| nonfilament polymorphonuclear leukocyte | <haematology> A neutrophil, basophil, or eosinophil that is not completely matured, i.e., the lobes of the nuclei remain connected with bands of chromatin, in contrast to the thin strands observed in mature cells. (05 Mar 2000) |
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| nongranular leukocyte | <haematology> A general, non-specific term frequently used with reference to lymphocytes, monocytes, and plasma cells; although the cytoplasm of a lymphocyte or monocyte contains tiny granules, it is nongranular in comparison with that of a neutrophil, basophil, or eosinophil. See: leukocyte. Synonym: agranular leukocyte. (05 Mar 2000) |
| nonmotile leukocyte | <haematology> A term sometimes used with reference to lymphocytes, monocytes, and plasma cells; although such forms actually have some degree of motility, they are nonmotile in comparison with the actively ameboid, neutrophilic, basophilic, and eosinophilic leukocyte's. (05 Mar 2000) |
| oxyphilic leukocyte | A polymorphonuclear leukocyte characterised by many large or prominent, refractile, cytoplasmic granules that are fairly uniform in size and bright yellow-red or orange when treated with Wright's or similar stains; the nuclei are usually larger than those of neutrophils, do not stain as deeply, and characteristically have two lobes (a third lobe is sometimes interposed on the connecting strand of chromatin); these leukocyte's are motile phagocytes with distinctive antiparasitic functions. Synonym: acidophilic leukocyte, eosinocyte, eosinophil, eosinophile, oxyphil, oxyphile, oxyphilic leukocyte. (05 Mar 2000) |
| transitional leukocyte | Old term for a monocyte. (05 Mar 2000) |
| endothelial leukocyte | Old term for a monocyte, a type of leukocyte thought to be derived from reticuloendothelial tissue. (05 Mar 2000) |
| endothelial-leukocyte adhesion molecule | 115,000 Mw molecule on the surface of endothelial cells that is involved in blood leukocyte attachment to vessel walls as well as emigration from the vessels into the tissues. (05 Mar 2000) |
| eosinophilic leukocyte | A polymorphonuclear leukocyte characterised by many large or prominent, refractile, cytoplasmic granules that are fairly uniform in size and bright yellow-red or orange when treated with Wright's or similar stains; the nuclei are usually larger than those of neutrophils, do not stain as deeply, and characteristically have two lobes (a third lobe is sometimes interposed on the connecting strand of chromatin); these leukocyte's are motile phagocytes with distinctive antiparasitic functions. Synonym: acidophilic leukocyte, eosinocyte, eosinophil, eosinophile, oxyphil, oxyphile, oxyphilic leukocyte. (05 Mar 2000) |
| Turk's leukocyte | A relatively large, immature cell with certain morphologic features resembling those of a plasma cell, although the nuclear pattern is similar to that of a myeloblast; found in circulating blood only in pathologic conditions. Synonym: irritation cell, Turk's leukocyte. (05 Mar 2000) |
| filament polymorphonuclear leukocyte | Any mature polymorphonuclear leukocyte, especially a neutrophilic leukocyte, in which the lobes of the nucleus are interconnected with a thin strand or filament of chromatin. (05 Mar 2000) |
| leukocyte | <haematology> White corpuscles in the blood. They are spherical, colourless and nucleated masses involved with host defenses. Normal white blood cell counts are variable with age and sex. Normal adult range is 4, 500 to 11,000 cells per cubic millimetre of blood. Slightly higher counts are seen in children. Elevated counts can be seen in cases of inflammation and infection. See: leucocytes, basophils, coelomocytes, eosinophils, haemocytes, lymphocytes, neutrophils, monocytes. Acronym: WBC (13 Nov 1997) |
| leukocyte adherence assay test | A test to detect the ability of leukocytes to adhere to bacteria, performed in vitro using nylon fibres to measure adherence. (05 Mar 2000) |
| leukocyte adherence inhibition test | Test for cell-mediated antitumour immunity and related serum blocking factors based on the finding that leukocytes from cancer patients, but not from controls, when mixed in vitro with antigenic extracts of tumours of the same histological type, undergo a diminution in their normal adherence to glass surfaces. Sera from tumour-bearing patients block the lai reaction of their own leukocytes or those of other patients with the same type of tumour. (12 Dec 1998) |
| leukocyte adhesion deficiency | An inherited disorder (autosomal recessive) in which there is a defective CD18 adherence complex that disturbs leukocyte chemotaxis. It is characterised by recurrent bacterial infections and impaired wound healing. (05 Mar 2000) |
| leukocyte-adhesion deficiency syndrome | <syndrome> Rare, autosomal recessive disorder caused by deficiency of the beta 2 integrin receptors (receptors, leukocyte-adhesion) comprising the CD11/CD18 family of glycoproteins. The syndrome is characterised by abnormal adhesion-dependent functions, especially defective tissue emigration of neutrophils, leading to recurrent infection. (12 Dec 1998) |