deficiency in mitochondrial beta oxidation of fatty acids gives a disorder frequently masquerading as reye syndrome or sudden infant death; leads to buildup of octanoyl carnitine in urine Registry number: EC 1.3.- Synonym: mcaca-dehydrogenase, medium-chain acyl-coenzyme a dehydrogenase, octanoyl-CoA dehydrogenase, mcad enzyme (26 Jun 1999) |
| glyceraldehyde 3-phosphate dehydrogenase | <biochemistry> In glycolysis, this enzyme catalyses the conversion of glyceraldehyde 3-phosphate and organic phosphate and NAD+ into 1,3-bisphosphoglycerate and NADH and free hydrogens (and viceversa) by transferring hydrogens and electrons between the molecules. (09 Oct 1997) |
| glyceraldehydephosphate dehydrogenase | <enzyme> Chemical name: D-Glyceraldehyde-3-phosphate:NADP+ oxidoreductase Registry number: EC 1.2.1.9 (12 Dec 1998) |
| glycerol-1-phosphate dehydrogenase | <enzyme> From the archaebacterium methanobacterium thermoautotrophicum; forms the glycerophosphate which is the mirror image of that found in eubacterial and eukaryotic ether phospholipids Registry number: EC 1.1.1.- Synonym: sn-glycerol-1-phosphate - nad+ oxidoreductase, sn-g-1-p dehydrogenase (26 Jun 1999) |
| glycerol-3-phosphate dehydrogenase | Alpha-Glycerol phosphate dehydrogenase; 3-phosphoglycerol dehydrogenase;an oxidoreductase that catalyses the interconversion of dihydroxyacetone phosphate and sn-glycerol 3-phosphate, with the participation of NAD+; its action provides the glycerol moiety from carbohydrate during lipogenesis. (05 Mar 2000) |
| glycerolphosphate dehydrogenase | <enzyme> Registry number: EC 1.1.- (12 Dec 1998) |
| glycine dehydrogenase | Enzymes that catalyze the conversion of glycine to glyoxylate and ammonia, using either NAD+ or ferricytochrome c. (05 Mar 2000) |