| prospective, randomised, double-blind clinical trial | <statistics> A clinical trial in which the method for analysing data has been specified in the protocol before the study has begun (prospective), the patients have been randomly assigned to receive either the study drug or alternative treatment, and in which neither the patient nor the physician conducting the study know which treatment is being given to the patient. (13 Nov 1997) |
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| psychology, clinical | The branch of psychology concerned with psychological methods of recognizing and treating behaviour disorders. (12 Dec 1998) |
| human clinical trial | <pharmacology> Controlled clinical studies in human volunteers to test the safety and efficacy of pharmaceutical candidates. There are usually three distinct phases of human clinical testing: Phases I, II, and III. Phase I trials are safety studies of volunteers, usually healthy controls. Phase II trials are studies to confirm safety and study optimum dose and initial efficacy. Phase III trials are studies to prove safety and efficacy in a specific patient population. (14 Nov 1997) |
| decision support systems, clinical | Computer-based information systems used to integrate clinical and patient information and provide support for decision-making in patient care. (12 Dec 1998) |
| disease, clinical | A disease with clinical signs and symptoms that can be recognised. As distinct from a subclinical illness without recognizable clinical manifestations. Diabetes, for example, can be subclinical in a person before emerging as a clinical disease. (12 Dec 1998) |
| in clinical parlance | The term often refers to the posterior funiculus of the spinal cord. (05 Mar 2000) |
| epidemiology, clinical | Epidemiology focused specifically upon patients. (12 Dec 1998) |
| anterior white commissure | A narrow band of white substance bordering on the anterior median fissure of the spinal cord in front of the anterior gray commissure, and consisting of nerve fibres crossing over from one half of the spinal cord to the other. Synonym: commissura alba, anterior white commissure, commissura ventralis alba, ventral white column. (05 Mar 2000) |
| blue white colour selection | <molecular biology, procedure> Method for identifying bacterial clones containing plasmids with inserts. Many modern vectors have their polycloning site within a part of the LacZ gene encoding _ galactosidase, which provides _ complementation in an appropriate mutant E. Coli strain. This means that a re ligated (empty) vector will produce blue colonies when grown on plates containing IPTG and X gal, but colonies with a substantial insert in their plasmid's polycloning site are unable to produce functional _ galactosidase and so produce white colonies. (16 Dec 1997) |
| Bouffardi's white mycetoma | <dermatology> A form of mycetoma common in India and found occasionally in Somalia, caused by the organism Streptomyces somaliensis; in this variety, the muscles, tendons, and bones of the foot are destroyed by the disease process; numerous draining sinuses discharge yellowish grains, clustered like fish roe. (05 Mar 2000) |
| Brumpt's white mycetoma | Mycetoma caused by Pseudallescheria boydii, occurring in temperate and subtropical areas in India; small, white to yellow, hard to soft granules are discharged through the draining sinuses. (05 Mar 2000) |
| ventral white column | A narrow band of white substance bordering on the anterior median fissure of the spinal cord in front of the anterior gray commissure, and consisting of nerve fibres crossing over from one half of the spinal cord to the other. Synonym: commissura alba, anterior white commissure, commissura ventralis alba, ventral white column. (05 Mar 2000) |
| matter, white | The part of the brain that contains myelinated nerve fibres. The white matter is white because it is the colour of myelin, the insulation covering the nerve fibres. The white matter is as opposed to the gray matter (the cortex of the brain which contains nerve cell bodies). (12 Dec 1998) |
| May-White syndrome | <syndrome> Progressive myoclonus epilepsy with lipomas, deafness, and ataxia; probably a familial form of mitochondrial encephalomyopathy. (05 Mar 2000) |
| Vincent's white mycetoma | Mycetoma caused by Actinomadura madurae and occurring in North Africa, India, the Argentine, and Cuba. (05 Mar 2000) |