| C type lectin | <cell biology> One of two classes of lectin produced by animal cells, the other being the S type. The C type lectins require disulphide linked cysteines and Ca ions in order to bind to a specific carbohydrate (c.f. S type lectins). The carbohydrate recognition domain of C type lectins consists of about 130 amino acids which contains 18 invariant residues in a highly conserved pattern. These invariant residues include cysteines which probably form disulphide bonds. So far, all identified C type lectins are extracellular proteins and include both Integral membrane proteins, such as the asialoglycoprotein receptor and soluble proteins. (06 Aug 1998) |
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| C type virus | <molecular biology, virology> Originally C type particles identified in mouse tumour tissue and later shown to be oncogenic RNA viruses Oncovirinae) that bud from the plasma membrane of the host cell starting as a characteristic electron dense crescent. Include feline leukaemia virus, murine leukaemia and sarcoma viruses. (18 Nov 1997) |
| haemophilus influenzae type b | The majority of type b isolates are from biotype I. The organism can cause life-threatening meningitis, primarily in children 6-12 months of age. Children with underlying disease or immunodeficiency are also at high risk for infection. A vaccine is available and recommended for children under 5 years of age. (12 Dec 1998) |
| haemophilus influenzae type b immunization | See HIB immunization, (12 Dec 1998) |
| Haemophilus influenzae type B vaccine | A conjugate of oligosaccharides of the capsular antigen of H. Influenzae type B and diphtheria CRM protein. (05 Mar 2000) |
| pre-excitation, mahaim-type | A form of pre-excitation characterised by a normal pr interval and a long qrs interval with a delta wave. (12 Dec 1998) |
| Hermansky-Pudlak syndrome type VI | An autosomal recessive deficiency of pigment in skin, hair, and eyes; in the tyrosinase negative type, there is an absence of tyrosinase; in the tyrosinase positive type, there is normal tyrosinase which cannot enter pigment cells; it is transmitted by an autosomal recessive inheritance. The compound heterozygote is normal so the two forms are not allelic. There are several types: type IA is characterised by absence of tyrosinase with life-long complete absence of melanin, marked photophobia, and nystagmus. Type IB, yellow albinism with low or absent tyrosinase; improves with age. Type II, with normal tyrosinase activity is the most common; hair darkens and nevi and freckles develop. Type III is characterised by absent tyrosinase but pigmentation of the iris in the first decade. Type IV in Africans with normal tyrosinase. Type V with red hair. Type VI, Hermansky-Padlak syndrome, with haemorrhage due to platelet deficiency and low to absent tyrosinase. Synonym: Hermansky-Pudlak syndrome type VI. (05 Mar 2000) |
| herpes simplex type 1 | A virus that causes cold sores and fever blisters. (12 Dec 1998) |
| herpes simplex type 2 | Different from herpes simplex type 1, herpes simplex 2 causes genital herpes. (12 Dec 1998) |
| herpes simplex virus type 1 UL13 protein kinase | <enzyme> Phosphorylates icp22 and involved in the accumulation of alpha and gamma mrnas and proteins in the infected cells; aa sequence has been determined Registry number: EC 2.7.1.- Synonym: ul13 protein kinase, hsv-1, hsv-1 ul13 protein, hsv-1 ul13 pk, u(l)13 protein kinase, protein kinase ul13 (26 Jun 1999) |
| Schilling type of monocytic leukaemia | See: monocytic leukaemia. (05 Mar 2000) |
| protoporphyrinogen type III | The immediate precursor of protoporphyrin III in haem biosynthesis; elevated in cases of variegate porphyria. (05 Mar 2000) |
| protoporphyrinogen type III oxidase | A mitochondrial enzyme that uses O2 to convert protoporphyrinogen type III to protoporphyrin type III in haem biosynthesis; a deficiency of this enzyme is associated with variegate porphyria. (05 Mar 2000) |
| protoporphyrin type III | 2,7,12,18-Tetramethyl-3,8-divinylporphin-13,17dipropionic acid;the principal protoporphyrin found in nature (one of 15 possible isomers), characterised by the presence of 4 methyl groups, 2 vinyl groups, and 2 propionic acid side chains; a porphyrin derivative that, with iron, forms the haem of haemoglobin and the prosthetic groups of myoglobin, catalase, cytochromes, etc. (05 Mar 2000) |
| P-type ATPase | <enzyme> One of three major classes of ion transport ATPases, characterised by vanadate sensitivity and a phosphorylated intermediate. The archetype is the sodium pump. See: F-type ATPase, V-type ATPase. (18 Nov 1997) |