| 'Greek letter alpha' | angular acceleration; first [carbon atom next to the carbon atom bearing the active group in organic... |
|---|---|
| APCKD | adult-type polycystic kidney disease |
| ATCC | American Type Culture Collection |
| ATD | Alzheimer-type dementia; androstatrienedione; anthropomorphic test dummy; antithyroid drug; aqueous ... |
| beta [Greek letter beta] | an anomer of a carbohydrate; buffer capacity; carbon separated from a carboxyl by one other carbon i... |
| genes, rag-1 | Genes involved in activating the enzyme vdj recombinase. Rag-1 is located on chromosome 11 in humans (chromosome 2 in mice) and is expressed exclusively in maturing lymphocytes. (12 Dec 1998) |
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| genes, ras | Family of retrovirus-associated DNA sequences (ras) originally isolated from harvey (h-ras, ha-ras, rash) and kirsten (k-ras, ki-ras, rask) murine sarcoma viruses. Ras genes are widely conserved among animal species and sequences corresponding to both h-ras and k-ras genes have been detected in human, avian, murine, and non-vertebrate genomes. The closely related n-ras gene has been detected in human neuroblastoma and sarcoma cell lines. All genes of the family have a similar exon-intron structure and each encodes a p21 protein. (12 Dec 1998) |
| genes, recessive | Genes that are reflected in the phenotype only in the homozygous state. (12 Dec 1998) |
| genes, regulator | Genes which regulate or circumscribe the activity of other genes; specifically, genes which code for proteins (repressors or activators) which regulate the genetic transcription of the structural genes and/or regulatory genes. (12 Dec 1998) |
| genes, reporter | Genes whose expression is easily detectable and therefore used to study promoter activity at many positions in a target genome. In recombinant DNA technology, these genes may be attached to a promoter region of interest. (12 Dec 1998) |
| genes, retinoblastoma | Tumour suppressor genes located on human chromosome 13 in the region 13q14 and coding for a family of phosphoproteins with molecular weights ranging from 104 kD to 115 kD. One copy of the wild-type rb gene is necessary for normal retinal development. Loss or inactivation of both alleles at this locus results in retinoblastoma. (12 Dec 1998) |
| genes, rev | DNA sequences that form the coding region for a protein that regulates the expression of the viral structural and regulatory proteins in human immunodeficiency virus (HIV). Rev is short for regulator of virion. (12 Dec 1998) |
| genes, src | Retrovirus-associated DNA sequences (src) originally isolated from the rous sarcoma virus (rsv). The proto-oncogene src (c-src) codes for a protein that is a member of the tyrosine kinase family and was the first proto-oncogene identified in the human genome. The human c-src gene is located at 20q12-13 on the long arm of chromosome 20. (12 Dec 1998) |
| genes, structural | Genes that code for proteins required for the enzymatic and structural functions of cells. They include developmental and differentiated genes. (12 Dec 1998) |
| genes, structural, bacterial | DNA sequences that code for RNA and for the proteins required for the enzymatic and structural function of bacterial cells. (12 Dec 1998) |
| genes, structural, helminth | DNA sequences that code for RNA and for the proteins required for the enzymatic and structural function of helminthic cells. (12 Dec 1998) |
| genes, structural, insect | DNA sequences that code for RNA and for proteins required for the enzymatic and structural function of insect cells. (12 Dec 1998) |
| genes, structural, neoplasm | DNA sequences that code for RNA and for the proteins required for the enzymatic and structural function of neoplastic cells. (12 Dec 1998) |
| genes, structural, plant | DNA sequences that code for RNA and for the proteins required for the enzymatic and structural function of plant cells. (12 Dec 1998) |
| genes, structural, protozoan | DNA sequences that code for RNA and for the proteins required for the enzymatic and structural function of protozoan cells. (12 Dec 1998) |