| brephoplastic graft | A graft from an embryo or newborn to an adult. (05 Mar 2000) |
|---|---|
| bypass graft | <surgery> An alternative blood vessel that is created by a surgeon to reroute blood flow. Grafts may be synthetic (dacryon) or autologous (a vein from the patients own leg used as a substitute for the diseased vessel). (20 Mar 1998) |
| cable graft | A multiple strand nerve graft arranged as a pathway for regeneration of axons. (05 Mar 2000) |
| vascularised graft | The state of a graft after the recipient vasculature has been connected with the vessels in the graft. (05 Mar 2000) |
| partial-thickness graft | A graft of portions of the skin, i.e., the epidermis and part of the dermis, or of part of the mucosa and submucosa, but not including the periosteum. Synonym: partial-thickness graft, split-skin graft. (05 Mar 2000) |
| pedicle graft | A skin flap sustained by a blood-carrying stem from the donor site during transfer, in periodontal surgery, a flap used to increase the width of attached gingiva, or to cover a root surface, by moving the attached gingiva, which remains joined at one side, to an adjacent position and suturing the free end. (05 Mar 2000) |
| Reverdin graft | Small bits of skin, of partial or full thickness, removed from a healthy area and seeded in a site to be covered. Synonym: Reverdin graft. (05 Mar 2000) |
| graft | To insert scions from one tree, or kind of tree, etc, into another; to practice grafting. A small shoot or scion of a tree inserted in another tree, the stock of which is to support and nourish it. The two unite and become one tree, but the graft determines the kind of fruit. A branch or portion of a tree growing from such a shoot. <surgery> A portion of living tissue used in the operation of autoplasty. Origin: OE. Graff, F. Greffe, originally the same word as OF. Grafe pencil, L. Graphium, Gr, fr. To write; prob. Akin to E. Carve. So named from the resemblance of a scion or shoot to a pointed pencil. Cf. Graphic, Grammar. 1. To insert (a graft) in a branch or stem of another tree; to propagate by insertion in another stock; also, to insert a graft upon. [Formerly written graff. 2. <surgery> To implant a portion of (living flesh or akin) in a lesion so as to form an organic union. 3. To join (one thing) to another as if by grafting, so as to bring about a close union. "And graft my love immortal on thy fame !" (Pope) 4. To cover, as a ring bolt, block strap, splicing, etc, with a weaving of small cord or rope-yarns. Origin: F. Greffer. See Graft. Source: Websters Dictionary (01 Mar 1998) |
| graft enhancement, immunologic | The induction of prolonged survival and growth of allografts of either tumours or normal tissues which would ordinarily be rejected. It may be induced passively by introducing graft-specific antibodies from previously immunised donors, which bind to the graft's surface antigens, masking them from recognition by T-cells; or actively by prior immunization of the recipient with graft antigens which evoke specific antibodies and form antigen-antibody complexes which bind to the antigen receptor sites of the T-cells and block their cytotoxic activity. (12 Dec 1998) |
| graft occlusion | <physiology> Obstruction of flow in biological or prosthetic vascular grafts. (12 Dec 1998) |
| graft rejection | <haematology, immunology> When donated bone marrow infused during a bone marrow transplant is rejected by the patients body or does not take. (16 Dec 1997) |
| graft survival | <haematology> The survival of a graft in a host, the factors responsible for the survival and the changes occurring within the graft during growth in the host. (12 Dec 1998) |
| graft-versus-host disease | <haematology> A common and serious, complication of bone marrow transplantation where there is a reaction of donated bone marrow against a patient's own tissue. When donor lymphocytes or a graft containing lymphocytes that are immunologically competent are given to a patient that has low immunological competence, an incompatibility reaction can result. This is due to antibodies from the donor against antigens in the host. This is due to mismatch of MHC Class I antigens and can produce lymphocyte clones that will react by a variety of processes against the host and cause damage. The clinical condition can be fatal and is due to the donor's immune cells recognising the host cells as foreign. The clinical entity characterised by anorexia, diarrhoea, loss of hair, leukopenia, thrombocytopenia, growth retardation, and eventual death brought about by the graft-versus-host reaction. It can occur in either chronic or acute forms and is treatable by immunosuppressive drugs. Seen most commonly following bone marrow transplantation, acute disease is seen after 5-40 days and chronic disease weeks to months after transplantation, affecting, principally, the gastrointestinal tract, liver, and skin. Radiological appearances of the gastrointestinal tract include; thickened wall, mucosal folds thickened or effaced, increased secretions most likely to be rapid transit of GI tract, mass most likely to be focal oedema, fibrosis, hallmark: diffuse, uniform thickening of small bowel. Synonym: GVH disease. Acronym: GVHD (20 Sep 2002) |
| graft-versus-host reaction | <haematology> A common and serious, complication of bone marrow transplantation where there is a reaction of donated bone marrow against a patient's own tissue. When donor lymphocytes or a graft containing lymphocytes that are immunologically competent are given to a patient that has low immunological competence, an incompatibility reaction can result. This is due to antibodies from the donor against antigens in the host. This is due to mismatch of MHC Class I antigens and can produce lymphocyte clones that will react by a variety of processes against the host and cause damage. The clinical condition can be fatal and is due to the donor's immune cells recognising the host cells as foreign. The clinical entity characterised by anorexia, diarrhoea, loss of hair, leukopenia, thrombocytopenia, growth retardation, and eventual death brought about by the graft-versus-host reaction. It can occur in either chronic or acute forms and is treatable by immunosuppressive drugs. Seen most commonly following bone marrow transplantation, acute disease is seen after 5-40 days and chronic disease weeks to months after transplantation, affecting, principally, the gastrointestinal tract, liver, and skin. Radiological appearances of the gastrointestinal tract include; thickened wall, mucosal folds thickened or effaced, increased secretions most likely to be rapid transit of GI tract, mass most likely to be focal oedema, fibrosis, hallmark: diffuse, uniform thickening of small bowel. Synonym: GVH disease. Acronym: GVHD (20 Sep 2002) |
| graft-versus-host response | <haematology> A common and serious, complication of bone marrow transplantation where there is a reaction of donated bone marrow against a patient's own tissue. When donor lymphocytes or a graft containing lymphocytes that are immunologically competent are given to a patient that has low immunological competence, an incompatibility reaction can result. This is due to antibodies from the donor against antigens in the host. This is due to mismatch of MHC Class I antigens and can produce lymphocyte clones that will react by a variety of processes against the host and cause damage. The clinical condition can be fatal and is due to the donor's immune cells recognising the host cells as foreign. The clinical entity characterised by anorexia, diarrhoea, loss of hair, leukopenia, thrombocytopenia, growth retardation, and eventual death brought about by the graft-versus-host reaction. It can occur in either chronic or acute forms and is treatable by immunosuppressive drugs. Seen most commonly following bone marrow transplantation, acute disease is seen after 5-40 days and chronic disease weeks to months after transplantation, affecting, principally, the gastrointestinal tract, liver, and skin. Radiological appearances of the gastrointestinal tract include; thickened wall, mucosal folds thickened or effaced, increased secretions most likely to be rapid transit of GI tract, mass most likely to be focal oedema, fibrosis, hallmark: diffuse, uniform thickening of small bowel. Synonym: GVH disease. Acronym: GVHD (20 Sep 2002) |