| L chain | <immunology> Although light chains are found in many multimeric proteins, L chain usually refers to the light chains of immunoglobulins. These are of 22 kD and of one of two types, kappa or lambda. A single immunoglobulin has identical light chains (2 kappa or 2 lamda). Light chains have one variable and one constant region. There are isotype variants of both kappa and lamda. (25 Jun 1999) |
|---|---|
| L-chain disease | bence Jones myeloma |
| L-chain myeloma | bence Jones myeloma |
| light chain | <immunology, protein> The lighter of the two types of polypeptide chains that are found in immunoglobulin and antibody molecules. Also used as a non-specific term for the smaller subunits of several multimeric proteins such as immunoglobulin, myosin, dynein, clathrin. (14 Oct 1997) |
| light chain-related amyloidosis | A form of primary amyloidosis in which the fibrillar amyloid deposits are derived from the amino terminal variable region of the light chains of immunoglobulin; seen in B-lymphocyte and plasma-cells dyscrasias. (05 Mar 2000) |
| long chain | In bacteriology, a continuous line of more than eight cells. (05 Mar 2000) |
| long-chain 3-hydroxyacyl CoA dehydrogenase | <enzyme> Deficiency may cause some cases of hypoglycaemic 3-hydroxydicarboxylic aciduria Registry number: EC 1.1.1.211 Synonym: l-chad (26 Jun 1999) |
| long-chain-acyl-CoA dehydrogenase | <enzyme> Flavoprotein; forms with another flavoprotein plus EC 1.5.5.1 a system reducing ubiquinone and other acceptors Registry number: EC 1.3.99.- Synonym: lc-acyl-CoA dehydrogenase, long-chain-acyl-coenzyme a dehydrogenase, very-long-chain acyl-CoA dehydrogenase, vlcad (26 Jun 1999) |
| long-chain-alcohol dehydrogenase | <enzyme> Catalyses reversibly the oxidation of a long-chain alcohol in the presence of nad to a long-chain acid anion and NADH Registry number: EC 1.1.1.192 Synonym: fatty alcohol-nad+ oxidoreductase (26 Jun 1999) |
| long-chain-alcohol O-fatty-acyltransferase | <enzyme> Catalyses the final step in biosynthesizing storage liquid waxes from long chain fatty acyl CoA and fatty alcohols; forming predominantly c42 wax esters Registry number: EC 2.3.1.75 Synonym: acyl-coenzyme a-alcohol transacylase, aca transacylase, acyl-CoA-alcohol transacylase, wax-ester synthase (26 Jun 1999) |
| long-chain-fatty-acid-(acyl-carrier-protein) ligase | <enzyme> Fatty acid, acyl-carrier-protein-sh and ATP gives acyl-(acyl-carrier-protein), AMP and ppi Registry number: EC 6.2.1.20 Synonym: fatty acid-acyl carrier protein ligase (AMP), acyl-(acyl-carrier-protein)synthetase, aacp synthetase, fatty acyl-acyl carrier protein synthase, vibrio harveyi, acyl-(acyl-carrier-protein) synthetase, acyl-acp synthetase (26 Jun 1999) |
| long-chain-fatty-acid-CoA ligase | <enzyme> Fatty acid thiokinase (long-chain), a ligase forming acyl-CoA, AMP, and pyrophosphate from long-chain fatty acids, ATP, and coenzyme A. Activity is independent of phosphatidylcholine Registry number: EC 6.2.1.3 Synonym: acyl-activating enzyme, dodecanoyl-CoA synthetase, fatty acid thiokinase (long chain), acid-coenzyme a ligase, fatty acid-CoA ligase, acyl-CoA synthetase, acyl-CoA ligase, coash ligase, ciprofibroyl-CoA synthetase, pristanoyl-CoA synthetase, palmityl CoA synthetase, palmitoyl CoA synthetase, palmitoyl CoA ligase, fatty acyl-CoA synthetase, very long chain fatty acid acyl-CoA synthetase, vlcfa acyl-CoA synthetase, nafenopin-CoA ligase, palmitoyl-CoA synthase, faa2 gene product, faa2p protein, vlacs enzyme (26 Jun 1999) |
| long-chain-fatty-acyl-glutamate deacylase | <enzyme> Lca aminoacylase I almost specific to l-glutamate-containing lipoamino acids; lca aminoacylase II acts on fatty acyl amino acids with chain lengths between c11 and c16 Registry number: EC 3.5.1.55 Synonym: lca aminoacylase I, lca aminoacylase II, n-long chain acyl aminoacylase (26 Jun 1999) |
| LTDH short chain dehydrogenase | <enzyme> Has been sequenced; responsible for methotrexate resistance; isolated from leishmania sp. Registry number: EC 1.3.- Synonym: ltdh gene product, pteridine reductase 1, ptr1 gene product, hmtx(r) gene product (26 Jun 1999) |
| abnormalities, drug-induced | Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment. (12 Dec 1998) |