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contrast n. kidney damage by a contrast medium. usually seen in patients already weakened by some other condition such as diabetes mellitus, proteinuria, hypovolemia, multiple myeloma, or pre-existing renal insufficiency; there is usually a sharp decline in the glomerular filtration rate after administration of the agent, sometimes with acute renal failure, followed in a few days by return to the patient's previous level of function. Called also contrast agent or contrast medium nephrotoxicity.
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contrast s. a solution of a substance opaque to the x-ray, used to facilitate radiographic visualization of some organ or structure in the body.
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contrastimulant 1. counteracting or opposing stimulation.  2. a depressant medicine.
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contrastimulism the systematic use of contrastimulant medicines or appliances.
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contrastimulus a remedy, force, or agent that opposes stimulation.
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