| 영문 | Paget's disease | 한글 | 파제트병 |
|---|---|---|---|
| 설명 | 1. 뼈파제트병. 변형성 뼈염. 뼈흡수 후 뼈형성이 반복적으로 과도하게 일어나는 것으로, 새롭게 형성된 뼈는 무질서하고 구조적으로 견고하지 못하다. 뼈흡수의 증가가 반복되고 이어서 과잉보수를 꾀하여 약하고 변형된 뼈의 부피가 증가되는 것을 특징으로 하는 뼈병이다. 궁둥뼈의 만곡, 편평뼈의 변형을 일으키고, 동통 및 병적 골절을 수반한다. 2. 유방파제트병. 젖꽃판 및 젖꼭지의 염증성 암성 질병으로서 보통은 젖샘 및 유방 깊은 곳의 암을 동반한다. 보통 중년부인에게 발생한다. |
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| 영문 | Parkinson disease | 한글 | 파킨슨병 |
|---|---|---|---|
| 설명 | 나이든 사람에게 발생하는 신경계의 퇴행병이다. 주로 운동을 담당하는 중간뇌부위가 침범된다. 원인은 바이러스, 약물, 혹은 동맥경화증 등으로 알려진 경우도 있으나, 원인을 알 수 없는 경우가 많다. 증상은 가면얼굴, 쓰러질 것 같은 걸음걸이, 손떨림, 근육의 강직, 앞으로 기울어진 자세 등임. 치료는 특별한 것이 없으며, 대개 보존적 치료(완치를 목적으로 하지 않고 단지 환자의 생활을 보조해주는 정도의 치료)를 시행한다. 최근, 죽은 태아의 뇌를 이식하는 뇌 이식술에 의한 치료효과가 높다는 보고가 있다. |
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| 영문 | endemic disease | 한글 | 풍토병 |
|---|---|---|---|
| 설명 | 인간사회에 항상 존재하지만 특수한 기후나 토질로 인하여 특정지역에만 존재하는 사망률이 낮고, 임상적으로도 드물게 볼 수 있는 병. 특히 그 토지의 풍토-기후-생물-토양 등의 자연환경과 그 지방 주민의 풍속-습관-인습 등이 복잡하게 얽혀서 생긴 특수한 병을 가리킨다. 일반적으로 그 지방 주민의 사망률은 그다지 높지 않지만 근절되기 어려운 것이 특징이다. 지방병이라는 말은 어느 지방에 한정하여 볼 수 있는 병이라는 점에서는 같지만, 풍토환경과 밀접한 관계가 있다는 데서 보면 풍토병이라는 용어가 적절하다. 국내적으로는 쯔쯔가무시병, 야생토끼병, 렙토스피라증 등이 알려져 있고, 세계적으로는 말라리아, 황열, 페트스, 일본주혈흡충증 등이 알려져 있다. |
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| 영문 | Hodgkin's disease | 한글 | 호지킨병 |
|---|---|---|---|
| 설명 | 악성림프종의 한 형태이다. 호지킨병은 방사선 치료에 대단히 예민해서 충분한 양의 방사선으로 완전한 근치적 치료가 가능하다. |
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| CHD | Chediak-Higashi disease; childhood disease; chronic hemodialysis; congenital or congestive heart dis... |
|---|---|
| PDHA | pyruvate dehydrogenase alpha |
| PDHa | pyruvate dehydrogenase in active form |
| PDHB | pyruvate dehydrogenase beta |
| LD | labor and delivery; laboratory data; labyrinthine defect; lactate dehydrogenase; laser Doppler; lear... |
| glycine cleavage complex | A complex of several proteins that catalyze the reversible reaction of glycine with tetrahydrofolate to produce CO2, NH3, and N5,N10-methylenetetrahydrofolate; a deficiency of this enzyme (or one of its subunits) will result in nonketotic hyperglycinaemia. Synonym: glycine synthase. (05 Mar 2000) |
|---|---|
| Golgi complex | <cell biology> Intracellular stack of membrane bounded vesicles in which glycosylation and packaging of secreted proteins takes place. Part of the GERL complex. Synonym: Golgi body, Golgi vesicles, dictyosome (in plants), parabasal body (in flagellate protozoa). (11 Jan 1998) |
| membrane attack complex | <immunology> A term originally used to refer to the heat labile factor in serum that causes immune cytolysis, the lysis of antibody coated cells and now referring to the entire functionally related system comprising at least 20 distinct serum proteins that is the effector not only of immune cytolysis but also of other biologic functions. Complement activation occurs by two different sequences, the classic and alternative pathways. The proteins of the classic pathway are termed components of complement and are designated by the symbols C1 through C9. C1 is a calcium dependent complex of three distinct proteins C1q, C1r and C1s. The proteins of the alternative pathway (collectively referred to as the properdin system) and complement regulatory proteins are known by semisystematic or trivial names. Fragments resulting from proteolytic cleavage of complement proteins are designated with lower case letter suffixes, for example, C3a. Inactivated fragments may be designated with the suffix i, for example C3bi. Activated components or complexes with biological activity are designated by a bar over the symbol for example C1 or C4b, 2a. The classic pathway is activated by the binding of C1 to classic pathway activators, primarily antigen-antibody complexes containing IgM, IgG1, IgG3, C1q binds to a single IgM molecule or two adjacent IgG molecules. The alternative pathway can be activated by IgA immune complexes and also by nonimmunologic materials including bacterial endotoxins, microbial polysaccharides and cell walls. Activation of the classic pathway triggers an enzymatic cascade involving C1, C4, C2 and C3, activation of the alternative pathway triggers a cascade involving C3 and factors B, D and P. Both result in the cleavage of C5 and the formation of the membrane attack complex. Complement activation also results in the formation of many biologically active complement fragments that act as anaphylatoxins, opsonins or chemotactic factors. (05 Jan 1998) |
| charge transfer complex | A complex between two organic molecules in which an electron from one (the donor) is transferred to the other (the acceptor), becoming generally distributed throughout the latter; subsequent transfer of a hydrogen atom completes the reduction of the acceptor; such complex's are generally highly coloured and may be so observed, a network of hydrogen bridges at the catalytic centre of certain proteases. Synonym: charge transfer system. (05 Mar 2000) |
| periodontitis complex | Vertical resorption of the alveolar process with pockets of uneven depth on adjacent teeth, and with traumatic occlusion as a factor. (05 Mar 2000) |
| ribosome-lamella complex | A cylindrical cytoplasmic inclusion composed of concentrically arranged sheets of membranes alternating with rows of ribosomes; characteristic of the hairy cell in leukaemic reticuloendotheliosis. (05 Mar 2000) |
| persecution complex | A feeling that others have evil designs against one's well-being. (05 Mar 2000) |
| met repressor operator complex | Repressor protein, 104 residues, product of the metJ gene, which regulates methionine biosynthesis in E. Coli. Dimeric molecules bind to adjacent sites 8 base pairs apart on the DNA, sequence recognition is by interaction between antiparallel strands of protein and the major groove of the B form DNA duplex. (18 Nov 1997) |
| Meyenburg's complex | Clusters of small bile ducts occurring in polycystic livers, separate from the portal areas. (05 Mar 2000) |
| Michaelis complex | Binary complex of an enzyme. (05 Mar 2000) |
| monophasic complex | A complex in the electrocardiogram that is entirely negative or entirely positive. (05 Mar 2000) |
| mother superior complex | The tendency of a psychotherapist to play a mothering role to the detriment of the therapeutic process. (05 Mar 2000) |
| complement membrane attack complex | The assembly of complement plasma glycoproteins c5b, c6, c7, c8, and polymeric c9 as a group on biological membranes. The complex forms transmembrane channels which displace lipid molecules and other constituents, thus disrupting the phospholipid bilayer of target cells leading to cell lysis by osmotic leakage. The formation of the membrane attack complex is the terminal step in the complement cascade. (12 Dec 1998) |
| complex | Complicated, not simple. Origin: L. Complexus = woven together, encompassing (18 Nov 1997) |
| complex carbohydrate | <biochemistry> The combination of carbohydrates and fibre. (05 Jan 1998) |