| corticosteroid | <drug, endocrinology, pharmacology> Any of the steroids elaborated by the adrenal cortex (excluding the sex hormones of adrenal origin) in response to the release of adrenocorticotrophin or adrenocorticotropic hormone (ACTH) by the pituitary gland, to any of the synthetic equivalents of these steroids or to angiotensin II. They are divided, according to their predominant biological activity, into three major groups: glucocorticoids (e.g. Cortisol, cortisone), chiefly influencing carbohydrate, fat and protein metabolism, mineralocorticoids (for example aldosterone), affecting the regulation of electrolyte and water balance and C19 androgens. Some corticosteroids exhibit both types of activity in varying degrees and others exert only one type of effect. The corticosteroids are used clinically for hormonal replacement therapy, for suppression of ACTH secretion by the anterior pituitary, as antineoplastic, antiallergic and anti-inflammatory agents and to suppress the immune response. Synonym: adrenocortical hormone, corticoid. (13 Nov 1997) |
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| corticosteroid cream | <drug, pharmacology> This is a large group of trade name medications that contain an anti-inflammatory steroid. These cream based medications all contain either hydrocortisone in varying concentrations or a synthetic steroid with much greater potency. This type of medications is useful in the treatment of a large number of inflammatory rashes. Caution: higher potency creams can cause side effects. Examples include hydrocortisone, dexamethasone, flunisolide, fluocinonide, fluprednisolone, Aclovate, Alphatrex, Aristocort, Betatrex, Cortone, Diprolene, Valisone, Halog, Hytone, Kenalog, Lidex, Lotrisone, Synalar, Synemol, Topicort, Vytone, Westcort and Vioform. (27 Sep 1997) |
| corticosteroid side-chain-isomerase | <enzyme> Converts 11-deoxycorticosterone to 20-hydroxy-3-oxypregn-4-en-21-al; also acts as an epimerase at c-20 Registry number: EC 5.3.1.21 Synonym: corticosteroid side chain isomerase, ccsci (26 Jun 1999) |
| corticosteroid-binding globulin | <chemical> Chemical name: Transcortins (12 Dec 1998) |
| corticosteroid-binding protein | <chemical> Chemical name: Transcortins (12 Dec 1998) |
| corticosteroid-induced acne | The exacerbation of acne after corticosteroid use is a common drug reaction seen in adolescents. Lessening the dose of the corticosteroid will often diminish this effect. (27 Sep 1997) |
| corticosteroid-induced glaucoma | <ophthalmology> Glaucoma caused by a hereditary predisposition in which local instillation of eyedrops containing corticosteroid causes increased intraocular pressure. (05 Mar 2000) |
| corticosteroid-induced striae | <dermatology> High-dose glucocorticoid therapy causes atrophy of the skin and a failure of the normal regenerative process. Purple striae often develop over the individual's trunk or thighs. The colour fades when the drug is stopped, but the dermal atrophy remains. (27 Sep 1997) |
| corticosteroids | A group of synthetic hormones including prednisone, prednisolone, methylprednisolone and dexamethasone used in the treatment of some leukaemias and also to suppress graft rejection and graft-versus-host disease following bone marrow transplant. Side effects include an increased risk of infection. (13 Nov 1997) |
| corticosterone | <chemical> An adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid. Pharmacological action: steroidal anti-inflammatory agents. Chemical name: Pregn-4-ene-3,20-dione, 11,21-dihydroxy-, (11beta)- (12 Dec 1998) |
| corticosterone 15alpha-hydroxylase | <enzyme> Use of cytochrome p-450coh in which phe209 is replaced by asn gives the cytochrome p-450coh a high corticosterone 15alpha hydroxylase activity instead of a coumarin hydroxylase activity Registry number: EC 1.14.99.- Synonym: co 15-hydroxylase (26 Jun 1999) |
| corticothalamic | Pertaining to cortex and thalamus; the term is applied to fibres projecting from the cerebral cortex to the thalamus. (05 Mar 2000) |
| corticothalamic fibres | A general term designating nerve fibres originating from any area of the cerebral cortex and terminating in the nuclei of the thalamus. (05 Mar 2000) |
| corticotroph | A cell of the adenohypophysis that produces adrenocorticotropic hormone (ACTH). (05 Mar 2000) |
| corticotrophic adenoma | <oncology, tumour> ACTH-secreting tumour, posterior lobe of the pituitary (central location), usually less than 5mm. See: Cushing disease, pituitary adenoma. (12 Dec 1998) |
| cortex |
In the root, it is the layer of cells between the center and the edge.
Ãâó: library.thinkquest.org/3715/glossary_text.html
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| corticosteroid |
An adrenal-cortex steroid used to control inflammation. These include cortisone, fluticasone, beclomethasone, mometasone, and prednisone. Steroids are the body
Ãâó: www.ehealthmd.com/library/Emphysema/EMP_glossary.h...
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| cortisol |
A hormone produced by the adrenal cortex. High levels of cortisol have been associated with stress.
Ãâó: www.ehealthmd.com/library/depressionpregnancy/DPR_...
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| corticosteroid |
Hormones produced by the adrenal gland which are important to almost every function of cells and organs. They are divided into two groups: glucocorticoids and mineralocorticoids. Glucocorticoids regulate protein, carbohydrate, and fat metabolism. Mineralocorticoids regulate electrolyte balances.
Ãâó: www.peteducation.com/dict_alpha_listing.cfm
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| cortisol |
The main glucocorticoid; a hormone naturally produced by the adrenal gland; it is synthesized commercially as hydrocortisone and is used to reduce inflammation.
Ãâó: www.peteducation.com/dict_alpha_listing.cfm
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