| prostaglandin R2 D-isomerase | <enzyme> Prostaglandin d synthase and pgd synthase were non-print entry terms to prostaglandin synthase 1983-91 Registry number: EC 5.3.99.2 Synonym: prostaglandin endoperoxide d-isomerase, prostaglandin h2 d-isomerase, pgd2 isomerase, prostaglandin d2-isomerase, prostaglandin d2 isomerase, pgd synthetase, pgr2 d-isomerase, prostaglandin d synthase, pgd synthase, pgd2 synthase, prostaglandin d2 synthase (26 Jun 1999) |
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| prostaglandin-E synthase | <enzyme> Converts pgh to pge; part of prostaglandin synthase complex Registry number: EC 5.3.99.3 Synonym: prostaglandin r2 e-isomerase, endoperoxide isomerase, prostaglandin endoperoxide e isomerase, prostaglandin h2 e-isomerase, pge2 isomerase, prostaglandin e2 isomerase, pgr2 e-isomerase, prostaglandin h2-prostaglandin e2 isomerase, prostaglandin e isomerase (26 Jun 1999) |
| prostaglandin-E2 9-reductase | <enzyme> Catalyses reversibly an nad+ dependent oxidation of the 9alpha-hydroxyl group of 15-keto-13,14-dihydro-pgf2alpha to 15-keto-13,14-dihydro-pge2; also acts on pga1; sequence data indicates that it is identical with carbonyl reductase (NADPH) (EC 1.1.1.184) Registry number: EC 1.1.1.189 Synonym: 9-ketoprostaglandin reductase, prostaglandin-9-hydroxydehydrogenase, pge2 9-ketoreductase, pge 9-ketoreductase, prostaglandin e2-9-oxoreductase, prostaglandin 9-ketoreductase, prostaglandin e2-9-ketoreductase, 9-hydroxy-pg dehydrogenase, 9-hydroxyprostaglandin dehydrogenase, pge2 9-reductase (26 Jun 1999) |
| prostaglandin-F synthase | <enzyme> Catalyses conversion of pgd2 to pgf2alpha; also converts pgh2 to pgf2alpha Registry number: EC 1.1.1.188 Synonym: pgd2 11-keto reductase, pgf synthetase, pgf synthase, prostaglandin d2-NADPH-dependent ketoreductase, prostaglandin f synthetase, pgf2alpha synthase, prostaglandin d2 11-keto reductase (26 Jun 1999) |
| prostaglandins | A group of compounds derived from unsaturated 20-carbon fatty acids, primarily arachidonic acid, via the cyclooxygenase pathway. They are extremely potent mediators of a diverse group of physiological processes. (12 Dec 1998) |
| prostaglandins a | (13e,15s)-15-hydroxy-9-oxoprosta-10,13-dien-1-oic acid (pga(1)); (5z,13e,15s)-15-hydroxy-9-oxoprosta-5,10,13-trien-1-oic acid (pga(2)); (5z,13e,15s,17z)-15-hydroxy-9-oxoprosta-5,10,13,17-tetraen-1-oic acid (pga(3)). A group of naturally occurring secondary prostaglandins derived from pge. Pga(1) and pga(2) as well as their 19-hydroxy derivatives are found in many organs and tissues. (12 Dec 1998) |
| prostaglandins a, synthetic | Analogs or derivatives of prostaglandin a that do not occur naturally in the body. They do not include the product of the chemical synthesis of hormonal pga. (12 Dec 1998) |
| prostaglandins b | Physiologically active prostaglandins found in many tissues and organs. They are potent pressor substances and have many other physiological activities. (12 Dec 1998) |
| prostaglandins d | Physiologically active prostaglandins found in many tissues and organs. They show pressor activity, are mediators of inflammation, and have potential antithrombotic effects. (12 Dec 1998) |
| prostaglandins e | (11 alpha,13e,15s)-11,15-dihydroxy-9-oxoprost-13-en-1-oic acid (pge(1)); (5z,11 alpha,13e,15s)-11,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid (pge(2)); and (5z,11 alpha,13e,15s,17z)-11,15-dihydroxy-9-oxoprosta-5,13,17-trien-1-oic acid (pge(3)). Three of the six naturally occurring prostaglandins. They are considered primary in that no one is derived from another in living organisms. Originally isolated from sheep seminal fluid and vesicles, they are found in many organs and tissues and play a major role in mediating various physiological activities. (12 Dec 1998) |
| prostaglandins e, synthetic | Analogs or derivatives of prostaglandins e that do not occur naturally in the body. They do not include the product of the chemical synthesis of hormonal pge. (12 Dec 1998) |
| prostaglandins f | (9 alpha,11 alpha,13e,15s)-9,11,15-trihydroxyprost-13-en-1-oic acid (pgf(1 alpha)); (5z,9 alpha,11,alpha,13e,15s)-9,11,15-trihydroxyprosta-5,13-dien-1-oic acid (pgf(2 alpha)); (5z,9 alpha,11 alpha,13e,15s,17z)-9,11,15-trihydroxyprosta-5,13,17-trien-1-oic acid (pgf(3 alpha)). A family of prostaglandins that includes three of the six naturally occurring prostaglandins. All naturally occurring pgf have an alpha configuration at the 9-carbon position. They stimulate uterine and bronchial smooth muscle and are often used as oxytocics. (12 Dec 1998) |
| prostaglandins f, synthetic | Analogs or derivatives of prostaglandins f that do not occur naturally in the body. They do not include the product of the chemical synthesis of hormonal pgf. (12 Dec 1998) |
| prostaglandins g | A group of physiologically active prostaglandin endoperoxides. They are precursors in the biosynthesis of prostaglandins and thromboxanes. most frequently encountered member of this group is the prostaglandin g2. (12 Dec 1998) |
| prostaglandins h | A group of physiologically active prostaglandin endoperoxides. They are precursors in the biosynthesis of prostaglandins and thromboxanes. The most frequently encountered member of this group is the prostaglandin h2. (12 Dec 1998) |