| drug pathogenesis | The production of morbid symptoms by drugs. (05 Mar 2000) |
|---|---|
| drug, prescription | A drug requiring a prescription, a physician's order. By comparison with an over-the-counter drug. (12 Dec 1998) |
| drug psychosis | Psychosis following or precipitated by ingestion of a drug, e.g., LSD. (05 Mar 2000) |
| drug rash | Adverse cutaneous reactions caused by ingestion, parenteral use, or local application of a drug. These may assume various morphologic patterns and produce various types of lesions. (12 Dec 1998) |
| drug residues | Drugs and their metabolites which are found in the edible tissues and milk of animals after their medication with specific drugs. This term can also apply to drugs found in adipose tissue of humans after drug treatment. (12 Dec 1998) |
| drug resistance | The ability of bacteria and other microorganisms to withstand a drug to which they were once sensitive (and were once stalled or killed outright). (12 Dec 1998) |
| drug resistance, microbial | The ability of microorganisms, especially bacteria, to resist or to become tolerant to chemotherapeutic agents, antimicrobial agents, or antibiotics. This resistance may be acquired through plasmids containing resistance factors (r factors). (12 Dec 1998) |
| drug resistance, multiple | Simultaneous resistance to a broad spectrum of structurally and functionally distinct drugs following exposure to a single agent. It is thought to result from the overexpression of genes encoding an integral plasma membrane protein, p-glycoprotein. (12 Dec 1998) |
| drug resistance, neoplasm | Resistance or diminished response of a neoplasm to an antineoplastic agent in humans, animals, or cell or tissue cultures. (12 Dec 1998) |
| drug resistant | Unresponsive to the desired effects of drugs or other therapy for example: irradiation cytotoxic agents or hormones. Drug resistance of cells within tumours is probably the major cause of treatment failure. (16 Dec 1997) |
| drug screening | Preclinical testing of drugs in experimental animals or in vitro for their biological and toxic effects and potential clinical applications. (12 Dec 1998) |
| drug screening assays, antitumour | Methods of investigating the effectiveness of anticancer cytotoxic drugs and biologic inhibitors. These include in vitro cell-kill models and cytostatic dye exclusion tests as well as in vivo measurement of tumour growth parameters in laboratory animals. (12 Dec 1998) |
| drug side effect | An often undesirable effect that occurs in association with the use of a particular medication. Examples of common drug side effects include: nausea, vomiting, sedation, dizziness, headache and weakness. Drug side effects that occur in 1% or more, of patients taking a particular medication are considered to be causally related to the use of that medication. (27 Sep 1997) |
| drug tetanus | Tonic spasms caused by strychnine or other tetanic. Synonym: toxic tetanus. (05 Mar 2000) |
| drug therapy, combination | Drug therapy with two or more drugs given separately for a combined effect. (12 Dec 1998) |