| follicular c. |
inflammation of the gallbladder in which there is conspicuous formation of lymphoid follicles, which commonly contain germinal centers.
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| follicular c. of thyroid gland |
a type of thyroid gland carcinoma with many follicles, although it may have areas without follicles; it is more common in women and is more malignant than papillary carcinoma of thyroid gland. Called also follicular thyroid carcinoma.
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| follicular center c. |
any of a series of B lymphocytes occurring normally in the germinal center and pathologically in the neoplastic nodules of follicular center cell lymphoma; they are regarded as intermediate stages in the development of lymphoblasts and plasma cells from activated lymphocytes and are distinguished according to size (large vs. small) and presence or absence of folds or clefts on the nucleus (cleaved or uncleaved). Follicular center cells are thought to be the B memory cells.
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| follicular center c., large cleaved |
a follicular center cell considered to be intermediate between the small cleaved and small noncleaved stages; it has a diameter of about 12 μm, a nucleus with deep folds or clefts and clumped chromatin, and cytoplasm that is not pyroninophilic but may have immunoglobulin inclusions.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| follicular center c., large noncleaved |
a follicular center cell considered to be the stage immediately preceding the development of the B lymphoblast and migration out of the follicle; it has a diameter of 1520 μm, a nucleus without clefts that contains finely dispersed chromatin, and cytoplasm that is abundant and pyroninophilic.
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