| NINCDS/ADRDA | National Institute of Neurological and Communicative Diseases and Stroke/Alzheimer's Disease and Rel... |
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| OND | Ophthalmic Nursing Diploma; orbitonasal dislocation; other neurological disorders |
| PAIN | pyoderma gangrenosum, aphthous stomatitis, inflammatory eye disease, erythema nodosum [disorders ass... |
| SADD | Short-Alcohol Dependence Data [questionnaire]; standardized assessment of depressive disorders; Stud... |
| SADS | Schedule for Affective Disorders and Schizophrenia |
| yeast artificial chromosome | <molecular biology> A vector system that allows extremely large segments of DNA to be cloned. Useful in chromosome mapping, contiguous yeast artificial chromosomes covering the whole Drosophila genome and certain human chromosomes are available. Acronym: YAC (15 Nov 1997) |
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| Z chromosome | <genetics> This is a sex chromosome in certain animals such as chickens and moths. In the Z chromosome karyotype, females are heterogametic, so males are ZZ and females are WZ. (11 May 1997) |
| unpaired chromosome | A chromosome existing without its normal homologous chromosome; at the reduction division of gametogenesis an accessory chromosome is likely to be included in one daughter cell and not in the other, but may be lost completely by lagging behind on the equatorial plate. Synonym: monosome, odd chromosome, unpaired allosome, unpaired chromosome. (05 Mar 2000) |
| lampbrush chromosome | <cell biology> Large chromosomes (as long as 1mm), actually meiotic bivalents, seen during prophase of the extended meiosis in the oocytes of some Amphibia. Segments of DNA form loops in pairs along the sides of the sister chromosomes, giving them a brush like appearance. These loops are not permanent structures but are formed by the unwinding of chromomeres and represent sites of very active RNA synthesis. (27 Jun 1999) |
| late replicating chromosome | A chromosome (often anomalous) that is shown, e.g., by incorporation of a labelled nucleotide, to undergo delayed duplication preliminary to mitosis; formerly used as a means of distinguishing members of a group of chromosome's. (05 Mar 2000) |
| fragile x chromosome | X chromosome with a fragile site associated with a frequent form of mental retardation. The fragile X chromosome was first sighted by Herbert A. Lubs in 1969. The fragile X is also called FRAXA (the second A signifies it was the first FRAgile site found on the X chromosome). It is due a trinucleotide repeat (a recurring motif of 3 bases) in the DNA at that spot. (12 Dec 1998) |
| adjustment disorders | Maladaptive reactions to identifiable psychosocial stressors occurring within a short time after onset of the stressor. They are manifested by either impairment in social or occupational functioning or by symptoms (depression, anxiety, etc.) that are in excess of a normal and expected reaction to the stressor. (12 Dec 1998) |
| affective disorders | A class of mental disorder's characterised by a disturbance in mood. (05 Mar 2000) |
| affective disorders, psychotic | Disorders in which the essential feature is a severe disturbance in mood (depression, anxiety, elation, and excitement) accompanied by psychotic symptoms such as delusions, hallucinations, gross impairment in reality testing, etc. (12 Dec 1998) |
| alcohol-related disorders | Mental disorders related or resulting from abuse or mis-use of alcohol. (12 Dec 1998) |
| amphetamine-related disorders | Disorders related or resulting from use of amphetamines. (12 Dec 1998) |
| anxiety disorders | Disorders in which anxiety (persistent feelings of apprehension, tension, or uneasiness) is the predominant disturbance. (12 Dec 1998) |
| articulation disorders | Disorders of speech sound production characterised by substitution, omission, and distortion of sounds. (12 Dec 1998) |
| auditory perceptual disorders | Disorders of auditory perception manifesting as difficulties with auditory memory, speech perception and sound localization. Lesions are usually in the temporal lobe. (12 Dec 1998) |
| bowel disorders and fibre | High fibre diets help delay the progression of diverticulosis and, at least, reduce the bouts of diverticulitis. In many cases, it helps reduce the symptoms of the Irritable Bowel Syndrome ( IBS ). It is generally accepted that a diet high in fibre is protective, or at least reduces the incidence, of colon polyps and colon cancer. (12 Dec 1998) |