| phonoscope | <instrument, physics> An instrument for observing or exhibiting the motions or properties of sounding bodies; especially, an apparatus invented by Konig for testing the quality of musical strings. An instrument for producing luminous figures by the vibrations of sounding bodies. Origin: Phono- + -scope. Source: Websters Dictionary (01 Mar 1998) |
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| phonoscopy | The recording made by a phonoscope. (05 Mar 2000) |
| phonosurgery | A group of operations designed to improve or alter a patient's voice. (05 Mar 2000) |
| phor- | See: phoro-. (05 Mar 2000) |
| phorate | <chemical> A cholinesterase inhibitor that is used as an insecticide. Pharmacological action: cholinesterase inhibitor, insecticide, organothiophosphate. Chemical name: Phosphorodithioic acid, O,O-diethyl S-((ethylthio)methyl) ester (12 Dec 1998) |
| phorbin | The parent hydrocarbon of chlorophyll; differs from porphin (porphyrin) in the presence of an isocyclic ring formed by the addition of a two-carbon group bridging the 13 and 15 positions of porphin (porphyrin) and by saturation of the 17-18 double bond (with realignment of conjugated double bonds). Addition of hydrocarbon side-chains in specific locations yields phorbin's characterised by prefixes; e.g., phenophorbin. (05 Mar 2000) |
| phorbol | The parent alcohol of the cocarcinogens, which are 12,13(9,9a) diesters of phorbol found in croton oil; the hydrocarbon skeleton is a cyclopropa-benzazulene; phorbol esters mimic 1,2-diacylglycerol as activators of protein kinase C. (05 Mar 2000) |
| phorbol 12,13-dibutyrate | <chemical> 1,1a,1b,4,4a,7a,7b,8,9,9a-decahydro 4a,7b,9,9a-tetrahydroxy-3-(hydroxymethyl) 1,1,6,8-tetramethyl-5h-cyclopropa(3,4)benz(1,2-e)azulen-5-one butanoic acid diester. A phorbol ester found in croton oil which, in addition to being a potent skin tumour promotor, is also an effective activator of calcium-activated, phospholipid-dependent protein kinase (protein kinase c). Due to its activation of this enzyme, phorbol 12,13-dibutyrate profoundly affects many different biological systems. Pharmacological action: carcinogens. Chemical name: Butanoic acid, 1,1a,1b,4,4a,5,7a,7b,8,9-decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-9aH-cyclopropa(3,4)benz(1,2-e)azulene-9,9a-diyl ester, (1aR-(1aalpha,1bbeta,4abeta,7aalpha,7balpha,8alpha,9beta,9aalpha))- (12 Dec 1998) |
| phorbol ester | <chemical> Polycyclic compound isolated from croton oil in which two hydroxyl groups on neighbouring carbon atoms are esterified to fatty acids. The commonest of these derivatives is phorbol myristoyl acetate (PMA). Potent co carcinogens or tumour promotors, they are diacyl glycerol analogues and activate protein kinase C irreversibly. (31 Dec 1997) |
| phorbol esters | <chemical> Tumour-promoting compounds obtained from croton oil (croton tiglium). Some of these are used in cell biological experiments as activators of protein kinase c. Pharmacological action: carcinogens. (12 Dec 1998) |
| phorbols | The parent alcohol of the tumour promoting compounds from croton oil (croton tiglium). (12 Dec 1998) |
| phoresis | Synonym: electrophoresis. 2. A biological association in which one organism is transported by another, as in the attachment of the eggs of Dermatobia hominis, a human and cattle botfly, to the legs of a mosquito, which transports them to the human, cattle, or other host in which the botfly larvae can develop. Synonym: epizoic commensalism, phoresy. Origin: G. Phoresis, a being borne (05 Mar 2000) |
| phoresy | Synonym: electrophoresis. 2. A biological association in which one organism is transported by another, as in the attachment of the eggs of Dermatobia hominis, a human and cattle botfly, to the legs of a mosquito, which transports them to the human, cattle, or other host in which the botfly larvae can develop. Synonym: epizoic commensalism, phoresy. Origin: G. Phoresis, a being borne (05 Mar 2000) |
| phoria | The relative directions assumed by the eyes during binocular fixation of a given object in the absence of an adequate fusion stimulus. See: cyclophoria, oesophoria, exophoria, heterophoria, hyperphoria, hypophoria, orthophoria. Origin: G. Phora, a carrying, motion (05 Mar 2000) |
| Phormia regina | The black blowfly, the larvae of which were formerly used in the treatment of septic wounds because they secrete a proteolytic enzyme that aids in the removal of dead tissue; it is a frequent cause of maggot infestation of sheep, depositing eggs in the wool, and is a widely distributed cold weather species that lays its eggs on dead or decaying tissues. (05 Mar 2000) |