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MeSH(Medical Subject Headings) ¸ÂÃã °Ë»ö (http://www.nlm.nih.gov) °á°ú : 5 ÆäÀÌÁö: 6
  • Complement C3-C5 Convertases, Classical Pathway - »õâ Important enzymes in the CLASSICAL COMPLEMENT ACTIVATION PATHWAY. They cleave COMPLEMENT C3 and COMPLEMENT C5.
    Synonyms : Classical Pathway C3-C5 Convertases, Classical Pathway C3 C5 Convertases, Complement C3 C5 Convertases, Classical Pathway
  • Complement C3a - »õâ The smaller fragment generated from the cleavage of complement C3 by C3 CONVERTASE. C3a, a 77-amino acid peptide, is a mediator of local inflammatory process. It induces smooth MUSCLE CONTRACTION, and HISTAMINE RELEASE from MAST CELLS and LEUKOCYTES. C3a is considered an anaphylatoxin along with COMPLEMENT C4A; COMPLEMENT C5A; and COMPLEMENT C5A, DES-ARGININE.
    Synonyms : C3a Complement, Complement 3a, Complement Component 3a, C3a, Complement, Complement, C3a, Component 3a, Complement
  • Complement C3b - »õâ The larger fragment generated from the cleavage of COMPLEMENT C3 by C3 CONVERTASE. It is a constituent of the ALTERNATIVE PATHWAY C3 CONVERTASE (C3bBb), and COMPLEMENT C5 CONVERTASES in both the classical (C4b2a3b) and the alternative (C3bBb3b) pathway. C3b participates in IMMUNE ADHERENCE REACTION and enhances PHAGOCYTOSIS. It can be inactivated (iC3b) or cleaved by various proteases to yield fragments such as COMPLEMENT C3C; COMPLEMENT C3D; C3e; C3f; and C3g.
    Synonyms : C3b Complement, C3bi, Complement 3b, Complement Component 3b, Inactivated C3b, iC3b, C3b, Complement, C3b, Inactivated, Complement, C3b, Component 3b, Complement
  • Complement C3b Inactivator Proteins - »õâ Endogenous proteins that inhibit or inactivate COMPLEMENT C3B. They include COMPLEMENT FACTOR H and COMPLEMENT FACTOR I (C3b/C4b inactivator). They cleave or promote the cleavage of C3b into inactive fragments, and thus are important in the down-regulation of COMPLEMENT ACTIVATION and its cytolytic sequence.
    Synonyms : C3b Inactivators, C3b Inhibitors, Complement 3b Inactivators, Complement 3b Inhibitors, Complement C3b Inactivators, Complement C3b Inhibitor Proteins, Conglutinogen Activating Factors, Factors, Conglutinogen Activating, Inactivators, C3b, Inhibitors, C3b
  • Complement C3c - »õâ A 206-amino-acid fragment in the alpha chain (672-1663) of C3b. It is generated when C3b is inactivated (iC3b) and its alpha chain is cleaved by COMPLEMENT FACTOR I into C3c (749-954), and C3dg (955-1303) in the presence COMPLEMENT FACTOR H.
    Synonyms : C3c Complement, Complement 3c, Complement C3c Fragment, Complement Component 3c, C3c Fragment, Complement, C3c, Complement, Complement, C3c, Component 3c, Complement, Fragment, Complement C3c
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MeSH(Medical Subject Headings) À¯»ç °Ë»ö (http://www.nlm.nih.gov) °á°ú : 0 ÆäÀÌÁö: 6
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