| steroid secretory rate | The rate of glandular secretion of a given steroid, usually expressed as milligrams per day; does not include any amount of the steroid that might be formed extraglandularly. (05 Mar 2000) |
|---|---|
| steroid sulfatase deficiency | A form of ichthyosis, due to 3-beta-hydroxysteroidsulfate sulfatase deficiency, that appears at birth or in early infancy and affects males; characterised by scaling predominantly on the neck and trunk but not on the palms and soles; histologically, there is hyperkeratosis, a granular layer in the epidermis, and normal epidermal cell turnover. Synonym: steroid sulfatase deficiency. (05 Mar 2000) |
| steroid sulfotransferase | <enzyme> Catalyses the reaction of 3'-phosphoadenylyl sulfate and a phenolic steroid to form adenosine 3',5'-bisphosphate and steroid o-sulfate; has broad specificity Registry number: EC 2.8.2.15 Synonym: phenolic steroid sulfotransferase (26 Jun 1999) |
| steroid ulcer | An ulcer, usually on the leg or foot, developing from a wound in patients undergoing long-term steroid therapy; results from the wound-healing inhibitory effects characteristic of steroids. (05 Mar 2000) |
| steroid withdrawal syndrome | <syndrome> A condition exhibited by persons who previously had been receiving large therapeutic doses of glucocorticoid hormones for long periods of time; pituitary-adrenocortical insufficiency is manifested, particularly during stress, for as long as a year or more thereafter and varying degrees of emotional disturbance may be exhibited. (05 Mar 2000) |
| 17-ketogenic steroid assay test | A colourimetric test, based on the Zimmermann reaction, which indicates metabolites or adrenal and testicular steroids excreted as 17-ketones in the urine; increased values are most striking in adrenocortical tumours, decreased values in Addison's disease or in panhypopituitarism. Synonym: ketogenic corticoids test. (05 Mar 2000) |
| 3 beta-hydroxy-delta 5-C(27)-steroid dehydrogenase | <enzyme> Second enzyme in the sequence that converts cholesterol to bile acids; deficiency leads to chronic liver disease in childhood Registry number: EC 1.1.1.- Synonym: 7 alpha-hydroxycholesterol 3 beta-dehydrogenase, 7-hydroxycholesterol 3-dehydrogenase, 3 beta-hydroxy-delta(5)-c(27)-steroid oxidoreductase, 5-cholestene-3beta,7alpha-diol oxidase (26 Jun 1999) |
| 3-oxo-5 beta-steroid delta 4-dehydrogenase | <enzyme> Do not confuse with EC 1.3.1.23 (cholestenone 5 beta-reductase) which is also steroid 5 beta-reductase in chemline; do not use for enzyme using NADP-see EC 1.3.1.23 and EC 1.3.1.3 Chemical name: 3-oxo-5 beta-steroid delta(4)dehydrogenase Registry number: EC 1.3.99.6 Synonym: steroid 5 beta-reductase, testosterone 5 beta-reductase, 4-ene-5 beta-reductase, delta(4)-3-ketosteroid-5 beta-(acceptor)-reductase, testosterone 5beta-reductase, delta(4)-5beta-reductase, cytosolic 4-ene-reductase (26 Jun 1999) |
| accessory adrenal | An island of cortical tissue separate from the adrenal gland, usually found in the retroperitoneal tissues, kidney, or genital organs. Synonym: adrenal rest. (05 Mar 2000) |
| acute adrenal crisis | <endocrinology> An abrupt life-threatening state which is caused by insufficient production of cortisol by the adrenal gland. A typical finding in Addison's disease. Individuals who have been taking corticosteroids (glucocorticoids) for a prolonged period of time (weeks to months) are at risk for acute adrenal crisis if the medication is stopped abruptly. For this reason, corticosteroid medication are withdrawn slowly on a diminishing dosing schedule. Symptoms include low blood pressure (shock), weakness, headache, vomiting, fever chills, tachycardia and sweating. Treatment includes blood pressure support and intravenous hydrocortisone. (27 Sep 1997) |
| adrenal | <anatomy> Suprarenal. Origin: Pref. Ad- + renal. Source: Websters Dictionary (01 Mar 1998) |
| adrenal adenoma | <radiology> Benign adrenal tumour, hyperfunctioning adenoma can cause, primary hyperaldosteronism, Cushing syndrome, nonfunctional adenoma seen in 2-8% of population, differentiate from metastasis, MRI: metastasis bright on T2, biopsy, follow see: adrenal mass (12 Dec 1998) |
| adrenal androgen | Any androgenic hormone of adrenocortical origin; e.g., dehydroepiandrosterone (and its sulfate), androstenedione, 11b-hydroxyandrostenedione. (05 Mar 2000) |
| adrenal androgen-stimulating hormone | A putative pituitary hormone that may be responsible for increased secretion of adrenal androgens at the time of puberty. (05 Mar 2000) |
| adrenal angiography | <radiology> Adrenal arteriography, 3 arteries: superior - inferior phrenic a., middle - aorta, inferior - renal a., difficult to inject all 3; arteriography usually not attempted adrenal venography, venous sampling, may define anatomy, may rupture capsule and ablate function (12 Dec 1998) |