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succinyl an acyl radical of succinic acid.
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succinyl CoA succinyl coenzyme A.
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succinyl CoA synthetase succinate-CoA ligase (GDP-forming).
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succinyl coenzyme A the succinate monothioester of coenzyme A, a high energy intermediate formed in the tricarboxylic acid cycle (q.v.). It is also a precursor in the synthesis of porphyrins.
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succinylacetoacetate a compound formed by reduction of fumarylacetoacetate; it occurs at elevated levels in tyrosinemia, type I, due to the deficiency of fumarylacetoacetase. It is readily decarboxylated to succinylacetone (q.v.); both compounds can cause hepatorenal damage.
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