| uroporphyrinogen-III synthase | <enzyme> An enzyme that catalyses the cyclization of hydroxymethylbilane to yield uroporphyrinogen III and water. Chemical name: Hydroxymethylbilane hydro-lyase (cyclizing) Registry number: EC 4.2.1.75 (12 Dec 1998) |
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| forms of DNA i, II and III | Refers to circular DNA removed from viruses and as plasmids. Form I is the DNA in its normal, supercoiled form. Form II is the DNA after one of the two strands has been nicked (cut apart), and is circular. Form III is the DNA after both strands have been broken, and is linear. (09 Oct 1997) |
| Le Fort III craniofacial dysjunction | A complex fracture in which the facial bones are separated from the cranial bones. Synonym: Le Fort III craniofacial dysjunction, Le Fort III fracture, transverse facial fracture. (05 Mar 2000) |
| Le Fort III fracture | A complex fracture in which the facial bones are separated from the cranial bones. Synonym: Le Fort III craniofacial dysjunction, Le Fort III fracture, transverse facial fracture. (05 Mar 2000) |
| ABO antigens | <haematology, immunology> A system of genetically determined antigens (proteins) located on the surface of the erythrocyte. The presence of these specific antigens gives a blood its unique properties. Because of the antigen differences existing between individuals, blood groups are significant in blood transfusions, maternal-foetal incompatibilities (erythroblastosis foetalis), tissue and organ transplantation. (27 Sep 1997) |
| Am antigens | Allotypic determinants (antigens) on human immunoglobulin alpha heavy chains. (05 Mar 2000) |
| antigens | Substances which are capable, under appropriate conditions, of inducing a specific immune response and of reacting with the products of that response, that is, with specific antibodies or specifically sensitised T-lymphocytes, or both. Antigens may be soluble substances, such as toxins and foreign proteins, or particulates, such as bacteria and tissue cells; however, only the portion of the protein or polysaccharide molecule known as the antigenic determinant (epitopes) combines with antibody or a specific receptor on a lymphocyte. (12 Dec 1998) |
| antigens, archaeal | Substances of archaeal origin that have antigenic activity. (12 Dec 1998) |
| antigens, bacterial | Substances elaborated by bacteria that have antigenic activity. (12 Dec 1998) |
| antigens, CD | <immunology> Differentiation antigens residing on human leukocytes. CD stands for cluster of differentiation, which refers to groups of monoclonal antibodies that show similiar reactivity with certain subpopulations of antigens. The subpopulations of antigens are also known by the same CD designation. (12 Dec 1998) |
| antigens, CD1 | <immunology> Glycoproteins expressed on cortical thymocytes and on some dendritic cells and B-cells. Their structure is similar to that of MHC class I and their function has been postulated as similar also. Cd1 antigens are highly specific markers for human langerhans cells. (12 Dec 1998) |
| antigens, CD11 | <immunology> A group of three different alpha chains (CD11a, CD11b, CD11c) that are associated with an invariant CD18 beta chain (antigens, CD18). The three resulting leukocyte-adhesion molecules (receptors, leukocyte adhesion) are lymphocyte function-associated antigen-1, macrophage-1 antigen, and antigen, p150,95. (12 Dec 1998) |
| antigens, CD13 | <enzyme, immunology> Glycoproteins expressed on human granulocyte-monocyte progenitor colony forming units (cfu-gm) and their more differentiated progeny. The enzymes are also found in a large number of tissues, often associated with membranes. Registry number: EC 3.4.11.2 (12 Dec 1998) |
| antigens, CD14 | <immunology> Glycolipid-anchored membrane glycoproteins expressed on cells of the myelomonocyte lineage including monocytes, macrophages, and some granulocytes. They function as receptors for the complex of lipopolysaccharide (lps) and lps-binding protein. (12 Dec 1998) |
| antigens, CD15 | <immunology> Carbohydrate antigen which is accumulated in various human cancer tissues and secreted into the blood stream. The carbohydrate moiety can be further modified with fucose or sialic acid. Monoclonal antibodies have been determined which can discriminate each subgroup of this antigen in the sera of cancer patients. Sialyl ssea-1 antigen is particularly elevated in the sera of patients with a variety of tumours. (12 Dec 1998) |