| Flint's murmur | A diastolic murmur, similar to that of mitral stenosis, heard best at the cardiac apex in some cases of free aortic insufficiency; it is thought to be caused by the turbulent regurgitating stream from the aorta mixing into the stream simultaneously entering from the left atrium through the mitral valve, causing posterior movement of the anterior leaflet of the mitral valve with transient acceleration of blood flow through the mitral valve. Synonym: Austin Flint murmur. (05 Mar 2000) |
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| late apical systolic murmur | A murmur previously considered benign, or even extracardiac, with a possible relationship to pericardial disease; it often represents mitral insufficiency, often localised and of moderate severity but with propensity for developing bacterial endocarditis, and is frequently associated with systolic click and mitral prolapse (Barlow syndrome; a balloon or billowing mitral valve leaflet) often producing a click, murmur, or both, as it prolapses during systole into the left atrium. (05 Mar 2000) |
| late diastolic murmur | A murmur heard at the end of ventricular diastole (during atrial systole if in sinus rhythm), usually due to obstruction at one of the atrioventricular orifices. Synonym: atriosystolic murmur, late diastolic murmur. (05 Mar 2000) |
| Frantzel's murmur | A murmur of mitral stenosis when louder at its beginning and end than in its midportion. (05 Mar 2000) |
| friction murmur | The sound, heard on auscultation, made by the rubbing of two opposed serous surfaces roughened by an inflammatory exudate, or, if chronic, by nonadhesive fibrosis. Synonym: friction murmur, friction rub. (05 Mar 2000) |
| functional murmur | A cardiac murmur not associated with a significant heart lesion. Synonym: innocent murmur, inorganic murmur. (05 Mar 2000) |
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