| LAS | laboratory automation system; lateral amyotrophic sclerosis; laxative abuse syndrome; left anterior-... |
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| NCDA | National Council on Drug Abuse |
| NIAAA | National Institute of Alcohol Abuse and Alcoholism |
| NIDA | National Institute of Drug Abuse |
| PDAP | Palmer drug abuse program |
| Stilling's gelatinous substance | The central gray matter of the spinal cord surrounding the central canal. Synonym: substantia intermedia centralis et lateralis, anterior gray column, Stilling's gelatinous substance, substantia gelatinosa centralis. (05 Mar 2000) |
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| neurosecretory substance | The secretion of nerve cell bodies located in the hypothalamus; the substance is transported by way of hypothalamo-hypophysial tract fibres into the neurohypophysis where the terminals of the nerve fibres contain the secretion. As seen in the fibres and terminals with a light microscope, the substance appears as Herring bodies or hyaline bodies of the pituitary (see under body). See: hyaline bodies of pituitary. (05 Mar 2000) |
| Nissl substance | The material consisting of granular endoplasmic reticulum and ribosomes that occurs in nerve cell bodies and dendrites. Synonym: basophil substance, basophilic substance, chromophil substance, Nissl bodies, Nissl granules, substantia basophilia, tigroid bodies, tigroid substance. (05 Mar 2000) |
| substance | The material constituting an organ or body, also called substantia. Origin: L. Substantia (18 Nov 1997) |
| substance dependence | A pattern of behavioural, physiologic, and cognitive symptoms that develop due to substance use or abuse; usually indicated by tolerance to the effects of the substance and withdrawal symptoms that develop when use of the substance is terminated. (05 Mar 2000) |
| substance-induced organic mental disorders | Mental disorders caused by use of drugs, e.g., cocaine. (05 Mar 2000) |
| substance of lens of eye | That which constitutes the lens of the eye, composed of a nucleus and a cortex and covered by an epithelium. Synonym: substantia lentis. (05 Mar 2000) |
| substance P | A vasoactive intestinal peptide (1348 D) found in the brain, spinal ganglia and intestine of vertebrates. Induces vasodilatation, salivation and increases capillary permeability. Sequence: RPKPQFFGLM. (18 Nov 1997) |
| substance-related disorders | These non-psychotic disorders include those related to the taking of a drug of abuse (including alcohol), to the side effects of a medication, and to toxin exposure. (12 Dec 1998) |
| substance withdrawal syndrome | <syndrome> Physiological and psychological symptoms associated with withdrawal from the use of a drug after prolonged administration or habituation. The concept includes withdrawal from smoking or drinking, as well as withdrawal from an administered drug. (12 Dec 1998) |
| innominate substance | The region of the forebrain that lies ventral to the anterior half or so of the lentiform nucleus, extending in the frontal plane from the lateral preopticohypothalamic zone laterally over the optic tract to the amygdala (amygdaloid body); rostrally it tapers off over the dorsal border of the olfactory tubercle, caudally it ends where the internal capsule reaches the surface to form the cerebral peduncle or pes pedunculi. Notable among its polymorphic cell population is the large-celled basal nucleus of Meynert. These magnocellular elements within the substantia i. Are present in the medial septum and the diagonal band of Broca, but occur in largest numbers ventral to the globus pallidus. Histochemical evidence indicates that magnocellular elements distribute cholinergic fibres widely in the cerebral cortex and that these cells undergo selective degeneration in Alzheimer's disease. Synonym: substantia innominata. (05 Mar 2000) |
| interspongioplastic substance | An obsolete term for cytochylema. (05 Mar 2000) |
| threshold substance | Any material (e.g., glucose) that is excreted in the urine only when its plasma concentration exceeds a certain value, termed its threshold. Synonym: threshold body. (05 Mar 2000) |
| tigroid substance | The material consisting of granular endoplasmic reticulum and ribosomes that occurs in nerve cell bodies and dendrites. Synonym: basophil substance, basophilic substance, chromophil substance, Nissl bodies, Nissl granules, substantia basophilia, tigroid bodies, tigroid substance. (05 Mar 2000) |
| ergastic substance | Metabolically inert products of photosynthesis, such as starch grains and fat globules. (18 Nov 1997) |