| antigens, polyomavirus transforming | Polyomavirus antigens which cause infection and cellular transformation. The large t antigen is necessary for the initiation of viral DNA synthesis, repression of transcription of the early region and is responsible in conjunction with the middle t antigen for the transformation of primary cells. Small t antigen is necessary for the completion of the productive infection cycle. (12 Dec 1998) |
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| antigens, protozoan | Any part or derivative of any protozoan that elicits immunity; malaria (plasmodium) and trypanosome antigens are presently the most frequently encountered. (12 Dec 1998) |
| antigens, surface | Antigens on surfaces of cells, including infectious or foreign cells or viruses. They are usually protein-containing groups on cell membranes or walls and may be isolated. (12 Dec 1998) |
| antigens, thy-1 | A group of differentiation surface antigens, among the first to be discovered on thymocytes and T-lymphocytes. Originally identified in the mouse, they are also found in other species including humans, and are expressed on brain neurons and other cells. (12 Dec 1998) |
| antigens, t-independent | Antigens which may directly stimulate b lymphocytes without the cooperation of t lymphocytes. (12 Dec 1998) |
| antigens, tumour-associated, carbohydrate | Carbohydrate antigens expressed by malignant tissue. They are useful as tumour markers and are measured in the serum by means of a radioimmunoassay employing monoclonal antibodies. (12 Dec 1998) |
| antigens, viral | Substances elaborated by viruses that have antigenic activity. (12 Dec 1998) |
| antigens, viral, tumour | Those proteins recognised by antibodies from serum of animals bearing tumours induced by viruses; these proteins are presumably coded for by the nucleic acids of the same viruses that caused the neoplastic transformation. (12 Dec 1998) |
| CDE antigens | rh blood group |
| CENP antigens | <molecular biology> Proteins of the kinetochore (CENP A 27 kD, CENP B 80 kD, CENP C 140 kD and CENP D 50 kD) that react strongly with antibodies from CREST sera. (18 Nov 1997) |
| Gm antigens | Allotypic determinants (antigens) that are present on the heavy chain of immunoglobulin G. There are 25 different determinants present throughout the human population. (05 Mar 2000) |
| Rh antigens | rh blood group |
| group antigens | Antigen's that are shared by related genera of microorganisms. (05 Mar 2000) |
| minor histocompatibility antigens | Allelic alloantigens often responsible for weak graft rejection in cases when (major) histocompatibility has been established by standard tests. In the mouse they are coded by more than 500 genes at up to 30 minor histocompatibility loci. The most well-known minor histocompatibility antigen in mammals is the h-y antigen. (12 Dec 1998) |
| minor lymphocyte stimulatory antigens | Endogenous superantigens responsible for inducing strong proliferative responses in T-cells in mixed lymphocyte reactions (see mixed lymphocyte culture test). They are encoded by mouse mammary tumour viruses that have integrated into the germ line as DNA proviruses (minor lymphocyte stimulatory loci). (12 Dec 1998) |
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