| human serum | See: dried human serum, normal human serum. (05 Mar 2000) |
|---|---|
| human serum jaundice | An obsolete name for hepatitis transmitted parenterally, usually by blood or blood products; usually due to hepatitis B. (05 Mar 2000) |
| serum | <haematology> The clear portion of any body fluid, the clear fluid moistening serous membranes. 2. Blood serum, the clear liquid that separates from blood on clotting. 3. Immune serum, blood serum from an immunised animal used for passive immunisation, an antiserum, antitoxin or antivenin. (18 Nov 1997) |
| serum accelerator | <chemical> Heat- and storage-stable plasma protein that is activated by tissue thromboplastin to form factor viia in the extrinsic pathway of blood coagulation. The activated form then catalyses the activation of factor x to factor xa. Chemical name: Blood-coagulation factor VII (12 Dec 1998) |
| serum accelerator globulin | A substance in serum that accelerates the conversion of prothrombin to thrombin in the presence of thromboplastin and calcium; produced by the action of traces of thrombin upon plasma accelerator globulin. (05 Mar 2000) |
| serum accident | Anaphylactic shock resulting from injection of foreign serum for therapeutic purposes. See: serum sickness. (05 Mar 2000) |
| serum agar | An enriched medium for cultivation of fastidious organisms; prepared by adding sterile serum to melted agar. (05 Mar 2000) |
| serum agglutinin | An antibody which coats erythrocytes; the cells do not agglutinate when suspended in saline, but do agglutinate when suspended in serum or other protein media such as albumin. Synonym: incomplete antibody. (05 Mar 2000) |
| serum albumin | <protein> The serum level of the low molecular protein albumin. Albumin, produced by the liver, plays an important role in maintaining plasma oncotic pressure. Normal serum albumin should be 3.5-5.0 grams per decilitre. Low serum albumin can be found in cases of liver disease and malnutrition. (27 Sep 1997) |
| serum albumin, bovine | Serum albumin from cows, commonly used in in vitro biological studies. (12 Dec 1998) |
| serum albumin, radio-iodinated | <chemical> Normal human serum albumin mildly iodinated with radioactive iodine (131-I) which has a half-life of 8 days, and emits beta and gamma rays. It is used as a diagnostic aid in blood volume determination. Pharmacological action: radiopharmaceuticals. (12 Dec 1998) |
| serum amyloid | In secondary amyloidosis the fibrils deposited in tissues are unrelated to immunoglobulin light chains (in contrast to the situation in primary amyloidosis) and are made of amyloid A protein (AA protein). This is derived from serum amyloid A (SAA) that is the apolipoprotein of a high density lipoprotein and an acute phase protein. Partial proteolysis converts SAA into the pleated sheet configuration of the amyloid fibrils. Amyloid P protein is also found as a minor component of the fibrils (in both primary and secondary amyloidosis) and is derived from serum amyloid P that has similarity to C-reactive protein. The physiological role remains obscure. (18 Nov 1997) |
| serum amyloid P component | Precursor of amyloid component P, found in basement membrane. Member of the pentraxin family. See: serum amyloid. (18 Nov 1997) |
| serum bactericidal test | Method of measuring the bactericidal activity contained in a patient's serum as a result of antimicrobial therapy. It is used to monitor the therapy in bacterial endocarditis, osteomyelitis and other serious bacterial infections. As commonly performed, the test is a variation of the broth dilution test. (12 Dec 1998) |
| serum bicarbonate | A measure of the bicarbonate level in the blood based on a venipuncture specimen. The serum carbon dioxide is one of the normally reported values in the electrolytes profile. Lower levels of carbon dioxide indicate an acidosis. The normal level is 20 to 29 mEq/L. Lower than normal levels can indicate diabetic ketoacidosis, lactic acidosis, alcoholic ketoacidosis, kidney disease, renal failure, diarrhoea, Addison's disease, ethylene glycol poisoning or methanol poisoning. Greater than normal levels can be seen with excessive vomiting, hyperaldosteronism and Cushing's syndrome. (27 Sep 1997) |