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phosphatidylinositol synthase <enzyme> An enzyme that catalyses the reaction of CDP-diacylglycerol with inositol to form CMP and phosphatidylinositol; found in the endoplasmic reticulum.
(20 Sep 2002)
citrate (si)-synthase <enzyme> An enzyme of the lyase class that catalyses the condensation of oxaloacetate and the acetyl group of coenzyme a to form citrate and coenzyme a. This is the initial reaction in the tricarboxylic acid cycle.
Chemical name: Citrate oxaloacetate-lyase ((pro-3S)-CH2COO(-)--acetyl-CoA)
Registry number: EC 4.1.3.7
(12 Dec 1998)
citrate synthase Citrate (si)-synthase;an enzyme catalyzing the condensation of oxaloacetate, water, and acetyl-CoA, forming citrate and coenzyme A; an important step in the tricarboxylic acid cycle.
Synonym: citrogenase, condensing enzyme, oxaloacetate transacetase.
(05 Mar 2000)
phosphoribosylanthranilate isomerase-indoleglycerol-phosphate synthase <chemical> EC 5.3.1.24 plus EC 4.1.1.48
Synonym: pai-igps, indoleglycerol phosphate synthase-phosphoribosyl anthranilate isomerase, prai-igps
(26 Jun 1999)
clavaminate synthase <enzyme> From streptomyces clavuligerus; convers proclavaminic acid to clavaminic acid in a reaction requiring fe(2+), alpha-ketoglutarate, and oxygen
Registry number: EC 1.14.11.-
Synonym: clavaminic acid synthase
(26 Jun 1999)
cobalamin (5'-phosphate)synthase <enzyme> From pseudomonas denitrificans; catalyses the synthesis of cobalamin 5'-phosphate from GDP-cobinamide and alpha-ribazole 5'-phosphate, but also the synthesis of cobalamin from GDP-cobinamide and alpha-ribazole
Registry number: EC 2.6.99.-
Synonym: cobv gene product
(26 Jun 1999)
phytochromobilin synthase <enzyme> From plants; reduces biliverdin ixa to phytochromobilin; requires ATP and NADPH
Registry number: EC 1.3.1.-
(26 Jun 1999)
phytoene synthase <enzyme> Calatyzes the 2-step reaction from geranylgeranyl pyrophosphate to phytoene via prephytoene pyrophophate
Registry number: EC 2.5.1.-
Synonym: pys gene product, crtb protein, crtb gene product
(26 Jun 1999)
polyketide synthase <chemical> A group of enzymes functionally and structurally resembling the fatty acid synthase complex of microorganisms which produce the benzoisochromane quinone moiety of granaticin and other antibiotic; genbank y10438 (fkba)
Chemical name: synthetase, polyketide
Synonym: 6-deoxyerythronolide b synthase, 6-deoxyerythronolide-b synthase, debs, type II polyketide beta-ketoacyl synthase, griseusin polyketide synthase, type I polyketide synthase, sterigmatocystin polyketide synthase, st polyketide synthase, urdamycin polyketide synthase, polyketide synthase l1, pksl1 gene product, fkba gene product, niddamycin polyketide synthase, pks enzyme
(26 Jun 1999)
polyketide synthase ketoreductase <enzyme> A component of the polyketide synthase; mapped by analogy with fatty acid synthetase complex.
Registry number: EC 1.1.-
Synonym: pks ketoreductase, actiii gene product
(26 Jun 1999)
myo-inositol-1-phosphate synthase <enzyme> An enzyme that catalyses the formation of myo-inositol-1-phosphate from glucose-6-phosphate in the presence of NAD.
Chemical name: 1L-myo-Inositol-1-phosphate lyase (isomerizing)
Registry number: EC 5.5.1.4
(12 Dec 1998)
myrcene synthase <enzyme> Isolated from the grand fir abies grandis.
Registry number: EC 5.5.-
(26 Jun 1999)
porphobilinogen synthase <enzyme> An enzyme that catalyses the formation of porphobilinogen from two molecules of 5-aminolevulinic acid.
Chemical name: 5-Aminolevulinate hydro-lyase (adding 5-aminolevulinate and cyclizing)
Registry number: EC 4.2.1.24
(12 Dec 1998)
porphobilinogen synthase porphyria An inherited disorder in which there is a deficiency of porphobilinogen synthase; d-aminolevulinate levels are elevated, leading to neurological disturbances.
Synonym: porphobilinogen synthase porphyria.
(05 Mar 2000)
precorrin-3 synthase <enzyme> One of enzymes involved in hydrogenobyrinic acid synthesis; methylates c-20 of precorrin-2 to form precorrin-3; 10 aa amino-terminal sequence given in first source
Registry number: EC 2.1.1.-
Synonym: cbil gene product, precorrin-2 20-methyltransferase
(26 Jun 1999)
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