| late apical systolic murmur | A murmur previously considered benign, or even extracardiac, with a possible relationship to pericardial disease; it often represents mitral insufficiency, often localised and of moderate severity but with propensity for developing bacterial endocarditis, and is frequently associated with systolic click and mitral prolapse (Barlow syndrome; a balloon or billowing mitral valve leaflet) often producing a click, murmur, or both, as it prolapses during systole into the left atrium. (05 Mar 2000) |
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| late diastolic murmur | A murmur heard at the end of ventricular diastole (during atrial systole if in sinus rhythm), usually due to obstruction at one of the atrioventricular orifices. Synonym: atriosystolic murmur, late diastolic murmur. (05 Mar 2000) |
| Frantzel's murmur | A murmur of mitral stenosis when louder at its beginning and end than in its midportion. (05 Mar 2000) |
| friction murmur | The sound, heard on auscultation, made by the rubbing of two opposed serous surfaces roughened by an inflammatory exudate, or, if chronic, by nonadhesive fibrosis. Synonym: friction murmur, friction rub. (05 Mar 2000) |
| functional murmur | A cardiac murmur not associated with a significant heart lesion. Synonym: innocent murmur, inorganic murmur. (05 Mar 2000) |