| light chain-related amyloidosis | A form of primary amyloidosis in which the fibrillar amyloid deposits are derived from the amino terminal variable region of the light chains of immunoglobulin; seen in B-lymphocyte and plasma-cells dyscrasias. (05 Mar 2000) |
|---|---|
| long chain | In bacteriology, a continuous line of more than eight cells. (05 Mar 2000) |
| long-chain 3-hydroxyacyl CoA dehydrogenase | <enzyme> Deficiency may cause some cases of hypoglycaemic 3-hydroxydicarboxylic aciduria Registry number: EC 1.1.1.211 Synonym: l-chad (26 Jun 1999) |
| long-chain-acyl-CoA dehydrogenase | <enzyme> Flavoprotein; forms with another flavoprotein plus EC 1.5.5.1 a system reducing ubiquinone and other acceptors Registry number: EC 1.3.99.- Synonym: lc-acyl-CoA dehydrogenase, long-chain-acyl-coenzyme a dehydrogenase, very-long-chain acyl-CoA dehydrogenase, vlcad (26 Jun 1999) |
| long-chain-alcohol dehydrogenase | <enzyme> Catalyses reversibly the oxidation of a long-chain alcohol in the presence of nad to a long-chain acid anion and NADH Registry number: EC 1.1.1.192 Synonym: fatty alcohol-nad+ oxidoreductase (26 Jun 1999) |
| long-chain-alcohol O-fatty-acyltransferase | <enzyme> Catalyses the final step in biosynthesizing storage liquid waxes from long chain fatty acyl CoA and fatty alcohols; forming predominantly c42 wax esters Registry number: EC 2.3.1.75 Synonym: acyl-coenzyme a-alcohol transacylase, aca transacylase, acyl-CoA-alcohol transacylase, wax-ester synthase (26 Jun 1999) |
| long-chain-fatty-acid-(acyl-carrier-protein) ligase | <enzyme> Fatty acid, acyl-carrier-protein-sh and ATP gives acyl-(acyl-carrier-protein), AMP and ppi Registry number: EC 6.2.1.20 Synonym: fatty acid-acyl carrier protein ligase (AMP), acyl-(acyl-carrier-protein)synthetase, aacp synthetase, fatty acyl-acyl carrier protein synthase, vibrio harveyi, acyl-(acyl-carrier-protein) synthetase, acyl-acp synthetase (26 Jun 1999) |
| long-chain-fatty-acid-CoA ligase | <enzyme> Fatty acid thiokinase (long-chain), a ligase forming acyl-CoA, AMP, and pyrophosphate from long-chain fatty acids, ATP, and coenzyme A. Activity is independent of phosphatidylcholine Registry number: EC 6.2.1.3 Synonym: acyl-activating enzyme, dodecanoyl-CoA synthetase, fatty acid thiokinase (long chain), acid-coenzyme a ligase, fatty acid-CoA ligase, acyl-CoA synthetase, acyl-CoA ligase, coash ligase, ciprofibroyl-CoA synthetase, pristanoyl-CoA synthetase, palmityl CoA synthetase, palmitoyl CoA synthetase, palmitoyl CoA ligase, fatty acyl-CoA synthetase, very long chain fatty acid acyl-CoA synthetase, vlcfa acyl-CoA synthetase, nafenopin-CoA ligase, palmitoyl-CoA synthase, faa2 gene product, faa2p protein, vlacs enzyme (26 Jun 1999) |
| long-chain-fatty-acyl-glutamate deacylase | <enzyme> Lca aminoacylase I almost specific to l-glutamate-containing lipoamino acids; lca aminoacylase II acts on fatty acyl amino acids with chain lengths between c11 and c16 Registry number: EC 3.5.1.55 Synonym: lca aminoacylase I, lca aminoacylase II, n-long chain acyl aminoacylase (26 Jun 1999) |
| LTDH short chain dehydrogenase | <enzyme> Has been sequenced; responsible for methotrexate resistance; isolated from leishmania sp. Registry number: EC 1.3.- Synonym: ltdh gene product, pteridine reductase 1, ptr1 gene product, hmtx(r) gene product (26 Jun 1999) |
| aaa disease | Endemic anaemia of ancient Egypt, ascribed in the Papyrus Ebers to intestinal infestation with ancylostoma; now called ancylostomiasis. (05 Mar 2000) |
| ABO haemolytic disease of the newborn | Erythroblastosis foetalis due to maternal-foetal incompatibility with respect to an antigen of the ABO blood group; the foetus possesses A or B antigen which is lacking in the mother, and the mother produces immune antibody which causes haemolysis of foetal erythrocytes. (05 Mar 2000) |
| accumulation disease | A disease characterised by abnormal accumulation of a metabolic product in certain cells and tissues; examples include the mucopolysaccharidoses, lipoidoses. (05 Mar 2000) |
| Acosta's disease | A condition that results from prolonged exposure to high altitude. Symptoms include a continuous dry cough, shortness of breath, poor exercise tolerance, dizziness, headache, sleep difficulty, anorexia, confusion, fatigue and a rapid pulse. Treatment includes the immediate movement to a lower altitude. Prophylaxis has been accomplished successfully with the use of acetazolamide (Diamox). (27 Sep 1997) |
| acquired immunodeficiency disease | Acquired immunodeficiency disease: Disease caused by infection with the human immunodeficiency virus (HIV). (12 Dec 1998) |