| Ewing's sarcoma | <oncology, tumour> A malignant primary bone tumour that arises most commonly in the first three decades of life. It is highly malignant (prone to spread) and often requires treatment with some combination of radiation therapy and chemotherapy. (27 Sep 1997) |
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| juxtacortical osteogenic sarcoma | <tumour> A form of osteogenic sarcoma of relatively low malignancy, probably arising from the periosteum and initially involving cortical bone and adjacent connective tissue, which occurs in middle-aged as well as young adults and most commonly affects the lower part of the femoral shaft. Synonym: periosteal sarcoma. (05 Mar 2000) |
| fascicular sarcoma | <tumour> A malignant neoplasm, believed to be of mesenchymal origin, composed of elongated, spindle-shaped cells. Synonym: fascicular sarcoma. (05 Mar 2000) |
| undifferentiated sarcoma of liver | <radiology> Kiddies, age 4 - 15 yrs, M = F, complex hepatic mass, often hypovascular, most in right lobe, large ( more than 10 cm), ** Differential diagnosis: embryonal rhabdomyosarcoma (12 Dec 1998) |
| Kirsten sarcoma virus | <virology> A murine sarcoma inducing retrovirus, generated by passaging a murine erythoblastosis virus in newborn rats. Source of the Ki ras oncogene. (18 Nov 1997) |
| feline leukaemia-sarcoma virus complex | Viruses from cats that induce transmissible leukaemia or transmissible fibrosarcoma in kittens. (05 Mar 2000) |
| feline sarcoma | <oncology, tumour> An oncogene carried by one of the strains of the feline sarcoma virus (the Snyder-Theilen strain, Garden-Rasheed strain, McDonough strain). It causes the development of sarcoma tumours in cats. The normal product of the gene (as a proto-oncogene) seems to be a kinase enzyme that phosphorylates (attaches phosphate groups to) the amino acid tyrosine in polypeptides. (09 Oct 1997) |
| feline sarcoma virus | <virology> A retrovirus which carries an oncogene that causes feline sarcoma (a tumour-causing disease) in cats. (09 Oct 1997) |
| leukocytic sarcoma | <haematology> An acute or chronic disease of unknown cause in man and other warm blooded animals that involves the blood forming organs, is characterised by an abnormal increase in the number of leucocytes in the tissues of the body with or without a corresponding increase of those in the circulating blood and is classified according of the type leucocyte most prominently involved. (18 Nov 1997) |
| lymphatic sarcoma | <tumour> Obsolete term for lymphosarcoma. (05 Mar 2000) |
| abortion, multiple | Couples who have had 2 or more miscarriages (spontaneous abortions) have about a 5% chance that one member of the couple is carrying a chromsome translocation responsible for the miscarriages. (12 Dec 1998) |
| advanced multiple-beam equalization radiography | A variant of scanning equalization radiography using several X-ray beams. (05 Mar 2000) |
| amyloidosis of multiple myeloma | Foci of amyloidosis in mesenchymal tissues of some persons with multiple myeloma; no direct relation between amyloid and Bence Jones protein is conclusively known. (05 Mar 2000) |
| cancer, multiple myeloma | A bone marrow cancer involving a type of white blood cell called a plasma (or myeloma) cell. The tumour cells can form a single collection (a plasmacytoma) or many tumours (multiple myeloma). Plasma cells are part of the immune system and make antibodies. Because patients have an excess of identical plasma cells, they have too much of one type of antibody. As myeloma cells increase in number, they damage and weaken the bones, causing pain and often fractures. When bones are damaged, calcium is released into the blood leading to hypercalcaemia (excess calcium in the blood) and that causes loss of appetite, nausea, thirst, fatigue, muscle weakness, restlessness, and confusion. Myeloma cells prevent the bone marrow from forming normal plasma cells and other white blood cells important to the immune system so patients may not be able to fight infections. The cancer cells can also prevent the growth of new red blood cells, causing anaemia. Excess antibody proteins and calcium may prevent the kidneys from filtering and cleaning the blood properly Cancer, non-Hodgkin's lymphoma: A lymphoma is a cancer that develops in the lymphatic system. The most common symptom of non-Hodgkin's lymphomas is a painless swelling in the lymph nodes in the neck, underarm, or groin. Non-Hodgkin's lymphomas are diagnosed with a biopsy of an enlarged lymph node. Follow-up examinations are important after lymphoma treatment. Most relapses occur in the first 2 years after therapy. (12 Dec 1998) |
| chromosomes in multiple miscarriages | Couples who have had more than one miscarriage (spontaneous abortion) have about a 5% chance that one member of the couple is carrying a chromsome translocation responsible for the miscarriages. (12 Dec 1998) |