| osteoarthritis |
is the most common form of arthritis affecting more than 40 million Americans. It is characterized by joint degeneration, loss of cartilage, alterations of subchondrial bone and damage to the extra-cellular matrix. There is a 35 per cent incidence of weakness in the knees as early as age 30. Its incidence increases dramatically with age, affecting 80 per cent of all persons over the age of 50.
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