| complement 3c | <chemical> An inactivated form of complement 3b (c3b). Complement 3b is inactivated with the help of two regulatory factors, complement factor h and complement factor I. Complement factor h (c3b inactivator accelerator) makes c3b susceptible to the serine protease, complement factor I (formerly called kaf, c3binf, or enzyme 3b inactivator), to form ic3b. Then complement factor I and a trypsin-like proteolytic enzyme further cleave ic3b into c3c and c3dg. Chemical name: Complement C3c (12 Dec 1998) |
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| complement 3d | <chemical> An inactivated fragment of complement 3b (c3b). Factor h makes c3b susceptible to factor I (formerly called kaf, c3binf, or enzyme 3b inactivator) to form ic3b. Then factor I and a trypsin-like proteolytic enzyme further cleave ic3b into c3c and c3dg. Serum proteases degrade c3dg into complement 3d (c3d) and c3g. Chemical name: Complement C3d (12 Dec 1998) |
| complement 4 | The second component to react in the complement sequence. It is a beta-globulin with a sedimentation coefficient of 18.7, a molecular weight of 240,000 and a serum concentration of 430 micrograms/ml. It is activated by complement 1 and serves as a receptor for c2. (12 Dec 1998) |
| complement 4a | <chemical> Smaller fragment formed when c1s splits c4 into c4a and c4b. As an anaphylatoxin, c4a causes symptoms of immediate hypersensitivity but it has weaker activity than c3a or c5a. Chemical name: Complement C4a (12 Dec 1998) |
| complement 4b | <chemical> Larger fragment formed when c1s splits c4 into c4a and c4b. C4b combines with c2b to form the activated c4b2b complex which is often called the classical pathway c3 convertase. Chemical name: Complement C4b (12 Dec 1998) |
| complement 5 | The fifth component in the complement reaction sequence, probably exists in a complex with c6 and c7. It is a beta-globulin with a sedimentation coefficient of 10, serum concentration of 75 micrograms/ml and molecular weight of 180,000. It is activated by c423 and releases fragments with anaphylatoxic, chemotactic, and histamine-releasing actions and affecting smooth muscle. (12 Dec 1998) |
| complement 5a | <chemical> Smaller fragment formed when c5 convertase splits c5 into c5a and c5b. C5a is a 74-amino acid peptide that includes a carboxy-terminal arginine crucial for its spasmogenic activity and a carbohydrate moiety. C5a is the most potent anaphylatoxin mediating immediate hypersensitivity. Chemical name: Complement C5a (12 Dec 1998) |
| complement 5a, des-arginine | Complement 5a with the carboxy-terminal arginine removed. The arginine is rapidly cleaved from the c5a fragment during complement activation by carboxypeptidase b present in normal human serum. C5a des-arg shows complete loss of spasmogenic activity though it retains some chemotactic ability. (12 Dec 1998) |
| complement 6 | The sixth component in the complement reaction sequence. It is a beta-globulin with a sedimentation coefficient of 8.7 and a molecular weight of 120,000 at 60 micrograms/ml in serum. It may exist in a complex with c5 and c7 and is activated by the binding of c5. (12 Dec 1998) |
| complement 7 | The seventh component in the complement reaction sequence. It is a beta-globulin probably in a complex with c5 and c6 and is activated by c5. The attachment of c7 renders the cell susceptible to lysis. (12 Dec 1998) |
| complement 8 | The next to the last essential component for cell lysis in the complement reaction sequence. It is a gamma-globulin with a molecular weight of 150,000 and a sedimentation coefficient of 8. It is present in trace amounts in serum and can be inhibited, like complement 1, by cation chelators. (12 Dec 1998) |
| complement 9 | The last component in the complement reaction sequence. It is an alpha-globulin present in serum as a trace, with a molecular weight of 80,000 and a sedimentation coefficient of 4.5. For cell lysis, it can be replaced by a metal chelator. (12 Dec 1998) |
| complement activating enzymes | <enzyme> Enzymes present in the complement system which activate one or more components in the system. Registry number: EC 3.- (12 Dec 1998) |
| complement activation | The sequential activation of serum components c1 through c9, initiated by an erythrocyte-antibody complex or by microbial polysaccharides and properdin, and producing an inflammatory response. (12 Dec 1998) |
| complement binding assay | A test for the detection of immune complexes. (05 Mar 2000) |
Synonyms : Classical Pathway C3-C5 Convertases, Classical Pathway C3 C5 Convertases, Complement C3 C5 Convertases, Classical Pathway
Synonyms : C3a Complement, Complement 3a, Complement Component 3a, C3a, Complement, Complement, C3a, Component 3a, Complement
Synonyms : C3b Complement, C3bi, Complement 3b, Complement Component 3b, Inactivated C3b, iC3b, C3b, Complement, C3b, Inactivated, Complement, C3b, Component 3b, Complement
Synonyms : C3b Inactivators, C3b Inhibitors, Complement 3b Inactivators, Complement 3b Inhibitors, Complement C3b Inactivators, Complement C3b Inhibitor Proteins, Conglutinogen Activating Factors, Factors, Conglutinogen Activating, Inactivators, C3b, Inhibitors, C3b
Synonyms : C3c Complement, Complement 3c, Complement C3c Fragment, Complement Component 3c, C3c Fragment, Complement, C3c, Complement, Complement, C3c, Component 3c, Complement, Fragment, Complement C3c
| Comp. |
comprehensive examination: an intensive examination testing a student's proficiency in some special field of knowledge; "she took her comps in English literature"
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| comparative psychology |
the branch of psychology concerned with the behavior of animals
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| compartment |
a small space or subdivision for storage a partitioned section or separate room within a larger enclosed area
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| computerized axial tomography |
computerized tomography: a method of examining body organs by scanning them with X rays and using a computer to construct a series of cross-sectional scans along a single axis
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| computer science |
the branch of engineering science that studies (with the aid of computers) computable processes and structures
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| comp | study of literary works from different cultures (often in translation) |
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| comp | (law) negligence allocated between the plaintiff and the defendant with a corresponding reduction in damages paid to the plaintiff |
| comp | the branch of psychology concerned with the behavior of animals |
| comp | in a relative manner |
| comp | qualities that are comparable |
| comp | examine and note the similarities or differences of |
| comp | consider or describe as similar, equal, or analogous |
| comp | to form the comparative or superlative form on an adjective or adverb |
| comp | be comparable |
| comp | examining resemblances or differences |
| comp | examining resemblances or differences |
| comp | qualities that are comparable |