| testis | <anatomy> One of the two male reproductive glands located in the cavity of the scrotum. The testes produce sperm and male sex hormones. (13 Nov 1997) |
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| testis cords | The germinal cord's of the embryonic testis. (05 Mar 2000) |
| testis ectopia | Testis that is malpositioned other than along the normal path of descent. Synonym: ectopia testis, parorchidium. (05 Mar 2000) |
| testis-determining factor | The product of a gene on the short arm of the Y chromosome that is responsible for production of testes. (05 Mar 2000) |
| testitis | <pathology> Inflammation of a testis. The disease is marked by pain, swelling and a feeling of weight. It may occur idiopathically or it may be associated with conditions such as mumps, gonorrhoea, filarial disease, syphilis or tuberculosis. (18 Nov 1997) |
| testoid | Synonym: androgenic, androgen. Origin: testis + G. Eidos, resemblance (05 Mar 2000) |
| testoid hyperthecosis | Hyperplasia of Leydig cells of the testis. (05 Mar 2000) |
| testolactone | <chemical> A synthetic antineoplastic agent produced by microbial transformation of progesterone, testosterone, or other steroidal substaces. It is used as adjunctive therapy in the palliative treatment of advanced or disseminated breast cancer in postmenopausal women. Pharmacological action: antineoplastic agent, hormonal. Chemical name: D-Homo-17a-oxaandrosta-1,4-diene-3,17-dione (12 Dec 1998) |
| testosterone | <hormone> Male sex hormone (androgen) secreted by the interstitial cells of the testis of mammals and responsible for triggering the development of sperm and of many secondary sexual characteristics. (18 Nov 1997) |
| testosterone 15-alpha hydroxylase | <enzyme> A haem-thiolate protein (cytochrome p-450) Registry number: EC 1.14.15.- Synonym: cytochrome p-450(15alpha), testosterone 15-alpha monooxygenase, steroid 15-alpha-hydroxylase, cytochrome p-4502a-4, cyp2a-4, cyp2a4 (26 Jun 1999) |
| testosterone 16 beta-hydroxylase | <enzyme> See also record for testosterone hydroxylase Registry number: EC 1.14.99.- Synonym: ttt 16 beta-hydroxylase (26 Jun 1999) |
| testosterone 17 beta-dehydrogenase | <enzyme> Catalyses reversibly the oxidation of testosterone to 4-androstene-3,17-dione in the presence of nad; was mapped to testosterone dehydrogenases (81-93) (see under 17-hydroxysteroid dehydrogenases (81-90); on-line search 17-hydroxysteroid dehydrogenases (81-93), index medicus see testosterone dehydrogenases (91-93) and 17-hydroxysteroid dehydrogenases (81-90) Registry number: EC 1.1.1.63 Synonym: 17 beta-hydroxysteroid-nad+ 17-oxidoreductase (26 Jun 1999) |
| testosterone 2alpha-hydroxylase | <enzyme> From mouse liver, member of the murine cytochrome p450 2d family; amino-terminal amino acid sequence given in first source Registry number: EC 1.14.99.- Synonym: cytochrome p450 2alpha, cytochrome p-450 2alpha, androstenedione 2alpha-hydroxylase, androgen 2alpha-hydroxylase (26 Jun 1999) |
| testosterone 5-alpha-reductase | <enzyme> Chemical name: 3-Oxo-5 alpha-steroid:(acceptor) delta(4)-oxidoreductase Registry number: EC 1.3.99.5 (12 Dec 1998) |
| testosterone 6-beta hydroxylase | <enzyme> Pcn2 is an allelic variant form (2 amino acid alterations); for cyp3a2, consider also lidocaine n-deethylase Registry number: EC 1.14.13.- Synonym: cytochrome p450(6 beta), cytochrome p-450 6b-1(pb1), cyp6b1, testosterone 6beta-hydroxylase, cyt p450 6beta-3, cytochrome p450(pcn2), 6beta-a gene product, cyp3a2, cyp6b3 (26 Jun 1999) |