| micromyeloblastic leukaemia | A form of myelocytic leukaemia in which relatively large proportions of micromyeloblasts are found in the circulating blood and in bone marrow and other tissues. (05 Mar 2000) |
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| mixed cell leukaemia | Term infrequently used as a designation for granulocytic leukaemia, thereby emphasizing the occurrence of different types of cells in the myeloid series (i.e., neutrophilic, eosinophilic, and basophilic granulocytes), in contrast to the comparatively monotonous pattern observed in lymphocytic and monocytic leukaemia. (05 Mar 2000) |
| CNS leukaemia | <oncology> Invasion of the brain or spinal cord by leukaemic cells. This may be diagnosed by examination of the surrounding cerebrospinal fluid. Origin: Gr. Haima = blood (13 Nov 1997) |
| moloney leukaemia virus | A murine virus arising during the propagation of s37 mouse sarcoma, and causing lymphoid leukaemia in mice. It also infects rats and newborn hamsters and is apparently transmitted vertically to embryos in utero and through mother's milk. (12 Dec 1998) |
| Moloney murine leukaemia virus | <molecular biology, virology> Replication competent retrovirus (Oncovirinae) that causes leukaemia in mice, isolated by Moloney from cell free extracts made from a transplantable mouse sarcoma. (18 Nov 1997) |
| monocytic leukaemia | Cancer of the blood due to proliferation of cells of the monocyte series. Origin: Gr. Haima = blood (13 Nov 1997) |
| common acute lymphoblastic leukaemia | <haematology, oncology> A sub-type of acute lymphoblastic leukaemia affecting cells early in the B lymphocyte lineage which accounts for about 80% of all acute lymphoblastic leukaemia. Origin: Gr. Haima = blood (13 Nov 1997) |
| mouse leukaemia viruses | Retroviruses of the murine leukaemia-sarcoma complex that produce leukaemia and sometimes lymphosarcomas in mice, including the Abelron, Gross, Moloney, Friend, and Rauscher strains of virus; they have been isolated from inbred mice having high incidence of spontaneous lymphoid leukaemia. (05 Mar 2000) |
| plasma cell leukaemia | An unusual disease characterised by leukocytosis and other signs and symptoms that are suggestive of leukaemia, in association with diffuse infiltrations and aggregates of plasma cells in the spleen, liver, bone marrow, and lymph nodes, and the presence of considerable numbers of plasma cells in the circulating blood; the total number of leukocytes in the latter may range from normal levels to 80,000 or 90,000 per cu mm, and 5 to 90% may be plasma cells; multiple myelomas are observed in some examples of plasma cell leukaemia, but discrete nodules are not formed in bone. Although there are other clinicopathologic differences in the two conditions, they may be phases of the same basic process. (05 Mar 2000) |
| murine leukaemia | A leukaemic disorder of mice caused by a number of different type C retroviruses. (05 Mar 2000) |
| murine leukaemia virus | <virology> A group of type C retroviruses infecting mice and causing in some strains lymphatic leukaemia after a long latent period. Nearly all are replication competemt and v onc minus. See: Abelson leukaemia virus. (18 Nov 1997) |
| myeloblastic leukaemia | A form of granulocytic leukaemia in which there are large numbers of myeloblasts in various tissues (and organs) and in the circulating blood; the immature forms may amount to 30 to 60% (or even a greater proportion) of the increased total number of white blood cells. Used synonymously for acute granulocytic leukaemia. Synonym: leukaemic myelosis. (05 Mar 2000) |
| myelocytic leukaemia | <haematology, tumour> A form of leukaemia characterised by an uncontrolled proliferation of myelopoietic cells in the bone marrow and in extramedullary sites, and the presence of large numbers of immature and mature granulocytic forms in various tissues (and organs) and in the circulating blood. The total count may range from 1000 (aleukaemic variety) to several hundred thousand per cu mm. The predominant cell is usually of the neutrophilic series, but, in a few instances, eosinophilic or basophilic granulocytes, or even megakaryocytes, may represent the chief form; early in granulocytic leukaemia, the circulating blood may contain excessive numbers of all of the granulocytic forms. Synonym: leukaemic myelosis, myelocytic leukaemia, myelogenic leukaemia, myelogenous leukaemia, myeloid leukaemia. (05 Mar 2000) |
| polymorphocytic leukaemia | Granulocytic leukaemia, especially any variety in which the predominant cells are mature, segmented granulocytes. (05 Mar 2000) |
| myelomonocytic leukaemia | A variant of granulocytic leukaemia with monocytosis in the peripheral blood. Synonym: Naegeli type of monocytic leukaemia. (05 Mar 2000) |