| genes, T-cell receptor gamma | DNA sequences encoding the gamma chain of the T-cell receptor. The human gamma-chain locus is organised similarly to the tcr beta-chain locus. (12 Dec 1998) |
|---|---|
| genes, vif | DNA sequences that form the coding region for the vif (virion infectivity factor) protein that is important for the generation of infectious virions in human immunodeficiency virus (HIV). The former name of this gene was sor (short open reading frame). (12 Dec 1998) |
| genes, viral | The hereditary material of viruses, consisting in all DNA and some RNA viruses of a single molecule of nucleic acid, and in some RNA viruses of several separate pieces of RNA. (12 Dec 1998) |
| genes, vpr | DNA sequences that form the coding region for a trans-activator protein that specifies rapid growth in human immunodeficiency virus (HIV). Vpr is short for viral protein r, where r is undefined. (12 Dec 1998) |
| genes, vpu | DNA sequences that form the coding region for the HIV-1 regulatory protein vpu (viral protein u) that greatly increases the export of virus particles from infected cells. The vpu genes are not present in HIV-2 or siv. (12 Dec 1998) |
| genes, wilms' tumour | Tumour suppressor genes located in the 11p13 region on the short arm of human chromosome 11. The absence of these genes is associated with the formation of wilms' tumour. (12 Dec 1998) |
| VH and VL genes/domains | VH and VL genes define in part the sequences of the variable heavy and light regions of immunoglobulin molecules. VH and VL domains are the regions of amino acid sequence so defined. J genes and, in the case of the heavy chain, a D gene (D=diversity) also define these regions. Gene rearrangement also plays a role in determining the sequences in which the genes are joined as the DNA of the immunoglobulin producing cell matures. (18 Nov 1997) |
| mimic genes | Nonallelic (independent) gene's with closely similar effects, e.g., elliptocytosis. (05 Mar 2000) |
| homeotic genes | A group of genes that regulate the development of the body parts by defining the boundaries of the several regions. (05 Mar 2000) |
| housekeeping genes | Genes that are generally always expressed and thought to be involved in routine cellular metabolism. (05 Mar 2000) |
| SOS genes | A group of genes involved in DNA repair, often induced by damage severe enough to cause stoppage of DNA synthesis. (05 Mar 2000) |
| split genes | Genes where the genomic sequences are interrupted by intervening sequences (introns) that are spliced out of the mRNA prior to translation. (05 Mar 2000) |
| immune response genes | Gene's in the HLA-D region of the histocompatibility complex of human chromosome 6 which control the immune response to specific antigens. (05 Mar 2000) |
| transfer genes | Gene's carried by a conjugative plasmid, essential for fertility and establishment of the bacterial donor state. (05 Mar 2000) |
| absorptive cells of intestine | Cell's on the surface of villi of the small intestine and the luminal surface of the large intestine that are characterised by having microvilli on their free surface. (05 Mar 2000) |